Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 2 de 2
Filter
Add more filters










Database
Language
Publication year range
1.
Khirurgiia (Mosk) ; (11): 56-62, 2023.
Article in Russian | MEDLINE | ID: mdl-38010018

ABSTRACT

OBJECTIVE: To prevent purulent-septic complications in patients with destructive pancreatitis. MATERIAL AND METHODS: A cohort study included 488 patients with pancreatic necrosis: group 1 (n=331) - active surgical strategy, group 2 (n=157) - follow-up and therapy. We used binary logistic regression to predict purulent-septic complications. RESULTS: Original model of independent variables significantly (p<0.001) revealed 5.3 times higher risk of infectious complications after laparotomy within the first week after hospitalization. Incidence of these events increased by 2.8 times in patients biliary pancreatitis compared to alcohol-alimentary pancreatitis. Complication rate was higher in older patients (by 2.1% for each year). Risk of purulent-septic complications decreased by 57.4% in women compared to men. There was no significant correlation between risk of infectious complications and endoscopic procedures. Specificity and sensitivity of the model was 74.2 and 72.6%, respectively. CONCLUSION: Original model significantly predicts the risk of purulent-septic complications within the first week after hospitalization. Refusal of early active surgical strategy in these patients will significantly reduce the likelihood of purulent-septic complications.


Subject(s)
Pancreatitis, Acute Necrotizing , Male , Humans , Female , Aged , Pancreatitis, Acute Necrotizing/diagnosis , Pancreatitis, Acute Necrotizing/surgery , Cohort Studies , Endoscopy/methods , Necrosis
2.
Anesteziol Reanimatol ; (6): 68-71, 2010.
Article in Russian | MEDLINE | ID: mdl-21404452

ABSTRACT

The method of long-term continuous low-volume infusion of hydroxyethyl starch (low-flow low volume correction HES) is administrated for correction of fluid balance disorders. The method is aimed to improve the outcomes in preeclamsia patients with multiple organ dysfunction and failure, as the most severe manifestation of system inflammatory response syndrome. After 4 days of the intensive care with application of the developed method in patients with preeclamsia the total body water level is decreased to the normal physiological level, the oedemas are significantly reduced or ceased, the haemodynamics stabilizes, which leads to the reduce of neurologic symptoms. The suggested method of low-flow low volume correction HES, in dose of 15 ml/kg/day is a significant addition to the existing methods of homeostasis and preeclampsia correction.


Subject(s)
Hydroxyethyl Starch Derivatives/administration & dosage , Plasma Substitutes/administration & dosage , Pre-Eclampsia/therapy , Water-Electrolyte Balance , Adolescent , Adult , Blood Proteins/metabolism , Capillary Leak Syndrome/prevention & control , Female , Hemodynamics/physiology , Humans , Hypertonic Solutions , Infusions, Intravenous , Long-Term Care , Osmolar Concentration , Pre-Eclampsia/metabolism , Pre-Eclampsia/physiopathology , Pregnancy , Treatment Outcome , Young Adult
SELECTION OF CITATIONS
SEARCH DETAIL
...