ABSTRACT
INTRODUCTION: Orthotopic neobladder (ONB) and ileal conduit (IC) are the most commonly practiced techniques of urinary diversion (UD) after radical cystectomy (RC) in bladder cancer patients. Data in the literature is still discordant regarding which UD technique offers the best HR-QoL. OBJECTIVE: The objective was to compare HR-QoL in patients undergoing ONB and IC after RC, through a systematic review of the literature and meta-analysis. MATERIAL AND METHODS: We performed a literature search of PubMed, ScienceDirect, CochraneLibrary and ClinicalTrials.Gov in September 2017 according to the Cochrane Handbook and the Preferred Reporting Items for Systematic Reviews and Meta-Analyzes. The studies were evaluated according to the "Oxford Center for Evidence-Based Medicine" criteria. The outcome measures evaluated were subdomains' scores of Bladder Cancer Index BCI: urinary function (UF), urinary bother (UB), bowel function (BF), bowel bother (BB), sexual function (SF) and sexual bother (SB). Continuous outcomes were compared using weighted means differences, with 95% confidence intervals. The presence of publication bias was examined by funnel plots. RESULTS: Four studies met the inclusion criteria. The pooled results demonstrated better UF and UB scores in IC patients: differences were -18.17 (95% CI: -27.49, -8.84, P=0.0001) and -3.72 (95% CI: -6.66, -0.79, P=0.01) respectively. There was no significant difference between IC and ONB patients in terms of BF and BB. SF was significantly better in ONB patients: the difference was 12.7 (95% CI, 6.32, 19.08, P<0.0001). However no significant difference was observed regarding SB. CONCLUSION: This meta-analysis of non-randomized studies demonstrated a better HR-QoL in urinary outcomes in IC patients compared with ONB patients.
Subject(s)
Cystectomy/methods , Quality of Life , Urinary Bladder Neoplasms/surgery , Urinary Diversion , Urinary Reservoirs, Continent , Humans , Randomized Controlled Trials as Topic , Treatment Outcome , Urinary Diversion/methodsABSTRACT
INTRODUCTION: Postoperative ileus occurs in different degrees, in the majority of patients undergoing radical cystectomy, which may increase the length of hospital stay. The use of chewing gum has demonstrated its effectiveness in reducing time-to-bowel function and the length of hospital stay in several surgical procedures. OBJECTIVE: To evaluate the benefit of post-operative chewing gum use in patients undergoing radical cystectomy through a systematic review of the literature and meta-analysis. MATERIAL AND METHODS: We performed a literature search of MedLine, Scopus, CochraneLibrary and ClinicalTrials.Gov in March 2017 according to the Cochrane Handbook and the Preferred Reporting Items for Systematic Reviews and Meta-Analyzes. The studies were evaluated according to the "Oxford Center for Evidence-Based Medicine" criteria. The outcome measures evaluated were time-to-flatus, time-to-defecation, length of the hospital stay, and the rates of general and gastrointestinal postoperative complications. Continuous and dichotomous variables were compared respectively using weighted means differences and odds ratios with 95 % confidence intervals. The presence of publication bias was examined by funnel plots. RESULTS: Three studies (including 274 patients in total) met the inclusion criteria. The pooled results demonstrated a 11.82hour reduction in time-to-flatus (95 % CI : -15.43, -8.22h, P <0.00001), and 19.57hours in time-to-defecation (95 % CI : -29.33, -9.81h, P <0.0001), and a decreasing trend of 2.85 days in the length of the hospital stay (95 % CI : -6.13, -0.43, P=0.09), by the use of chewing gum. There was no significant difference between the "chewing gum" and "control" groups in terms of general and gastrointestinal complications (Peto Odds ratio 1.04 [0.60, 1.79], 95 % CI, P=0.89 and Peto Odds ratio 0.65 [0.26, 1.61], 95 % CI, P=0.35 respectively). CONCLUSION: Chewing gum may be recommended postoperatively in patients undergoing radical cystectomy to improve time-to-bowel function.
Subject(s)
Chewing Gum , Cystectomy , Gastrointestinal Motility , Intestinal Pseudo-Obstruction/prevention & control , Length of Stay , Postoperative Care , Recovery of Function , Defecation , Humans , Postoperative Care/methods , Postoperative Complications/prevention & control , Time FactorsABSTRACT
Retroperitoneal leiomyoma is a rare benign tumor of the retroperitoneum. We report a clinical case of a 43-year-old patient, who suffered from back pain and weight loss. Imaging revealed a retroperitoneal mass, then the patient had a total excision of the tumor. Histological examination of the surgical specimen concluded to retroperitoneal leiomyoma. The evolution was good without recurrence after 12 months.
Subject(s)
Leiomyoma/pathology , Retroperitoneal Neoplasms/pathology , Adult , Female , Humans , Leiomyoma/surgery , Low Back Pain/etiology , Retroperitoneal Neoplasms/surgery , Weight LossABSTRACT
The history of pelvic prolapse back to the era of the pharaohs, about 1500 years before Christ. Hippocrates practiced succussion. Grenades, pieces of soaked linen were used as pessaries.Over the centuries, the eolution in understanding of this female pathology led to different treatment modalities, some of which we can currently seem strange.
Subject(s)
Uterine Prolapse/history , Female , History, 16th Century , History, 17th Century , History, 18th Century , History, 19th Century , History, 20th Century , History, Ancient , Humans , Pessaries/historyABSTRACT
La variete de corps etrangers introduits dans l'appareil genito- urinaire defie l'imagination et peut confronter l'urologue aux difficultes de leur extraction. Si leur presence releve souvent d'une pratique douteuse d'origine psychiatrique; il faut noter la possibilite d'une migration a partir des espaces perivesicaux lors d'une chirurgie de voisinage ainsi qu'une introduction accidentelle durant une intervention transvesicale. Les symptomes du bas appareil urinaire; non specifiques; sont les circonstances fortuites de decouverte de corps etrangers intravesicaux. Bien que le pronostic vital ne soit pas engage; l'extraction chirurgicale ou endoscopique s'avere necessaire du fait de l'inflammation severe associee aux dommages vesicaux secondaires a ce corps etranger.Nous rapportons le cas d'un jeune patient admis aux urgences chez qui on trouve une broche d'osteosynthese compliquee d'une lithiase situee dans la vessie
Subject(s)
Administration, Intravesical , Foreign Bodies , Fracture FixationABSTRACT
OBJECTIVE: To discuss the diagnostic and the prognostic problems of vesicouterine fistulas (VUF) emphasizing on the therapeutic characteristics that lead to successful treatment. MATERIALS AND METHODS: The authors retrieve retrospective series of 16 cases, collected between 1989 and June 2006, and they analyze the clinical, diagnostic and therapeutic aspects. RESULTS: The patients were young (29-40 years) with an average having three children. Cesarean was the most frequent etiology. The presentation symptoms were hematuria (in five cases), a urinary incontinence through the vagina (in eight cases) and both of them (in three cases). The diagnosis was suspected from the history and confirmed by the additional analyses. The treatment was surgical (excision of the fistulas) in 15 cases with an average follow-up of 2.5 years, the results on the functional aspect were satisfactory hence they were marked by the absence of urinary incontinence as well as the hematuria. On the obstetric aspect, the occurrence of pregnancy was noted in a patient at four years post-VUF repair. CONCLUSION: Vesicouterine fistulas are not very frequent and most often secondary to a cesarean or to consequences of difficult delivery. The treatment is essentially preventive by improving the obstetrical techniques through avoiding the bladder injuries during the cesareans.
Subject(s)
Fistula/surgery , Urinary Bladder Fistula/surgery , Uterine Diseases/surgery , Adult , Cesarean Section/adverse effects , Female , Fistula/diagnosis , Fistula/etiology , Hematuria/etiology , Humans , Middle Aged , Obstetric Labor Complications , Pregnancy , Retrospective Studies , Urinary Bladder Fistula/diagnosis , Urinary Bladder Fistula/etiology , Urinary Incontinence/etiology , Uterine Diseases/diagnosis , Uterine Diseases/etiologyABSTRACT
Objectif : Rapporter les particularites epidemiologiques; anatomo-cliniques; pronostiques et therapeutiques de l'atteinte genitale masculine de la tuberculose avec revue de la litterature. Patients et methodes : Il s'agit d'une etude retrospective portant sur 22 cas de lesions genitales de tuberculose confirmees. Le diagnostic a ete pose sur un faisceau d'arguments cliniques; bacteriologiques; radiologiques et histologiques. Un traitement anti-tuberculeuse a ete instauree systematiquement. La surveillance a ete clinique; biologique et radiologique. Resultats: Les motifs de consultation ont ete par ordre de frequence decroissant : l'epididymite chronique (11 cas); une fistule scrotale (6 cas); une hydrocele (6 cas); une retention d'urine (3 cas) et une sterilite (1 cas). L'examen clinique a retrouve un nodule epididymaire dans 11 cas et une hydrocele dans 10 cas. Une leucocyturie sans germe a ete retrouvee dans un cas. L'echographie scrotale realisee a mis en evidence des lesions epididymaires dans 8 cas. Le diagnostic de certitude a ete pose sur l'examen anatomopathologique des pieces operatoires (13 cas); de fragments biopsiques (8 cas); et par la decouverte du bacille de Koch dans les urines (1 cas). L'urographie intraveineuse realisee systematiquement a retrouve des lesions urinaires associees dans 5 cas. L'evolution a ete favorable dans tous les cas.Conclusion: L'atteinte tuberculeuse isolee des organes genitaux masculins est de diagnostic difficile en dehors d'un contexte endemique tuberculeux. Une etiologie tuberculeuse doit etre suspectee devant toute orchiepidydimite trainante; particulierement sur terrain debilite ou devant une notion d'hypofertilite. Le traitement medical reste efficace en cas de diagnostic precoce; alors que la chirurgie est reservee aux cas resistants ou compliques
Subject(s)
Antitubercular Agents , Prostatitis , Tuberculosis, Urogenital , Tuberculosis, Urogenital/epidemiology , Tuberculosis, Urogenital/pathologyABSTRACT
Objective: We report six cases of primitive cancer of the urethra out of a total of 1109 cases of urologic cancers hospitalized during a period of 12 years. Patients and Methods: From 1990 to 2001 six patients (four males; two females) were hospitalized for cancer of the urethra. The tumors were analyzed according to the classification of Grabstald. All the patients were explored by retrograde urethrocystography showing an irregular image of the urethra and at times opacifying the sinus ways. Urethrocystoscopy showed the site of the tumor and its aspect and allowed for diagnostic biopsies. In five cases it revealed an epidermoid cancer and an adenocarcinoma in one case. The treatment used depended on the stage of the disease and the general condition of the patients. Two patients underwent radical pelvectomy without any adjuvant treatment. Two patients with disseminated disease received palliative treatment by radiotherapy. The two remaining patients having refused surgical treatment were also treated by radiotherapy alone. Results: Overall; the average rate of survival was 17.5 months (3 to 60 months). The best results were achieved with surgical treatment. Two of the patients referred to the oncologist for palliative radiotherapy died within 3 and 6 months; respectively. One patient treated by radiotherapy alone after having refused surgical treatment presented 6 months later with a long post-radiation stenosis of the urethra. Since the patient still refused surgical treatment; he was treated by final cystostomy. The last patient also treated by exclusive radiotherapy is being followed up by the radiologists. Conclusion: Primitive cancer of the urethra is rare. Its semiology is not very specific which explains the frequently delayed diagnosis. It is the meticulous examination of the urethra which allows the diagnosis. The treatment of choice is surgery and/or radiotherapy
Subject(s)
Case Reports , Ureteral Neoplasms/radiotherapy , Ureteral Neoplasms/surgeryABSTRACT
Rare congenital malformation, bladder exstrophy is usually treated soon after birth. Based on three cases report of bladder exstrophy in adulthood (two men and one women aged from 21 to 25 years), the authors emphasize the importance of psychological, sexual, and social disorders caused by this affection treated at this age. Urinary problems were excluded of this study. The authors stress the necessity of an early management of this malformation, if possible at birth in order to minimize these consequences.
Subject(s)
Bladder Exstrophy/complications , Bladder Exstrophy/psychology , Sexual Dysfunction, Physiological/etiology , Adult , Age Factors , Bladder Exstrophy/surgery , Female , Humans , Interpersonal Relations , Male , Social Behavior , Stress, PsychologicalABSTRACT
We report one case of retroperitoneal liposarcoma treated by surgery and radiotherapy. With the literature, we discuss the pathologic and therapeutic aspect of this lesion.
Subject(s)
Liposarcoma/pathology , Liposarcoma/surgery , Retroperitoneal Neoplasms/pathology , Retroperitoneal Neoplasms/surgery , Diagnosis, Differential , Female , Humans , Liposarcoma/radiotherapy , Middle Aged , Prognosis , Radiotherapy, Adjuvant , Retroperitoneal Neoplasms/radiotherapy , Tomography, X-Ray Computed , Treatment OutcomeABSTRACT
OBJECTIVE: To approach the treatment of Fournier's gangrene. So, pathophysiology and etiology are recalled. METHODS: The authors present 51 cases of Fournier's gangrene treated from 1989 to 1998, their age ranged from 19 to 89 years. Data were collected on admission signs and symptoms, physical examination. Aggressive surgical debridement of all necrotic tissues was performed, Intravenous antibiotics and resuscitation fluid were also administered. RESULTS: All patients were male. In 20 cases (39%), there was no identifiable cause, and in 31 cases (61%), the etiology of gangrene was urethral (33%), anorectal (28%) and unknown (19%). The average hospital stay was 30 days. Three cases underwent unilateral orchidectomy, six colostomy and in 17 cases, a suprapubic catheter was inserted. Mortality was high (18%) and essentially associated to debilated state and toxi-infectious context. CONCLUSION: Fournier's gangrene is a true urologic emergency potential lethal, which requires aggressive antibiotic and surgical treatment.
Subject(s)
Fournier Gangrene/diagnosis , Fournier Gangrene/therapy , Adult , Aged , Aged, 80 and over , Humans , Male , Middle Aged , Perineum , ScrotumABSTRACT
We report an uncommon case of unilateral spontaneous hematoma of the right adrenal gland in a 22-year old young man. Preoperative diagnosis was made by ultrasonography and CT-scan. A right adrenalectomy was performed. Pathological evaluation showed an isolated hematoma without adrenal abnormalities. The diagnostic and therapeutic aspects are discussed.
Subject(s)
Adrenal Gland Diseases/diagnosis , Hematoma/diagnosis , Adult , Female , HumansABSTRACT
The authors report a case of transitional cell carcinoma of the left ureteral stump in a 66-year old man treated by nephrectomy for pyonephrosis 6 years previously and cystoprostatectomy for bladder tumour 13 years previously. In the light of this case and based on a review of the literature, they essentially discuss the diagnostic and aetiopathogenic problems raised by this disease.
Subject(s)
Carcinoma, Transitional Cell/diagnosis , Nephrectomy , Postoperative Complications/diagnosis , Pyelonephritis/surgery , Ureter/surgery , Ureteral Neoplasms/diagnosis , Aged , Humans , MaleABSTRACT
Bladder exstrophy is a malformation which the incidence is estimated at 3.3 per 100,000 births. It is usually treated in the first hours of life. The authors report three cases of bladder exstrophy treated in adult life with continent urinary diversion such as Benchekroun continent ileocaecal bladder (CICB). After a literature review on the management of bladder exstrophy, they studied clinical and therapeutical particularities of the bladder exstrophy in adulthood.
Subject(s)
Bladder Exstrophy/surgery , Adult , Female , Humans , Male , Urinary Diversion/methods , Urinary Reservoirs, ContinentABSTRACT
OBJECTIVE: To review the clinical, imaging and therapeutic aspects of urogenital tuberculosis. MATERIAL AND METHODS: From April 1989 to April 1999, 57 patients with urogenital tuberculosis were reviewed in our department. This series consisted of 32 males and 25 females with a mean age of 40 years (range: 18 to 72 years). RESULTS: The most frequent clinical symptoms were irritative symptoms (47.3%). Fever, anorexia and weight loss were rare (11%). 16% of patients had an isolated genital lesion. 14% presented with renal failure (mean serum creatinine: 18 mg/l). Only 3 cases (5.2%) presented with bacilluria. Urography showed abnormalities in 80% of cases. The most frequent abnormality was a non-functioning silent kidney in 23 cases (40.3%). The positive diagnosis was based on bacteriological (5 cases) and histological data (52 cases). Treatment consisted of antituberculous chemotherapy in all patients, in combination with surgery (75%), and/or endourological procedures (26.3%). Nephrectomy is still indicated for non-functioning tuberculous kidneys in order to prevent the development of hypertension, abscess and fistulas. CONCLUSION: The diagnosis of urogenital tuberculosis is difficult and often late. A surgical or endourological procedure is often necessary to preserve renal function and to improve quality of life.
Subject(s)
Tuberculosis, Urogenital , Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Retrospective Studies , Tuberculosis, Urogenital/diagnosis , Tuberculosis, Urogenital/therapyABSTRACT
We report an unusual case of a mixed granulosa-Sertoli-Leydig cell testicular tumor in a 16 year old man, who presented with bilateral gynaecomastia. A few cases have been published in the literature. Based on a case report, the authors describe the clinical, histopathological and therapeutical features of this rare affection.
Subject(s)
Granulosa Cell Tumor/pathology , Leydig Cell Tumor/pathology , Neoplasms, Multiple Primary/pathology , Sertoli Cell Tumor/pathology , Testicular Neoplasms/pathology , Adolescent , Humans , MaleABSTRACT
OBJECTIVE: To evaluate the aetiopathogenic, diagnostic and therapeutic aspects of urethral diverticula in women. MATERIAL AND METHODS: Over a 10-year period (January 1990 to December 1999), 15 patients with a mean age of 36 years (range: 25 to 46 years) with urethral diverticulum were included in this study. The mean parity was 2 with a history of long and difficult delivery in 6 cases. All patients presented lower urinary tract symptoms with a clinical diverticulum on gynaecological examination (14 cases) or on retrograde and voiding cystourethrography (14 cases) or intravenous urography (one case). Diverticulectomy was performed via a transvaginal approach in the dorsal position. RESULTS: There were no postoperative complications. All patients were reviewed with a mean follow-up of 3 years. The urinary symptoms had completely disappeared in 14 cases. One patient was reoperated for recurrent diverticulum. CONCLUSION: Young women with recurrent voiding disorders must be examined for the presence of urethral diverticulum that can be confirmed by cystourethrography. Transvaginal diverticulectomy in the lithotomy position is the operation which ensures the best results.
Subject(s)
Diverticulum , Urethral Diseases , Adult , Diverticulum/diagnosis , Diverticulum/etiology , Diverticulum/surgery , Female , Humans , Middle Aged , Urethral Diseases/diagnosis , Urethral Diseases/etiology , Urethral Diseases/surgeryABSTRACT
Two patients presenting complex tuberculous ureteral strictures on an only existing kidney were treated with definitive double J stent changed every 6 months. This treatment modality was well tolerated. On the basis of two cases and literature review, different therapeutic measures are discussed.
Subject(s)
Tuberculosis, Urogenital/therapy , Ureteral Diseases/microbiology , Ureteral Diseases/therapy , Ureteral Obstruction/microbiology , Ureteral Obstruction/therapy , Urinary Catheterization/instrumentation , Adult , Equipment Design , Humans , MaleABSTRACT
Between January 1990 and December 1997, 61 patients with renal calculi underwent percutaneous nepholithotomy. In the immediate postoperative period, 49 renal units (80.3%) were stone-free. At three months, our overall success rate was 91.8% after spontaneous elimination of non-significant residual calculi (< 3 mm). Complications were observed in 9.8% (six cases); hemorrhage and sepsis were the major complications. Percutaneous nephrolithotomy is an effective, safe and reliable alternative to the open operation.
Subject(s)
Kidney Calculi/therapy , Lithotripsy , Nephrostomy, Percutaneous , Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Recurrence , Retrospective Studies , Treatment OutcomeABSTRACT
We report a case of urteroileal fistula in a young 22 year-old-man with Crohn's disease, who presented with microscopic hematuria and severe diarrhea. Excretory urogram and retrograde pyelography showed a fistula between the right ureter and the terminal ileum which was successfully managed with conservative approach using a double J ureteral stent.
