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Carbohydr Res ; 343(1): 155-8, 2008 Jan 14.
Article in English | MEDLINE | ID: mdl-18005952

ABSTRACT

In addition to apigenin, apigenin 7-O-glucoside, kaempferol 3-O-glucoside, kaempferol 3,7-di-O-rhamnoside, quercetin, and quercetin 3-O-glucoside, the methanolic extract of Fagonia taeckholmiana afforded a new compound identified as kaempferol 3-O-beta-l-arabinopyranosyl-(1-->4)-alpha-l-rhamnopyranoside-7-O-alpha-l-rhamnopyranoside. Identification of the isolated compounds was based on chemical and spectroscopic analyses including UV, FABMS, (1)H, (13)C and 2D NMR, and DEPT. The cytotoxic activities of the compounds against several cancer cell lines were determined.


Subject(s)
Antineoplastic Agents/isolation & purification , Glycosides/isolation & purification , Plants, Medicinal/chemistry , Antineoplastic Agents/pharmacology , Cell Line, Tumor , Cell Survival/drug effects , Glycosides/chemistry , Glycosides/pharmacology , Humans , Kaempferols , Methanol , Plant Extracts , Trisaccharides
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