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1.
Int J Gynecol Cancer ; 19(5): 867-72, 2009 Jul.
Article in English | MEDLINE | ID: mdl-19574775

ABSTRACT

The Risk of Malignancy Index (RMI) is used for the prediction of ovarian malignancy. It includes menopausal status, carbohydrate antigen 125 serum levels, and ultrasound criteria. Three-dimensional power Doppler (3-DPD) is a reproducible investigation for assessment of tumor vascularity, classifying vascularity to avascular, parallel, and chaotic patterns. In this study; 3-DPD was added to RMI for prediction of malignancy in 400 cases of ovarian masses. Sensitivity of RMI for prediction of malignancy was 88%, with a cutoff value of 202.5 at 95% confidence interval. Sensitivity of 3-DPD for prediction of malignancy was 75%, adding 3-DPD to RMI increased its sensitivity to 99%. Considering the pilot nature of the study, further studies are needed to corroborate such findings.


Subject(s)
CA-125 Antigen/blood , Neovascularization, Pathologic/blood , Neovascularization, Pathologic/diagnostic imaging , Ovarian Neoplasms/blood supply , Ultrasonography, Doppler , Adenocarcinoma, Clear Cell/blood supply , Adenocarcinoma, Mucinous/blood supply , Adolescent , Adult , Aged , Aged, 80 and over , Carcinoma, Papillary/blood supply , Child , Cystadenocarcinoma, Serous/blood supply , Diagnosis, Differential , Female , Humans , Imaging, Three-Dimensional , Menopause , Middle Aged , Prognosis , Sensitivity and Specificity , Young Adult
2.
Acta Anat (Basel) ; 91(3): 350-61, 1975.
Article in English | MEDLINE | ID: mdl-1155000

ABSTRACT

A comparative study of the intrinsic innervation in desert rodents (kangaroo rats) and others (albino rats) was carried out in an attempt to understand the functional anatomy of the bladder in these animals which are known to sustain severe water restraint. The bladder of the albino rat was innervated by predominantly thin nerves, more numerous beaded endings and few ganglia. That of the kangaroo rat had more numerous thick nerves (pre-ganglionic), large verve trunks, and ganglia which were extensively distributed in the wall. These findings indicate that the bladder of the albino rat depends mainly on the intrinsic innervation and facilatory micturition reflexes, while that of the kangaroo rat is intrinsically regulated, depending on a short neuron system. It was concluded that all the structural differences found might be essential for constant urine retention.


Subject(s)
Urinary Bladder/innervation , Animals , Axons/enzymology , Cholinesterases/metabolism , Dipodomys , Female , Ganglia/enzymology , Histocytochemistry , Male , Myofibrils/enzymology , Rats , Species Specificity , Urinary Bladder/anatomy & histology , Urinary Bladder/enzymology
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