The temperature dependence of the speed of sound in bovine bone marrow at 750 kHz.

We present values for the speed of sound (SOS) in bovine bone marrow as a function of temperature between 17 degrees C and 44 degrees C. The measurements were made using a time-of-flight approach on a volume of roughly 10 mL, at 750 kHz. The equipment was validated using both distilled water and castor oil. The results show a linear response with SOS changing from 1456.23 ms(-1) at 17 degrees C to 1342.40 ms(-1) at 44 degrees C. The mean value at 37 degrees C was (1371.91 ms(-1)). The temperature coefficient of the SOS was found to be -4.21 +/- 0.19 ms(-1) degrees C(-1). This was well fitted to a least squares model with R2 = 0.88.