Synthesis of some naphthylazosulphur compounds structurally related to certain antibilharzial drugs.

The synthesis of 5,5'-Bis[4-(N-mono and disubstituted aminoethylamino)-naphthylazo]-2.2'-dipyridyldisulphides has been achieved by the coupling of 2.2'-dipyridyldisulphide-5.5'-tetrazonium chloride with different N-mono and N.N-disubstituted N'-1-naphthylethylenediamines.

Synthesis and screening of some substituted 3.5-dioxopyrazolidines.

Seven new 3.5-dioxopyrazolidine derivatives, incorporating in their molecule a p-substituted benzoyl grouping, were synthesized. The preliminary screening of four selected compounds showed that 1-phenyl-2-[p-nitrobenzoyl]-4.4-diethyl-3.5-dioxopyrazolidine possesses a low order of antiinflammatory activity.