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1.
Oral Oncol ; 44(6): 608-12, 2008 Jun.
Article in English | MEDLINE | ID: mdl-17936674

ABSTRACT

Current management of N0 stage lip Squamous Cell Carcinoma (SCC) are prophylactic neck dissection, radiotherapy, or "watch and see" policy. The aim is the evaluation of the role of sentinel lymph node biopsy (SLNB) in their management based upon actual and not hypothetical presence of cervical lymph node (CLN) micrometastases as a same day procedure. Fourteen patients between November 2003 and August 2005 were included, nine men and five women, median age:57 years, (range 34-65 years). SLNB using preoperative lymphoscintigraphy and intra-operative localisation with patent blue and radioactive Tc(99m) Human Serum Albumin was performed. The median follow-up period was 26 months. Successful patent blue localisation in 13/14 whilst successful radio-localisation in all patients. Micrometastases were detected in 1/14 whom underwent therapeutic neck dissection. No local recurrence or regional lymph node involvement were detected. SLNB is a technically feasible and accurate approach for detection of CLN micrometastases in N0 stage lip SCC using the triple diagnostic localisation technique as a same day procedure.


Subject(s)
Ambulatory Surgical Procedures , Carcinoma, Squamous Cell/surgery , Lip Neoplasms/surgery , Sentinel Lymph Node Biopsy , Adult , Aged , Carcinoma, Squamous Cell/pathology , Coloring Agents , Female , Follow-Up Studies , Humans , Lip Neoplasms/pathology , Lymphatic Metastasis/diagnosis , Male , Middle Aged , Radiopharmaceuticals , Technetium Tc 99m Sulfur Colloid , Treatment Outcome
2.
Int J Gynecol Cancer ; 17(2): 536-42, 2007.
Article in English | MEDLINE | ID: mdl-17362327

ABSTRACT

Resection of anterior vaginal wall that occurs with some cases of anterior pelvic exenteration leaves the patient with a small and narrow vagina. This affects their sexual life leading to major psychologic problems, especially in young women. The aim of this study is to evaluate a new technique of vaginal reconstruction following anterior pelvic exenteration with clinical and cytohistologic follow-up. Between March 2002 and November 2004, ten sexually active female patients underwent vaginal reconstruction after radical cystectomy that required en bloc removal of the anterior vaginal wall, with a pedicle graft of greater omentum combined with a vicryl mesh. The mean age of the patients was 38 years. The mean operative time of the reconstructive procedure was 50 min. There were no complications regarding the reconstructive procedure. On follow-up, the neovagina accepted two fingers easily and showed a pink-colored smooth lining. Seven patients reported successful attempts of sexual intercourse. It was concluded that reconstruction of vagina after anterior pelvic exenteration in sexually active women can be done safely with the use of vicryl mesh combined with a pedicled omental graft. It is a simple, reliable, and not time-consuming technique. The long-term follow-up was very beneficial in detection of complete healing, postoperative infections, and hormonal activity of the graft and recurrence of malignancy.


Subject(s)
Omentum/transplantation , Pelvic Exenteration/rehabilitation , Plastic Surgery Procedures/methods , Polyglactin 910 , Surgical Mesh , Vagina/surgery , Adult , Female , Follow-Up Studies , Humans , Omentum/surgery , Pelvic Exenteration/adverse effects , Plastic Surgery Procedures/adverse effects , Sexual Behavior , Surgical Flaps , Vaginal Diseases/etiology , Vaginal Diseases/pathology
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