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1.
Ocul Immunol Inflamm ; 28(3): 524-531, 2020 Apr 02.
Article in English | MEDLINE | ID: mdl-31642742

ABSTRACT

Purpose: To describe the clinical experience with intermediate uveitis at six Egyptian tertiary eye centers.Methods: A multicenter retrospective chart review of all patients with intermediate uveitis seen at six ocular inflammation referral clinics in Egypt between January 2010 and January 2017.Results: The study included a total of 781 patients with intermediate uveitis. The study cohort comprised of 282 male and 499 female patients. In over half of our cohort (58.77%), no specific cause could be confirmed. The remaining patients had sarcoidosis (16.26%), tuberculosis (14.85%), multiple sclerosis (9.09%), and TINU (1.02%). By the end of our study, 62% of the affected eyes had a BCVA better than 20/40Conclusion: More than 40% of our patients with intermediate uveitis had sarcoidosis, tuberculosis, multiple sclerosis, or TINU as the underlying etiology. Owing to their potential morbidity, these diseases need to be considered in Egyptian patients presenting with intermediate uveitis.


Subject(s)
Tertiary Care Centers/statistics & numerical data , Uveitis, Intermediate/epidemiology , Visual Acuity , Adolescent , Adult , Age Distribution , Child , Egypt/epidemiology , Female , Humans , Incidence , Male , Middle Aged , Prognosis , Retrospective Studies , Sex Distribution , Young Adult
2.
Ocul Immunol Inflamm ; 27(6): 897-904, 2019.
Article in English | MEDLINE | ID: mdl-31020877

ABSTRACT

Purpose: To describe the clinical experience with retinal vasculitis at 4 Egyptian tertiary eye centers. Methods: A multicenter retrospective chart review of all patients with retinal vasculitis encountered at 4 ocular inflammation referral clinics in Egypt between February 2013 and February 2018. Results: The study included 618 patients (327 males and 291 females). Of these, 284 patients had isolated retinal vasculitis, whereas 233 patients had an associated systemic inflammatory disease, the most frequent being Behçet's disease, followed by sarcoidosis. In 101 patients, retinal vasculitis could be attributed to an infectious etiology, and among this category, the most common was tuberculosis, followed by toxoplasmosis. Conclusion: In our Egyptian cohort, more than half the patients had their retinal vasculitis as part of a serious systemic disease, or as part of an infectious process, as tuberculosis. And in view of the significant potential morbidity of these conditions, the local ophthalmologists need to be aware of these entities when faced with patients presenting with retinal vasculitis.


Subject(s)
Hospitals, Special/statistics & numerical data , Ophthalmology/statistics & numerical data , Retinal Vasculitis/epidemiology , Tertiary Healthcare/statistics & numerical data , Adolescent , Adult , Aged , Behcet Syndrome/epidemiology , Child , Child, Preschool , Cohort Studies , Egypt/epidemiology , Female , Humans , Male , Middle Aged , Retinal Vasculitis/diagnosis , Retrospective Studies , Sarcoidosis/epidemiology , Toxoplasmosis, Ocular/epidemiology , Tuberculosis, Ocular/epidemiology
3.
Ocul Immunol Inflamm ; 27(6): 890-896, 2019.
Article in English | MEDLINE | ID: mdl-30412434

ABSTRACT

Purpose: To report the clinical experience with scleritis at four Egyptian tertiary care eye centers. Methods: Multicenter retrospective chart review of all patients with scleritis visiting four ocular inflammation referral clinics in Egypt between January 2013 and October 2017. Results: A total of 303 scleritis patients were enrolled. These included 76 male and 227 female patients. The most frequent subtype of scleritis was nodular anterior scleritis (44.9%). Rheumatoid arthritis and Wegener granulomatosis were the 2 most common systemic associations among our cohort. Eyes with necrotizing scleritis with inflammation had the lowest mean initial and final BCVA. Conclusion: The visual prognosis of an eye with scleritis varies with the subtype of scleral inflammation. In our cohort, it was found to be poorer in eyes with necrotizing scleritis with inflammation compared to other subtypes.


Subject(s)
Scleritis/epidemiology , Adolescent , Adult , Aged , Aged, 80 and over , Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Arthritis, Rheumatoid/epidemiology , Child , Cohort Studies , Egypt/epidemiology , Female , Glucocorticoids/therapeutic use , Granulomatosis with Polyangiitis/epidemiology , Humans , Immunosuppressive Agents/therapeutic use , Male , Middle Aged , Retrospective Studies , Scleritis/diagnosis , Scleritis/drug therapy , Visual Acuity/physiology
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