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1.
J Foot Ankle Surg ; 55(3): 509-12, 2016.
Article in English | MEDLINE | ID: mdl-26968232

ABSTRACT

Precontoured, low-profile plates with fixed dorsiflexion angles are becoming increasingly popular for first metatarsophalangeal joint fusion. We have concerns that the routine use of a precontoured plate can lead to excessive clinical dorsiflexion. The aim of our study was to investigate the relationship between the first metatarsophalangeal joint dorsiflexion intramedullary angle and the angle formed at the dorsal cortices where the plate is applied. We hypothesized that the dorsal cortical angle was significantly less dorsiflexed than the intramedullary angle. We measured both angles on lateral weightbearing radiographs of 40 consecutive individuals presenting with forefoot symptoms. The results demonstrated that the mean dorsal cortical angle was significantly smaller (mean 0.2° plantarflexion) compared with the intramedullary angle (mean 10.6° dorsiflexion; p < .001). The interobserver and intraobserver reliability of both the intramedullary and the dorsal cortical measurements was very good. In conclusion, the dorsal cortical angle is, on average, 10.8° smaller than the intramedullary angle, with a mean angle of almost 0°. This finding should be considered when selecting plates for first metatarsophalangeal joint fusion.


Subject(s)
Arthrodesis/instrumentation , Bone Plates , Metatarsophalangeal Joint/surgery , Prosthesis Design , Adult , Aged , Arthrodesis/methods , Female , Humans , Male , Metatarsophalangeal Joint/anatomy & histology , Metatarsophalangeal Joint/diagnostic imaging , Middle Aged , Radiography
2.
J Foot Ankle Surg ; 55(3): 612-8, 2016.
Article in English | MEDLINE | ID: mdl-26875767

ABSTRACT

Arthrodesis of the ankle and hindfoot in the setting of major deformity is challenging and associated with substantial risks. Patients often have significant comorbidities that lead to unforgiving soft tissues, poor vascularity, and poor bone quality. This creates the high-risk scenario of poor wound healing and poor implant fixation. Complications can be devastating, leading to loss of the limb and sepsis. The use of locking plate technology might provide biomechanical and operative technique advantages in such patients. We retrospectively assessed the results of the modified use of the PHILOS(™) (Synthes(®), Zuchwil, Switzerland) proximal humeral locking plate in 21 patients (11 males, 10 females; mean age 56.1 years, range 25 to 74 years) who had undergone complex fusions, including tibiotalar (n = 4), tibiocalcaneal (n = 7), or tibiotalocalcaneal (n =10) fusions. The average follow-up period was 14.6 (median 10, range 6 to 49) months. Of the 21 fusions, 18 achieved union (85.7%) at an average period of 4.8 (median 4.3, range 3 to 12) months. The overall deep infection rate was 14.3%. Overall, 17 of the 21 patients (81%) were satisfied with the result (good to excellent), 1 reported the result was fair (4.8%), and 3 patients developed nonunion and were dissatisfied with the procedure (14.3%). The present study is the largest series to date of patients undergoing complex ankle and hindfoot arthrodesis with the use of a proximal humeral locking plate and confirms previous findings that the technique is reliable with union, satisfaction, and complication rates comparable to those of other techniques.


Subject(s)
Ankle Joint/surgery , Arthrodesis/instrumentation , Bone Plates/statistics & numerical data , Foot Deformities, Acquired/surgery , Adult , Aged , Ankle Joint/diagnostic imaging , Ankle Joint/physiopathology , Arthrodesis/methods , Cohort Studies , Equipment Design , Female , Follow-Up Studies , Foot Deformities, Acquired/diagnostic imaging , Humans , Humerus , Male , Middle Aged , Patient Satisfaction/statistics & numerical data , Retrospective Studies , Risk Assessment , Time Factors , Treatment Outcome
3.
Sci Rep ; 5: 9323, 2015 Mar 20.
Article in English | MEDLINE | ID: mdl-25792356

ABSTRACT

UNLABELLED: The relationship between bone and skeletal muscle mass may be affected by physical training. No studies have prospectively examined the bone and skeletal muscle responses to a short controlled exercise-training programme. We hypothesised that a short exercise-training period would affect muscle and bone mass together. METHODS: Femoral bone and Rectus femoris Volumes (RFVOL) were determined by magnetic resonance imaging in 215 healthy army recruits, and bone mineral density (BMD) by Dual X-Ray Absorptiometry (DXA) and repeated after 12 weeks of regulated physical training. RESULTS: Pre-training, RFVOL was smaller in smokers than non-smokers (100.9 ± 20.2 vs. 108.7 ± 24.5, p = 0.018; 96.2 ± 16.9 vs. 104.8 ± 21.3, p = 0.002 for dominant/non-dominant limbs), although increases in RFVOL with training (of 14.2 ± 14.5% and 13.2 ± 15.6%] respectively, p < 0.001) were independent of prior smoking status. Pre-training RFVOL was related to bone cortical volume (r(2) = 0.21 and 0.30, p < 0.001 for dominant and non-dominant legs), and specifically to periosteal (r(2) = 0.21 and 0.23, p < 0.001) volume. Pre-training dominant RFVOL was independently associated with Total Hip BMD (p < 0.001). Training-related increases in RFVOL and bone volumes were related. Whilst smokers demonstrated lower muscle mass than non-smokers, differences were abolished with training. Training-related increases in muscle mass were related to increases in periosteal bone volume in both dominant and non-dominant legs.


Subject(s)
Exercise , Femur/physiology , Military Personnel , Muscle, Skeletal/physiology , Smoking , Absorptiometry, Photon , Adolescent , Adult , Femur/anatomy & histology , Humans , Muscle, Skeletal/anatomy & histology , Young Adult
4.
Eur J Pediatr ; 173(12): 1603-5, 2014 Dec.
Article in English | MEDLINE | ID: mdl-24061281

ABSTRACT

UNLABELLED: Peripheral nerve injuries may have a number of causes, most commonly mechanical. We describe a case of a deep peroneal nerve palsy in an adolescent boy which coincided with a large growth spurt. Spontaneous recovery of full function was seen without intervention. CONCLUSION: In the absence of any other causative factors, we believe that this growth spurt resulted in temporary compression of the deep peroneal nerve at the level of the knee producing transient neurapraxia.


Subject(s)
Growth , Paralysis/etiology , Peroneal Neuropathies/diagnosis , Child , Humans , Male , Peroneal Neuropathies/etiology
5.
JRSM Short Rep ; 4(6): 34, 2013 Jun.
Article in English | MEDLINE | ID: mdl-23885288

ABSTRACT

OBJECTIVE: There have been concerns about the potential increases in operating time associated with the use of individually wrapped presterilized small orthopaedic implants compared with our traditional method of screw banks. We set out to quantify this theory. DESIGN: Prospective experimental study. SETTING: Theatre. PARTICIPANTS: Orthopaedic Surgical Trainees and Theatre Scrub team. MAIN OUTCOME MEASURE: The time taken to complete the operation. RESULTS: The use of prepacked and sterilized implants added 2 min 56 s to the use of a bank with a full complement of normal screws that required tapping and 3 min 58 s if self-tapping screws were used (P < 0.001). CONCLUSION: Using individually wrapped presterilized small orthopaedic implants increases operating time.

6.
Foot Ankle Clin ; 18(2): 219-36, 2013 Jun.
Article in English | MEDLINE | ID: mdl-23707175

ABSTRACT

Although Lisfranc injuries are uncommon, prompt and accurate diagnosis of such injuries in athletes is essential in preventing career-ending injury. Undisplaced injuries have an excellent result with nonoperative treatment. The presence of any displacement warrants open reduction and anatomic fixation; although current evidence mostly supports screw fixation, plate fixation may avoid joint intrusion. It is imperative to warn athletes with significantly displaced injuries that there is a risk of a poor outcome, although some recent evidence suggests that return to elite competitive sports is still likely after surgical intervention. Severe injuries may have better outcomes with limited arthrodesis.


Subject(s)
Athletic Injuries/diagnosis , Foot Injuries/diagnosis , Fracture Fixation, Internal/methods , Joint Dislocations/diagnosis , Sprains and Strains/diagnosis , Athletes , Athletic Injuries/surgery , Evidence-Based Medicine , Foot Injuries/surgery , Humans , Joint Dislocations/surgery , Sprains and Strains/surgery , Treatment Outcome
7.
Knee Surg Sports Traumatol Arthrosc ; 21(6): 1434-46, 2013 Jun.
Article in English | MEDLINE | ID: mdl-23563815

ABSTRACT

Lisfranc injuries are a spectrum of injuries to the tarsometatarsal joint complex of the midfoot. These range from subtle ligamentous sprains, often seen in athletes, to fracture dislocations seen in high-energy injuries. Accurate and early diagnosis is important to optimise treatment and minimise long-term disability, but unfortunately, this is a frequently missed injury. Undisplaced injuries have excellent outcomes with non-operative treatment. Displaced injuries have worse outcomes and require anatomical reduction and internal fixation for the best outcome. Although evidence to date supports the use of screw fixation, plate fixation may avoid further articular joint damage and may have benefits. Recent evidence supports the use of limited arthrodesis in more complex injuries.


Subject(s)
Foot Injuries/diagnosis , Foot Injuries/surgery , Foot Joints/injuries , Ligaments, Articular/injuries , Algorithms , Foot Injuries/physiopathology , Foot Joints/physiopathology , Foot Joints/surgery , Humans , Ligaments, Articular/physiopathology
9.
Bone ; 52(1): 17-26, 2013 Jan.
Article in English | MEDLINE | ID: mdl-22985892

ABSTRACT

BACKGROUND: The development of osteoporosis is influenced by peak bone mass attained in youth - the influence of lifestyle factors upon which is poorly described, especially amongst males. We sought to address this issue in a large scale study. METHODS: Hip bone mineral density (dual X-ray absorptiometry, DXA), bone microarchitecture (calcaneal quantitative ultrasound, QUS) and femoral geometry (magnetic resonance imaging, MRI) were characterised in 723 healthy male military recruits (mean ± S.E. age 19.92 ± 0.09 years [range 16-18 years], height 177.67 ± 0.24 cm, weight 73.17 ± 0.37 kg) on entry to UK Army training. Association was sought with prior physical activity, smoking status and alcohol intake. RESULTS: DXA measures were made in 651, MRI measures in 650, and QUS measures in 572 recruits. Increasing levels of weight-bearing physical activity enhanced periostial bone apposition, increases in both total hip and femoral neck bone mineral density (BMD; p ≤ 0.0001 in both cases), and cortical [p<0.0001] and periostial bone volumes [p=0.016]. Smoking habit was associated with preserved bone geometry, but worse BMD [p=0.0001] and QUS characteristics [p ≤ 0.0005]. Moderate alcohol consumption was associated with greater BMD [p ≤ 0.015]. CONCLUSIONS: Whilst exercise (and perhaps moderate alcohol intake) is beneficial to bone morphometry, smoking is detrimental to bone mineral density in young males notable for the likely short duration of smoking to influence skeletal properties. However, differences in socio-economic status, lifestyle and related environmental factors may to some extent confound our results.


Subject(s)
Alcohol Drinking , Bone and Bones/anatomy & histology , Motor Activity , Smoking , Absorptiometry, Photon , Adolescent , Bone Density , Cohort Studies , Humans , Magnetic Resonance Imaging , Male , Phenotype , White People
10.
J Appl Physiol (1985) ; 112(4): 615-26, 2012 Feb.
Article in English | MEDLINE | ID: mdl-22114178

ABSTRACT

The skeletal response to short-term exercise training remains poorly described. We thus studied the lower limb skeletal response of 723 Caucasian male army recruits to a 12-wk training regime. Femoral bone volume was assessed using magnetic resonance imaging, bone ultrastructure by quantitative ultrasound (QUS), and bone mineral density (BMD) using dual-energy X-ray absorptiometry (DXA) of the hip. Left hip BMD increased with training (mean ± SD: 0.85 ± 3.24, 2.93 ± 4.85, and 1.89 ± 2.85% for femoral neck, Ward's area, and total hip, respectively; all P < 0.001). Left calcaneal broadband ultrasound attenuation rose 3.57 ± 0.5% (P < 0.001), and left and right femoral cortical volume by 1.09 ± 4.05 and 0.71 ± 4.05%, respectively (P = 0.0001 and 0.003), largely through the rise in periosteal volume (0.78 ± 3.14 and 0.59 ± 2.58% for right and left, respectively, P < 0.001) with endosteal volumes unchanged. Before training, DXA and QUS measures were independent of limb dominance. However, the dominant femur had higher periosteal (25,991.49 vs. 2,5572 mm(3), P < 0.001), endosteal (6,063.33 vs. 5,983.12 mm(3), P = 0.001), and cortical volumes (19,928 vs. 19,589.56 mm(3), P = 0.001). Changes in DXA, QUS, and magnetic resonance imaging measures were independent of limb dominance. We show, for the first time, that short-term exercise training in young men is associated not only with a rise in human femoral BMD, but also in femoral bone volume, the latter largely through a periosteal response.


Subject(s)
Bone and Bones/physiology , Exercise/physiology , Absorptiometry, Photon , Adolescent , Aging/physiology , Bone Density , Bone and Bones/anatomy & histology , Bone and Bones/diagnostic imaging , Calcification, Physiologic , Functional Laterality , Humans , Magnetic Resonance Imaging , Male , Prospective Studies , Ultrasonography , Young Adult
11.
Int J Shoulder Surg ; 5(1): 17-20, 2011 Jan.
Article in English | MEDLINE | ID: mdl-21660193

ABSTRACT

Malunion of proximal humeral fractures can lead to a severely impaired shoulder function. Loss of motion is often the main issue in patients and can be secondary to osseous, soft-tissue as well as neurological damage to the shoulder. Malunion of the articular surface of the humeral head can lead to pain, chronic degenerative changes secondary to joint incongruity and mechanical block to the range of movement. A 46-year-old otherwise healthy male chef presented with malunion and collapse of his previous plate fixation for a four-part proximal humerus fracture. We describe the first documented case of the use of a focal resurfacing system for dealing with such an osseous mechanical block in the presence of an otherwise preserved articular surface in a high-demand patient. HemiCAP can be successfully used in proximal humeral fracture malunion where there is a localized cartilage defect, allowing restoration of joint congruity while preserving the bone stock.

12.
Int J Cardiol ; 120(1): 52-8, 2007 Aug 09.
Article in English | MEDLINE | ID: mdl-17079035

ABSTRACT

BACKGROUND: Left ventricular mass is a risk factor for cardiovascular morbidity and mortality. Although factors associated with elevated left ventricular mass have been sought and studied extensively in elderly and in diseased subjects, few studies have examined the young and healthy. The aim of this study was to examine the possible influence of lifestyle on left ventricular mass in a large group of young men. METHODS: Left ventricular mass was assessed using cardiovascular magnetic resonance in 541 healthy Caucasian male army recruits. Anthropometric, lifestyle and blood pressure data were collected. RESULTS: Mean unadjusted left ventricular mass and left ventricular mass indexed to body surface area were 163.8+/-24.9 g and 86.6+/-10.2 g m(-2) respectively. In univariate analysis, age, height, weight, alcohol consumption, systolic blood pressure, diastolic blood pressure and indices of physical activity were positively associated with unadjusted left ventricular mass (all P<0.02). By contrast, smoking was associated with lower mean left ventricular mass; never smoked 167.5+/-25.8 g vs ex-smokers 159.1+/-25.2 g vs current smokers 161.0+/-23.1 g (P=0.007). Multivariate analysis revealed weight, systolic blood pressure, smoking status and indices of physical activity to be independent predictors of left ventricular mass. CONCLUSIONS: Our data confirm an association of age, body weight, height, physical activity, diastolic and systolic blood pressure with left ventricular mass. In addition, unexpectedly, we have found smoking is associated with lower left ventricular mass in a large sample of young healthy men. Although the latter association may result from confounding effects, such an interesting observation deserves further investigation.


Subject(s)
Alcohol Drinking , Heart Ventricles/anatomy & histology , Life Style , Smoking , Adolescent , Adult , Blood Pressure , Body Mass Index , Body Size , Humans , Magnetic Resonance Imaging , Male , Organ Size , Reference Values , White People
13.
Am J Clin Nutr ; 83(4): 912-7, 2006 Apr.
Article in English | MEDLINE | ID: mdl-16600946

ABSTRACT

BACKGROUND: The etiology of muscle wasting in chronic obstructive pulmonary disease (COPD) is incompletely understood. We previously showed that the D rather than the I polymorphic variant of the angiotensin-converting enzyme (ACE) gene is associated with preserved quadriceps strength in COPD. If the ACE D allele influences skeletal muscle through increased ACE-related kinin degradation [and reduced activity at the bradykinin type 2 receptor (BK(2)R)], we might expect a similar association with the +9 BK(2)R genotype in this population as well. OBJECTIVE: The objective was to test the hypothesis that the BK(2)R gene polymorphism is a determinant of fat-free mass and quadriceps strength in patients with COPD. DESIGN: In a cross-sectional design we determined BK(2)R genotype, fat-free mass, and quadriceps strength in 110 COPD patients with a mean (+/-SD) predicted forced expiratory volume in 1 s of 34.3 +/- 16.4% and in 104 healthy age-matched control subjects. RESULTS: The mean (+/-SD) fat-free mass index (in kg/m(2)) was significantly lower in 37 patients homozygous for the +9 allele than in carriers of the -9 allele (15.7 +/- 1.8 compared with 16.7 +/- 2.3; P = 0.038); the same pattern was true for quadriceps maximal voluntary force (30.8 +/- 10.4 and 36.4 +/- 12.8 kg; P = 0.02), respectively. No significant effect of BK(2)R genotype on inspiratory muscle strength or on any variable in control subjects was observed. There was no interaction between the effect of the BK(2)R and ACE genotypes on quadriceps strength. CONCLUSIONS: The genotype associated with reduced BK(2)R expression is associated with reduced fat-free mass and quadriceps strength in COPD. However, alterations in the activity at the BK(2)R do not seem to account for the previously identified association of quadriceps strength with ACE genotype.


Subject(s)
Muscle, Skeletal/metabolism , Polymorphism, Genetic , Pulmonary Disease, Chronic Obstructive/genetics , Pulmonary Disease, Chronic Obstructive/physiopathology , Receptors, Bradykinin/genetics , Receptors, Bradykinin/metabolism , Alleles , Case-Control Studies , Cohort Studies , Cross-Sectional Studies , Female , Genotype , Homozygote , Humans , Male , Middle Aged , Muscle, Skeletal/physiopathology , Peptidyl-Dipeptidase A/genetics , Respiratory Function Tests , Respiratory Muscles/metabolism , Respiratory Muscles/physiopathology
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