1.
Bioorg Med Chem
; 8(6): 1213-23, 2000 Jun.
Article
in English
| MEDLINE
| ID: mdl-10896102
ABSTRACT
Corticotropin releasing hormone (CRH, sometimes known as CRF) is an endogenous 41 amino acid peptide that has been implicated in the onset of pregnancy, the 'fight or flight' response, in addition to a large number of physiological disorders. Recently, medicinal chemists have developed a number of potent and selective compounds that show promise in a vast array of therapeutic uses. Herein we review the current status of research.