ABSTRACT
BACKGROUND: Laparoscopic ventral hernia repair has steadily gained recognition as an alternative to the open approach. However, the procedure can be technically challenging. The authors present their simple scroll technique for laparoscopic ventral hernia repair. METHODS: A total of 174 patients underwent laparoscopic ventral hernia repair using the scroll technique. The technique entails fixation of the rolled mesh to the anterior abdominal wall before it is unfolded. Patient characteristics, operative time, and complications were analyzed and compared with pooled data from the available literature on laparoscopic ventral hernia repair. RESULTS: The mean operative time was comparable with that reported by others (mean, 102 vs. 100 min). The hospital stay was shorter (mean, 1.8 vs. 2.4 h). During a mean follow-up period of 28 months, the recurrence rate was lower than that reported by others (1.7% vs. 4.3%). There were no mortalities and no cases of inadvertent bowel injury. CONCLUSION: The authors' scroll technique for laparoscopic repair is simple, feasible, and reproducible, with a short learning curve and a low recurrence rate.
Subject(s)
Hernia, Ventral/surgery , Laparoscopy/methods , Female , Humans , Length of Stay/statistics & numerical data , Male , Middle Aged , Postoperative Complications , Recurrence , Retrospective Studies , Surgical Mesh , Time Factors , Treatment OutcomeABSTRACT
One new, 3-O-[[[-alpha-L-rhamnopyranosyl-(1-->2)]-[beta-D-glucopyranosyl-(1-->3)]-beta-D-glucopyranosyl-(1-->2)]-beta-D-glucuronopyranosyl]-3beta,22alpha,24-trihydroxyolean-12-ene and two known triterpenoid saponins, 3-O-[[alpha-L-rhamnopyranosyl-(1-->2)]-[beta-D-glucopyranosyl-(1-->2)]-beta-D-glucuronopyranosyl]-3beta,22beta,24-trihydroxyolean-12-ene (azukisaponin V) and 3,16-di-O-beta-D-glucopyranosyl-3beta,6alpha,16beta-trihydroxycycloart-24-ene have been isolated from Astragalus trigonus. The structures were determined primarily by NMR spectroscopy. The assignment of NMR signals was performed by means of 1H-1H COSY, NOESY, ROESY, TOCSY, HMQC and HMBC experiments.
Subject(s)
Fabaceae/chemistry , Plant Extracts/chemistry , Saponins/chemistry , Triterpenes/chemistry , Carbohydrate Sequence , Chromatography , Egypt , Magnetic Resonance Spectroscopy , Mass Spectrometry , Models, Molecular , Molecular Conformation , Molecular Sequence Data , Oligosaccharides/chemistry , Oligosaccharides/isolation & purification , Plant Extracts/isolation & purification , Saponins/isolation & purification , Silicon Dioxide , Triterpenes/isolation & purificationABSTRACT
Two new triterpenoid saponins, 3-O-{[beta-D-glucopyranosyl-(1-->2)]-[alpha-L-arabinopyranosyl-(1- ->3)]- alpha-L-arabinopyranosyl}-ursolic acid-28-O-[beta-D-glucopyranosyl] ester (indicasaponin A), 3-O-{[beta-D-glucopyranosyl-(1-->2)]-[alpha-L-arabinopyranosyl-(1- ->3)]- alpha-L-arabinopyranosyl}-oleanolic acid-28-O-[beta-D-glucopyranosyl] ester (indicasaponin B) and two known triterpenoid saponins, 3-O-[beta-D-glucopyranosyl-(1-->3)-alpha-L-arabinopyranosyl]-ur solic acid-28-O-[beta-D-glucopyranosyl] ester, 3-O-[beta-D-glucopyranosyl-(1-->3)-alpha-L-arabinopyranosyl]-olean olic acid-28-O-[beta-D-glucopyranosyl] ester have been isolated from Fagonia indica. The structures were determined primarily by NMR spectroscopy. The assignment of NMR signals was performed by means of 1H-1H COSY, NOESY, ROESY, TOCSY, HMQC and HMBC experiments.
Subject(s)
Saponins/chemistry , Triterpenes/chemistry , Carbohydrate Conformation , Carbohydrate Sequence , Chromatography, High Pressure Liquid , Magnetic Resonance Spectroscopy , Mass Spectrometry , Molecular Sequence Data , Saponins/isolation & purificationABSTRACT
Different extracts of both fresh and dry leaves of Aloe eru A. Berger, A. vera L. Webb & Berth and A. arborescens Mill. were screened for their antifungal activity against Aspergillus niger, Cladosporium herbarum and Fusarium moniliforme. The toxicity of the isolated pure components were evaluated on the tested fungi. A comparative chromatographic study was performed to differentiate between natural components existing in various fractions and extracts of Aloe species and specific spray reagents were used for the detection of anthraquinones in the isolated components.
Subject(s)
Aloe/chemistry , Antifungal Agents/pharmacology , Plants, Medicinal , Antifungal Agents/chemistry , Butanols , Chromatography, Thin Layer , Ethanol , Fungi/drug effects , Microbial Sensitivity Tests , Plant Extracts/chemistry , Plant Extracts/pharmacology , Solvents , Spectrophotometry, Ultraviolet , WaterABSTRACT
Two novel triterpenoid saponins, Snatzkein C, (3beta, 20-dihydroxylupan-28-oic acid 3-O-[beta-D-galactopyranosyl-(1-->2)-beta-D-glucopyranosyl-28- O-beta-D-glucopyranoside) and Snatzkein D, (3beta, 20-dihydroxylupan-28-oic acid 3-O-[beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranosyl]-28-O-beta-D-++ +glucopyranoside), have been isolated from Arenaria filicaulis. Their structure and conformational behaviour were elucidated by one- and two-dimensional 1H NMR and 13C NMR spectroscopy.
Subject(s)
Saponins/chemistry , Triterpenes/chemistry , Carbohydrate Conformation , Carbohydrate Sequence , Models, Molecular , Molecular Conformation , Molecular Sequence Data , Nuclear Magnetic Resonance, Biomolecular , Saponins/isolation & purification , Triterpenes/isolation & purificationABSTRACT
Two new triterpenoid saponins, 3-O-[beta-D-2-O-sulphonylglucopyranosyl]-quinovic acid-28-O-[beta-D-glucopyranosyl] ester (zygophyloside G), 3-O-[alpha-L-arabinopyranosyl-(1-->2)-beta-D-quinovopyranosyl++ +]-quinovic acid-28-28-O-[beta-D-glucopyranosyl] ester (zygophyloside H), and seven known saponins have been isolated. The structures were established primarily on the basis of NMR spectroscopy. The assignment of all NMR signals was performed by means of 1H-1H COSY-45, NOESY, TOCSY, 13C APT, HMQC and HMBC experiments. The determination of the glycosylation sites was possible by the HMBC experiments.
Subject(s)
Plant Roots/chemistry , Saponins/isolation & purification , Magnetic Resonance Spectroscopy , Molecular Structure , Saponins/chemistryABSTRACT
Four novel triterpenoid saponins have been isolated from Gypsophila capillaris. Three were monodesmosidic: 3 beta-hydroxyolean-12-en-23,28-dioic acid 28-O-[beta-D-glucopyranosyl-(1-->3)-beta-D-glucopyranosyl-(1-->2)] [beta-D-galactopyranosyl(1-->6)]beta-D-glucopyranoside, 3 beta-hydroxyolean-12-en-23-oxo-28-oic acid 28-O-[beta-D-glucopyranosyl-(1-->2)-beta-D-galactopyranosyl-(1-->3)] [beta-D-glucopyranosyl(1-->6)]beta-D-galactopyranoside, 3 beta-hydroxyolean-12-en-23,28-dioic acid 28-O-[beta-D-glucopyranosyl-(1-->2)-beta-D-galactopyranosyl-(1-->3)] [beta-D-glucopyranosyl(1-->6)]beta-D-galactopyranoside. The fourth was bisdesmosidic: 3 beta-hydroxyolean-12-en-23,28-dioic acid 23-O-beta-D-glucopyranosyl-28-O-[beta-D-glucopyranosyl-(1-->2)-beta-D- galactopyranosyl-(1-->3)][beta-D-glucopyranosyl-(1-->6)]beta-D- galactopyranoside. The structures of the compounds were elucidated by 1D and 2D NMR techniques and from other spectroscopic evidence.
Subject(s)
Plants, Medicinal/chemistry , Saponins/chemistry , Triterpenes/chemistry , Carbohydrate Conformation , Carbohydrate Sequence , Egypt , Magnetic Resonance Spectroscopy , Molecular Sequence Data , Molecular Structure , Oligosaccharides/chemistry , Oligosaccharides/isolation & purification , Saponins/isolation & purification , Spectrometry, Mass, Fast Atom Bombardment , Triterpenes/isolation & purificationABSTRACT
Five pentacyclic triterpenoids have been isolated from the minor constituents of local liquorice roots, one of them has not been isolated before from liquorice root. Their structural formulae and stereochemical configuration was determined by spectroscopic methods. 13C and 1H NMR data have been compiled.
Subject(s)
Glycyrrhiza/analysis , Plants, Medicinal , Triterpenes/isolation & purification , Magnetic Resonance Spectroscopy , Molecular Structure , Triterpenes/chemistryABSTRACT
Elemol and beta-eudesmol have been isolated from the unsaponifiable fraction of the fatty matter of CYMBOPOGON PROXIMUS. Their structure and configuration were determined by spectroscopic methods.
