ABSTRACT
PURPOSE: The aim of this study was to histologically evaluate the effect of using growth hormone (GH) around immediate dental implants in fresh extraction sockets. MATERIALS AND METHODS: Six mongrel dogs had had their lower right and left first premolars extracted. For the right side, the control side, implants were placed immediately. For the left sides, the study side, GH powder was placed in the socket and then immediate implant placement was done. Animals were killed at 2, 6, and 12 weeks after surgery, and histological sections were stained with hematoxylin and eosin, and trichrome stains, and observed under light microscopy for the newly formed bone. RESULTS: Bone formation was obvious in both groups. But in study group, bone density had denser and well-oriented collagen fibers. An increase in bone response was observed with high local administration of GH. In the first phases of bone repair, the osteons were more organized; they were more organized by the 12th week. CONCLUSION: The use of GH powder around dental implants placed immediately in fresh extraction sockets enhanced periimplant bone response.
