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Org Biomol Chem
; 4(13): 2642-9, 2006 Jul 07.
Article
in English
| MEDLINE
| ID: mdl-16791329
ABSTRACT
A divergent synthesis of both diastereoisomers of (+/-)-(3-aminocyclopentane)alkylphosphinic acid is described. Both diastereoisomers are obtained in 5 steps from the key (+/-)-(3-hydroxycyclopent-1-ene)alkylphosphinate esters which are prepared via a palladium catalysed C-P bond forming reaction.