ABSTRACT
Neonatal lupus erythematosus (NLE) is a rare syndrome of newborns and infants defined by the presence of maternal autoantibodies and the characteristic clinical features of the infant. The clinical findings most often reported are congenital heart block and cutaneous lesions; however, many children have cardiomyopathy, hepatobiliary disease, and/or hematologic diatheses. We present the case of a 1-day-old African American boy who presented with an annular, ulcerated facial eruption at birth and went on to develop subacute cutaneous LE (SCLE) and heart block.
Subject(s)
Heart Block/congenital , Lupus Erythematosus, Cutaneous/congenital , Antibodies, Antinuclear/analysis , Female , Humans , Infant, Newborn , Lupus Erythematosus, Cutaneous/immunology , Male , Pregnancy , Pregnancy Complications/immunologyABSTRACT
Herpes labialis, a common condition characterized by recurrent vesicular eruptions primarily on the lips and perioral skin, causes pain and discomfort for millions of adults each year. Over the past several years, the major focus of herpes research has been on the treatment of genital herpes. However, several studies have been conducted to evaluate the efficacy of therapies specifically for herpes labialis. Last year in Cutis, we reviewed oral and topical therapies for herpes labialis. In this final part of the series, we review experimental and natural treatments that are available for herpes labialis and its associated symptoms.
Subject(s)
Herpes Labialis/drug therapy , Butylated Hydroxytoluene/therapeutic use , Humans , Idoxuridine/therapeutic use , Iontophoresis , Lysine/therapeutic use , Plant Preparations/therapeutic use , Povidone-Iodine/administration & dosageABSTRACT
Given the prevalence of herpes labialis, effective therapy has the potential to affect the lives of many and presents a challenge for clinicians. Over the last several years, most of the focus of herpes research has been on the treatment of genital herpes. Recently, however, several studies have been published examining the efficacy of therapies specifically for herpes labialis. Several therapeutic agents, both prescription and over-the-counter, are available for controlling and managing the disease. In this series of articles, we review oral and topical therapeutic agents that are available in the treatment of herpes labialis and its associated symptoms. This article will review oral treatment options.
