ABSTRACT
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening conditions with high morbidity and mortality. Supportive care management of SJS/TEN is highly variable. A systematic review of the literature was performed by dermatologists, ophthalmologists, intensivists, and gynecologists with expertise in SJS/TEN to generate statements for supportive care guideline development. Members of the Society of Dermatology Hospitalists with expertise in SJS/TEN were invited to participate in a modified, online Delphi-consensus. Participants were administered 9-point Likert scale questionnaires regarding 135 statements. The RAND/UCLA Appropriateness Method was used to evaluate and select proposed statements for guideline inclusion; statements with median ratings of 6.5 to 9 and a disagreement index of ≤1 were included in the guideline. For the final round, the guidelines were appraised by all of the participants. Included are an evidence-based discussion and recommendations for hospital setting and care team, wound care, ocular care, oral care, urogenital care, pain management, infection surveillance, fluid and electrolyte management, nutrition and stress ulcer prophylaxis, airway management, and anticoagulation in adult patients with SJS/TEN.
Subject(s)
Stevens-Johnson Syndrome/therapy , Adult , HumansABSTRACT
Resumen El cáncer de piel es uno de los tumores con mayor incidencia en el ser humano, por lo que se le debe de dar la importancia que se merece en la enseñanza del médico general, ya que en la mayoría de los casos es prevenible y curable. Existen dos tipos de cáncer de piel: el no melanoma, que se compone por el carcinoma basocelular y el espinocelular, y el melanoma. El pronóstico de curación dependerá de la detección precoz y la correcta extirpación.
Abstract Skin cancer is one of the most prevalent tumors in human beings, and it should get the required relevance in the training of the general practitioner because in most of the cases it is preventable and curable. There are two types of skin cancer: the non-melanoma (Basal Cell Carcinoma and Squamous Cell Carcinoma) and Melanoma. The prognosis depends on the early detection and its proper removal.
