ABSTRACT
PURPOSE: To report a rare case of atypical fibroxanthoma (AFX) of the bulbar conjunctiva, and to compare it with previously published cases of conjunctival AFX. METHODS: A 37-year-old woman developed a growth on the bulbar conjunctiva of her left eye that increased in size and redness over 4 months and was associated with blurry vision in the left eye, occasional diplopia, irritation of the eye, and increasing tearing. The mass was surgically excised. RESULTS: Slit-lamp examination disclosed a highly vascularized conjunctival lesion with intact lustrous epithelium and a raised nodular edge encroaching on the nasal corneal limbus of the left eye. Pathological examination and immunohistochemistry were diagnostic of AFX. CONCLUSIONS: AFX of the conjunctiva is rare, with this being only the fifth example of this neoplasm reported at this site. Complete surgical excision is the most appropriate treatment option.
Subject(s)
Conjunctival Diseases/pathology , Xanthomatosis/pathology , Adult , Alkylating Agents/administration & dosage , Combined Modality Therapy , Conjunctival Diseases/therapy , Cryotherapy , Female , Humans , Limbus Corneae/pathology , Mitomycin/administration & dosage , Sclera/drug effects , Tenon Capsule/drug effects , Xanthomatosis/therapyABSTRACT
A 38-year-old man presented for evaluation of new-onset left testicular pain with swelling. Testicular ultrasound revealed multiple intraparenchymal hypoechoic areas in the inferior portion of the left testicle. The patient was treated with a radical inguinal orchiectomy. Pathologic evaluation revealed intratesticular vasculitis, with involvement of medium-sized arteries. This appears to be a rare case of isolated testicular vasculitis, in the absence of any systemic symptoms.
Subject(s)
Autoimmune Diseases/diagnosis , Orchitis/etiology , Testis/blood supply , Testis/pathology , Vasculitis/diagnosis , Adult , Antibodies, Antinuclear/blood , Autoantibodies/blood , Autoimmune Diseases/blood , Autoimmune Diseases/diagnostic imaging , Autoimmune Diseases/surgery , Blood Sedimentation , C-Reactive Protein/metabolism , Humans , Male , Orchiectomy/methods , Orchitis/blood , Orchitis/diagnostic imaging , Orchitis/surgery , Testis/diagnostic imaging , Testis/surgery , Ultrasonography , Vasculitis/blood , Vasculitis/diagnostic imagingABSTRACT
We present 3 adults with cardiac rhabdomyomas, 2 in the atria and 1 in the right ventricle. One atrial tumor was discovered incidentally, and 1 resulted in supraventricular tachycardia. The ventricular lesion caused ventricular tachycardia. Compared with congenital rhabdomyomas, the tumors are relatively cellular, the cells are smaller, there are few spider cells, and there is evidence of cell proliferation. Two of the 3 tumors demonstrated spindling in contrast to adult rhabdomyomas of the head and neck. Although surgical excision was possible in all patients, long-term follow-up will be required to determine the true biologic behavior of these neoplasms.
