ABSTRACT
Fixed drug eruptions often have a characteristic appearance, which, when correlated with the clinical history, can be easily identified. However, multifocal fixed drug eruptions, especially the non-pigmenting variety, can present a diagnostic challenge, especially in the absence of a complete medication history. We present such a case, in which the patient was taking two over-the-counter medications, both of which contain uncommon causes of multifocal fixed drug eruptions.
Subject(s)
Drug Eruptions/diagnosis , Erythema Multiforme/diagnosis , Acetaminophen/adverse effects , Adolescent , Diagnosis, Differential , Drug Eruptions/prevention & control , Erythema Multiforme/chemically induced , Female , Humans , Ibuprofen/adverse effects , Secondary PreventionABSTRACT
We present a case of cutaneous and systemic infection with Scedosporium apiospermum occurring in a patient with systemic lupus erythematosus. Scedosporium apiospermum is a rare cause of systemic mycosis but is associated with a high rate of mortality in immunocompromised hosts. Because the patient presented in an advanced state of infection, supportive measures were unsuccessful and definitive diagnosis could not be made until postmortem examination. We discuss the presentation, pathology, diagnosis, and treatment strategies for Scedosporium infection.
Subject(s)
Mycetoma/diagnosis , Mycetoma/microbiology , Scedosporium/isolation & purification , Aged , Autopsy , Biopsy , Diagnosis, Differential , Fatal Outcome , Female , Humans , Lupus Erythematosus, Systemic/complicationsABSTRACT
Cutaneous endometriosis is a rare condition, especially in patients without a history of abdominal or pelvic surgery or known preexisting endometriosis. Most cases present with cyclic pain and bleeding at the site of an umbilical cutaneous nodule correlating with menses. We present an atypical case of primary cutaneous endometriosis of the umbilicus without a prior history of abdominal or pelvic surgery and without cyclic pain or bleeding.