ABSTRACT
Uterine adenosarcoma is an apparently benign mixed tumor with a muller type epithelial component and a sarcomatous stromal component. We present a patient with remodeled genital prolapse who developed a bifocal localization in the endometrium and vagina. These tumors are uncommon, 8% of the sarcomatous tumors of the uterus. Their usual presentation may mimic cervical or endometrial polyps. Pathology is required for positive diagnosis which evidences the two components. The diagnosis may be missed at the first examination (two-thirds of the cases in certain series). Treatment is surgical with hysterectomy in peri- or post-menopaused women and tumoral excision or curettage in younger women. The prognosis is good but can worsen if invasion extends beyond one-third of the myometrial thickness or if pure sarcomatous transformation occurs.
Subject(s)
Adenosarcoma/pathology , Mixed Tumor, Mullerian/pathology , Uterine Neoplasms/pathology , Uterine Prolapse , Vaginal Neoplasms/pathology , Adenosarcoma/complications , Adenosarcoma/therapy , Combined Modality Therapy , Diagnosis, Differential , Female , Humans , Hysterectomy/methods , Middle Aged , Mixed Tumor, Mullerian/complications , Mixed Tumor, Mullerian/therapy , Neoplasm Recurrence, Local , Reoperation , Treatment Outcome , Uterine Neoplasms/complications , Uterine Neoplasms/therapy , Uterine Prolapse/complications , Uterine Prolapse/pathology , Uterine Prolapse/surgery , Vaginal Neoplasms/complications , Vaginal Neoplasms/therapyABSTRACT
An eleven year old boy presented with localized swelling of the left calf which had been developing for more than 5 years. Another smaller mass was found in the pretibial area. There was an invincible equinus deformity of the foot. Surgical biopsies revealed characteristic histological features of focal myositis showing necrotic and regenerating muscle fibers, randomly distributed, with inflammatory infiltration. An intense fibrotic reaction was observed. This constitutes to our knowledge the first reported case of focal myositis in which development of muscle sclerosis was so important that it was necessary to perform tenotomies one year after excision of the principal tumor in order to restore normal gait. A nearly two-years follow-up does not give evidence of recurrent lesion.
Subject(s)
Leg , Muscle Neoplasms/diagnosis , Myositis/diagnosis , Achilles Tendon/surgery , Adrenal Cortex Hormones/therapeutic use , Arthrodesis/methods , Child , Diagnosis, Differential , Follow-Up Studies , Foot/surgery , Humans , Magnetic Resonance Imaging , Male , Muscle Neoplasms/therapy , Myositis/therapy , PrognosisABSTRACT
We report a case of pseudo-tumoral pulmonary amyloidosis in which the diagnosis was achieved by a transbronchial biopsy and ultimately confirmed by a necropsy examination of the lung. The lung disorder was isolated without any co-existing disturbance of the immunological system.
Subject(s)
Amyloidosis/pathology , Lung Diseases/pathology , Aged , Humans , MaleABSTRACT
Chorangioma, one of the most frequent placental tumors, is associated with an important perinatal morbidity and mortality. We describe the case of a pregnant woman in whom this tumor was diagnosed during a routine obstetric investigation. The originality of our report is a strong and clear correlation between echographic, radiologic and histopathological findings. To avoid its obstetric and perinatal dramatic complications, we review the main echographic patterns allowing an early diagnosis of chorangioma.
