Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 1 de 1
Filter
Add more filters










Database
Type of study
Language
Publication year range
1.
Eksp Klin Gastroenterol ; (3): 31-3, 2015.
Article in Russian | MEDLINE | ID: mdl-26281174

ABSTRACT

One of the most likely causes of the lack of effectiveness of eradication therapy of peptic ulcer associated with Helicobacter pylori, is a feature of omeprazole metabolism by cytochrome CYP2C19. The paper work presents evidence that the rate of reduction of the clinical picture and the likelihood of scarring ulcers and eradication rates higher in patients slow metabolizers of omeprazole.


Subject(s)
Cytochrome P-450 CYP2C19 , Genotype , Helicobacter Infections , Helicobacter pylori , Omeprazole , Proton Pump Inhibitors , Cytochrome P-450 CYP2C19/genetics , Cytochrome P-450 CYP2C19/metabolism , Female , Helicobacter Infections/drug therapy , Helicobacter Infections/enzymology , Helicobacter Infections/genetics , Humans , Male , Middle Aged , Omeprazole/administration & dosage , Omeprazole/pharmacokinetics , Peptic Ulcer/drug therapy , Peptic Ulcer/enzymology , Peptic Ulcer/genetics , Peptic Ulcer/microbiology , Proton Pump Inhibitors/administration & dosage , Proton Pump Inhibitors/pharmacokinetics
SELECTION OF CITATIONS
SEARCH DETAIL
...