ABSTRACT
Coronavirus is a source of deep venous thrombosis (DVT) due to complications such as over-coagulation, blood stasis, and endothelial damage. Ovarian vein thrombosis (OVT) is a very serious and rare disease. In this study, we report tow rare case of women with coronavirus who were hospitalized with a right ovarian vein thrombosis mimicking acute abdomen who progressed well on anticoagulation. Our report adds further document in Side effects and rare localisation of obstruction of veins and arteries in patient with corona virus.
Subject(s)
Abdomen, Acute , COVID-19/complications , Enoxaparin/administration & dosage , Ovary/blood supply , Puerperal Disorders , Venous Thrombosis , Abdomen, Acute/diagnosis , Abdomen, Acute/etiology , Adult , Anticoagulants/administration & dosage , COVID-19/blood , COVID-19/diagnosis , COVID-19/physiopathology , COVID-19/therapy , Diagnosis, Differential , Female , Fibrin Fibrinogen Degradation Products/analysis , Humans , Male , Middle Aged , Puerperal Disorders/blood , Puerperal Disorders/etiology , Puerperal Disorders/physiopathology , Puerperal Disorders/therapy , SARS-CoV-2/isolation & purification , Tomography, X-Ray Computed/methods , Treatment Outcome , Veins/diagnostic imaging , Veins/pathology , Venous Thrombosis/blood , Venous Thrombosis/etiology , Venous Thrombosis/physiopathology , Venous Thrombosis/therapy , Post-Acute COVID-19 SyndromeABSTRACT
In this paper, we report two cases of induced thrombocytopenia after the infusion of glycoprotein (GP) IIb/IIIa receptors antagonists, following a coronary angioplasty. The first patient is a 65-year-old woman, admitted with acute coronary syndrome requiring percutaneous angioplasty with stenting. The patient was given tirofiban + unfractionated heparin (UFH). Ten hours later, the patient revealed very severe thrombocytopenia and went into hemorrhagic shock (hematemesis and hematoma at the injection site). The patient was transfused with nine units of red blood cells (RBCs), 24 platelets pellets and 4 units of fresh frozen plasma (FFP). The second patient is a 76-year-old woman. She was admitted to hospital for acute coronary syndrome necessitating percutaneous angioplasty with stenting and a glycoprotein IIb/IIIa receptor antagonists, tirofiban + unfractionated (UFH). Four hours later, the patient presented with gingivorrhagia associated thrombocytopenia. She received six platelet pellets transfusion with well clinical and biological improvement. These two observations raise the significance of a close monitoring of platelet count after the initiation of GP IIb/IIIa antagonists infusion, which are sometimes responsible for life-threatening adverse events.
Subject(s)
Platelet Aggregation Inhibitors/adverse effects , Platelet Glycoprotein GPIIb-IIIa Complex/antagonists & inhibitors , Thrombocytopenia/chemically induced , Tirofiban/adverse effects , Aged , Angioplasty, Balloon, Coronary , Anticoagulants/administration & dosage , Anticoagulants/adverse effects , Female , Heparin/administration & dosage , Heparin/adverse effects , Humans , Plasma , Platelet Aggregation Inhibitors/administration & dosage , Platelet Transfusion , Thrombocytopenia/therapy , Tirofiban/administration & dosageABSTRACT
Hypertrophic cardiomyopathy is a primary muscle disorder characterized by an abnormal thickness of the left ventricular wall. It is often going undiagnosed because many patients have few symptoms and can lead normal lives. This is a case report about an apical cardiomyopathy diagnosed at a very late stage in an old amateur soccer player. He was hospitalized due to acute chest pain; neurologic disorder related to a hypertensive emergency, he underwent successful percutaneous coronary intervention, echocardiography and CMR revealed Apical hypertrophic cardiomyopathy. The development of sports cardiology has major importance in the detection of cardiac disease which may have poor prognosis. Our patient had the chance to achieve his entire career without rhythmic complications.
Subject(s)
Cardiomyopathy, Hypertrophic , Soccer , Cardiomyopathy, Hypertrophic/diagnosis , Chest Pain/etiology , Echocardiography , Electrocardiography , Heart Ventricles , Humans , MaleABSTRACT
Coronavirus disease 2019 (COVID-19) has been reported as the possible cause of acute myocarditis. Myocarditis is an inflammatory heart disease mostly caused by viral infections. Cytomegalovirus (CMV) primary infection is often not suspected as a cause of myocarditis in immune-competent adults. We report the case of a 37-year-old male admitted with fever, cough and dyspnea. Chest CT showed typical ground-glass changes indicative of viral pneumonia. He was tested negative for COVID-19 but had biological markers that made us still suspect it. He had elevated troponin I level (up to 111.5 ng/mL) and diffuse myocardial dyskinesia along with a decreased left ventricular ejection fraction (LVEF). He was diagnosed with CMV myocarditis with cardiac insufficiency and totally recovered without antiviral therapy. During the COVID-19 pandemic patients may develop myocarditis, still every myocarditis is not a COVID infection. Myocarditis linked to CMV infection may be rare, but life-threatening.
