Association between lung function and dyspnoea and its variation in the multinational Burden of Obstructive Lung Disease (BOLD) study.

BACKGROUND: Dyspnoea is a common symptom of respiratory disease. However, data on its prevalence in general populations and its association with lung function are limited and are mainly from high-income countries. The aims of this study were to estimate the prevalence of dyspnoea across several world regions, and to investigate the association of dyspnoea with lung function. METHODS: Dyspnoea was assessed, and lung function measured in 25,806 adult participants of the multinational Burden of Obstructive Lung Disease study. Dyspnoea was defined as ≥2 on the modified Medical Research Council (mMRC) dyspnoea scale. The prevalence of dyspnoea was estimated for each of the study sites and compared across countries and world regions. Multivariable logistic regression was used to assess the association of dyspnoea with lung function in each site. Results were then pooled using random-effects meta-analysis. RESULTS: The prevalence of dyspnoea varied widely across sites without a clear geographical pattern. The mean prevalence of dyspnoea was 13.7 % (SD=8.2 %), ranging from 0 % in Mysore (India) to 28.8 % in Nampicuan-Talugtug (Philippines). Dyspnoea was strongly associated with both spirometry restriction (FVC

Tuberculosis awareness in Gezira, Sudan: knowledge, attitude and practice case-control survey.

This case-control study aimed to assess tuberculosis (TB) awareness and its associated sociodemographic characteristics in Gezira, Sudan. New smear-positive TB patients registered in Gezira in 2010 (n = 425) and age-matched controls who attended the same health facilities for other reasons (n = 850) formed the study sample. Awareness was measured using a modified standard World Health Organization TB knowledge, attitude and practice instrument. There was no significant difference between TB cases and the controls in overall levels of TB awareness. About two-thirds of TB cases and controls had good TB awareness. Respondents' sex was associated with awareness among the controls. Age, level of education, type of residence and type of occupation were significantly associated with TB awareness, whereas marital status had no effect. The good level of TB awareness found among TB cases and controls is a baseline for further TB awareness-raising among the Gezira population.

Tuberculosis awareness in Gezira, Sudan:knowledge, attitude and practice case-control survey

This case control study aimed to assess tuberculosis [TB]awareness and its associatedsociodemographic characteristics in Gezira, Sudan.New smear-positive TB patients registered in Gezira in 2010 [n - 425]and age-matched controls who attended the same health facilities for other reasons [n = 850]formed the study sample.Awareness was measured using a modified standard World Health Organization TB knowledge, attitude and practice instrument.There was no significant difference between TB cases and the controls in overall levels of TB awareness.About two-thirds of TB cases and controls had good TB awareness.Respondents' sex was associated with awareness among the controls.Age, level of education, type of residence and type of occupation were significantly associated with TB awareness, whereas marital status had no effect.The good level of TB awareness found among TB cases and controls is a baseline for further TB awareness-raising among the Gezira population

تهدف دراسة الحالات والشواهد هذه إلى تقييم مدى الوعي بالسل، والسمات الاجتماعية والديموغرافية المصاحبة له في الجزيرة بالسودان. واعتمدت عينة الدراسة على مرضى السل الجدد إيجابيي اللطاخة المسجلين في ولاية الجزيرة بالسودان في عام 2010 [العدد = 425]والشواهد الذين يضاهون الحالات في السن ممن حضروا إلى المرافق الصحية نفسها لأسباب أخرى [العدد = 850]. وتم قياس مدى الوعي باستخدام المقياس المعدل لمنظمة الصحة العالمية لقياس المعارف والمواقف والممارسات. ولم يكن هناك أي فروق يعتد بها بين حالات السل والشواهد من حيث المستوى الكلي للوعي بالسل. ولقد اتضح أن ثلثي حالات السل والشواهد لديها مستوى جيد من الوعي بالسل. وأن جنس المستجيب للدراسة يؤثر على مدى الوعي بين الشواهد. فالسن، ومستوى التعليم ونمط الإقامة ونوع المهنة كلها من الأمور التي ترتبط بشكل كبير بمدى الوعي بالسل، في حين نجد أن الحالة الزواجية لم يكن لها أي أثر. ومن ثم فإن مستوى الوعي الجيد بالسل لدى الحالات المصابة به ولدى الشواهد تمثل خط الأساس لإذكاء المزيد من الوعي بالسل لدى سكان ولاية الجزيرة

La présente étude cas-témoin visait à évaluer la sensibitisation à la tubercutose et les caractéristiques sociodémographiques associées dans l'état de Gézira [Soudan]. L'échantillon de l'étude était compose de nouveaux patients a frottis positifs pour la tuberculose au Gézira en 2010 [n = 425]et de témoins appariés pour l'âge qui consultaient dans les mêmes établissements de santé pour d'autres motifs [n = 850]. Le degré de sensibilisation à la maladie a été mesuré à l'aide de l'instrument standard modifié de l'Organisation mondiale de la Santé évaluant les connaissances, les attitudes et les pratiques en matière de tuberculose.Aucune différence significative n'a été observée entre les patients tuberculeux et les témoins dans les niveaux généraux de sensibilisation à la tuberculose.Environ deux tiers des patients tuberculeux et des témoins avaient un niveau de sensibilisation à la tuberculose satisfaisant.Dans le groupe des témoins, les hommes et les femmes n'avaient pas le même niveau de sensibilisation à la question.L'âge, le niveau d'études, le type de résidence et la profession étaient des facteurs nettement corrélés à la sensibilisation à la tuberculose, contrairement à la situation matrimoniale.Le niveau satisfaisant de sensibilisation à la tuberculose observé chez les patients atteints de tuberculose est un point de départ pour l'augmentation de la sensibilisation à cette maladie dans la population du Gézira