1.
Life Sci
; 33(13): 1285-94, 1983 Sep 26.
Article
in English
| MEDLINE
| ID: mdl-6350781
ABSTRACT
The influence of mefloquine and additional antimalarial drugs on (3H)adenosine uptake, macromolecular synthesis, and cell stability was determined in rodent red cells parasitized with Plasmodium berghei. High arylmethanol to cell ratios induced lysis, whereas inhibition of macromolecular synthesis occurred at lower drug/cell ratios. A 2-acetylpyridine thiosemicarbazone rapidly suppressed (3H)adenosine uptake, and also blocked macromolecular synthesis by parasitized cells.
Subject(s)
Erythrocytes/parasitology , Nucleic Acids/biosynthesis , Phenanthrenes/pharmacology , Plasmodium berghei/physiology , Quinolines/pharmacology , Thiosemicarbazones/pharmacology , Adenosine/metabolism , Animals , Antimalarials/pharmacology , Erythrocytes/drug effects , Erythrocytes/physiology , Macromolecular Substances , Mefloquine , Plasmodium berghei/drug effects , Rats , Reticulocytes/parasitology
2.
Clin Chem
; 18(11): 1318-22, 1972 Nov.
Article
in English
| MEDLINE
| ID: mdl-4652828
Subject(s)
Erythrocytes/analysis , Glyceric Acids/blood , Autoanalysis , Colorimetry , Glycolates , Humans , Hypoxia/blood , Methods , Organophosphorus Compounds/blood , Phosphotransferases
3.
Ann Clin Lab Sci (1971)
; 2(5): 383-8, 1972.
Article
in English
| MEDLINE
| ID: mdl-4343279
Subject(s)
Glycerophosphates/blood , Autoanalysis , Blood Chemical Analysis/standards , Blood Preservation , Cyclohexanes , Drug Stability , Evaluation Studies as Topic , Fluorometry , Freezing , Glyceraldehyde-3-Phosphate Dehydrogenases , Humans , Hydrazones/analysis , Methods , NAD/analysis , Oxidation-Reduction , Phosphoglycerate Kinase , Phosphopyruvate Hydratase , Phosphotransferases , Pyruvate Kinase , Quaternary Ammonium Compounds , Spectrophotometry , Time Factors
4.
Proc Soc Exp Biol Med
; 138(2): 536-41, 1971 Nov.
Article
in English
| MEDLINE
| ID: mdl-5118462
Subject(s)
Endotoxins/pharmacology , Histamine/pharmacology , Shock, Septic/enzymology , Alanine Transaminase/blood , Analysis of Variance , Animals , Aspartate Aminotransferases/blood , Blood Pressure/drug effects , Blood Protein Electrophoresis , Creatine Kinase/blood , Dogs , Isocitrate Dehydrogenase/blood , Isoenzymes/blood , L-Lactate Dehydrogenase/blood , Sodium Chloride/pharmacology , Time Factors
5.
Surgery
; 64(3): 622-8, 1968 Sep.
Article
in English
| MEDLINE
| ID: mdl-4877693
