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Contemp Clin Trials ; 48: 99-109, 2016 05.
Article in English | MEDLINE | ID: mdl-27091813

ABSTRACT

OBJECTIVES: African American and Hispanic elderly are at elevated risk of both depression and cardiovascular disease, relative to non-Hispanic whites. Effective interventions are therefore needed to address depressive symptoms and to reduce these disparities. BRIGHTEN Heart was a behavioral randomized controlled trial to test the efficacy of a virtual team intervention in reducing depressive symptoms in minority elderly as measured by the 9-item Patient Health Questionnaire (PHQ9). STUDY DESIGN: 250 African American and Hispanic adults, age ≥60 years, with comorbid depression and overweight/obesity were randomized. Participants randomized to the Intervention condition received a social work evaluation, team-based electronic consultation, case management, and psychotherapy over a 12 month period. Control participants were enrolled in a membership program that provided health classes and other services to support chronic disease self-management. Blinded research assistants completed assessments at baseline, and 6 and 12 months postrandomization. RESULTS: The study population was characterized by low socioeconomic status, with 81.4% having a household income of less than $20,000. Although median depression scores were in the mild range, 25% of participants had scores showing moderate to severe depression at baseline. 75% of participants had four or more chronic conditions. Significant demographic and clinical differences were observed between the African American and Hispanic populations. CONCLUSIONS: BRIGHTEN Heart was designed to rigorously test the efficacy of a multi-level intervention to reduce comorbid depressive symptoms and cardiovascular risk in minority elderly. Investigators successfully recruited a cohort well suited to testing the study hypothesis.


Subject(s)
Black or African American , Depression/therapy , Hispanic or Latino , Obesity/epidemiology , Primary Health Care , Psychotherapy , Aged , Aged, 80 and over , Cardiovascular Diseases/epidemiology , Comorbidity , Depression/epidemiology , Female , Humans , Male , Middle Aged , Minority Groups , Multiple Chronic Conditions , Overweight/epidemiology , Patient Care Management , Patient Care Team , Patient Health Questionnaire , Poverty , Social Class
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