ABSTRACT
To accomplish the assessment and treatment of abstinence in the infant of the drug dependent mother, a scoring system has been devised for use as a clinical and research tool. The score monitors the passively addicted infant in a more comprehensive and precise way than has previously been described, and permits us to be more objective in our clinical estimates of the abstinence syndrome. Further, this scoring system has been used by relating it to the dosage schedule of phenobarbital or paregoric as part of an ongoing research project designed to test the comparative usefulness of recommended treatments for neonates with abstinence symptoms. It has been found useful also in following the progression or diminution of symptomatology before, during and after drug therapy. Moreover, the scoring system provides a basis for developing uniform criteria for the assessment and treatment of the neonate of the addicted mother.
Subject(s)
Infant, Newborn, Diseases , Substance Withdrawal Syndrome , Substance-Related Disorders , Clinical Trials as Topic , Female , Humans , Infant, Newborn , Infant, Newborn, Diseases/diagnosis , Infant, Newborn, Diseases/drug therapy , Opium/therapeutic use , Phenobarbital/therapeutic use , Pregnancy , Pregnancy Complications , Substance Withdrawal Syndrome/diagnosis , Substance Withdrawal Syndrome/drug therapy , Substance-Related Disorders/complications , Sucking BehaviorABSTRACT
A scoring system for the neonatal abstinence syndrome has been devised and implemented as both a clinical and investigative tool. The score monitors the passively addicted infant in a more comprehensive and objective fashion, and facilitates a more precise evaluation of the clinical status of the infant undergoing withdrawal. In addition, the scoring system has been applied in research designed to test the comparative usefulness of various pharmacologic agents currently recommended for the neonatal abstinence syndrome, and has been found useful in following the progression and diminution of withdrawal symptomatology before, during, and after therapy. Furthermore, the scoring system provides a basis ofr developing uniform criteria for the assessment and treatment of the neonate born to the addicted mother.
Subject(s)
Heroin Dependence/complications , Infant, Newborn, Diseases/drug therapy , Pregnancy Complications , Psychometrics , Substance Withdrawal Syndrome/drug therapy , Administration, Oral , Antidiarrheals/administration & dosage , Central Nervous System/drug effects , Diazepam/administration & dosage , Diazepam/therapeutic use , Digestive System/drug effects , Female , Humans , Infant, Newborn , Infant, Newborn, Diseases/diagnosis , Infant, Newborn, Diseases/etiology , Injections, Intramuscular , Opium/therapeutic use , Phenobarbital/administration & dosage , Phenobarbital/therapeutic use , Pregnancy , Substance Withdrawal Syndrome/diagnosis , Substance Withdrawal Syndrome/etiology , Sucking Behavior/drug effectsSubject(s)
Heroin Dependence/therapy , Infant, Newborn, Diseases/therapy , Infant, Premature, Diseases/therapy , Pregnancy Complications/therapy , Administration, Oral , Anesthesia, Conduction , Anesthesia, Obstetrical , Birth Weight , Counseling , Female , Fetal Death , Humans , Infant Mortality , Infant, Newborn , Methadone/administration & dosage , Methadone/therapeutic use , Pregnancy , Pregnancy Complications/epidemiology , Prenatal Care , Substance Withdrawal Syndrome/drug therapy , Substance Withdrawal Syndrome/therapyABSTRACT
PIP: The victim of sexual assault has 5 needs: 1) care of injuries, 2) prevention of venereal disease, 3) prevention/alleviation of psychologic damage, 4) medicolegal examination with documentation for law enforcement authorities, and 5) prevention of pregnancy. The staff of Philadelphia General Hospital, in a program designed to meet these needs, treated 480 (24.6 per 100,000 population) victims of sexual assault in 1968. 70% were ages 14-44, 24% below 14 years of age. In this program, serologic testing and cultures are followed by intramuscular injection of penicillin, 2,400,000 units. Both pediatric and adult victims are treated with reassurance, close follow-up and psychiatric referral as indicated. Detection of motile spermatozoa by examination of vaginal aspirate by a qualified experienced laboratory technician is of utmost importance. Postcoital contraceptive therapy revealed a high incidence of gastrointestinal side effects and 4 pregnancies were established in the treated cycle.^ieng