Serologic Prevalence of Ebola Virus in Equatorial Africa.

We conducted a serologic survey of 2,430 serum samples collected during 1997-2012 for various studies to determine the prevalence of the hemorrhagic fever virus Ebola virus (EBOV) in equatorial Africa. We screened serum samples for neutralizing antibodies by using a pseudotype microneutralization assay and a newly developed luciferase immunoprecipitation system assay. Specimens seroreactive for EBOV were confirmed by using an ELISA. Our results suggest a serologic prevalence of 2%-3.5% in the Republic of the Congo and the Democratic Republic of the Congo, which have reported outbreaks of infection with EBOV. In addition we detected a seroprevalence of 1.3% in southern Cameroon, which indicated a low risk for exposure in this region.

Time-resolved torsional relaxation of spider draglines by an optical technique.

The sensitivity of the torsional pendulum demonstrates the self-shape-memory effect in different types of spider draglines. Here we report the time-resolved noncovalent bonds recovery in the protein structure. The torsional dynamics of such multilevel structure governed by reversible interactions are described in the frame of a nested model. Measurement of three different relaxation times confirms the existence of three energy storage levels in such two protein spidroin systems. Torsion opens the way to further investigations towards unraveling the tiny torque effects in biological molecules.

Rabi-Lorentzian profile of an atomic resonance obtained with Gaussian beams.

We demonstrate that the interaction between atoms and a Gaussian beam changes the Lorentzian resonance into a so-called Rabi-Lorentzian resonance profile. The existence of such profiles is experimentally evidenced in a dark resonance situation for metastable (4) He, in the absence of any external perturbation. A topological mechanism is shown theoretically to account for the measured profiles. We observe a 3% systematic residual with respect to a pure Lorentzian profile, which could play a role in the search of high precision in the measurement of fundamental constants.

Measurement of positive and negative Goos--Hänchen effects for metallic gratings near Wood anomalies.

Large Goos-Hänchen effects are isolated for reflection on a metallic grating. These shifts occur in the vicinity of Wood anomalies. Depending on the nature of the anomaly, these displacements are found to be either positive or, contrary to the usual GH effect, clearly negative. Those shifts, associated with forward and backward leaky surface waves, are as large as plus or minus tens of wavelengths for a classic metallic grating.

Direct measurement of the wigner delay associated with the goos-Hanchen effect

It is shown experimentally that the nonspecular reflection of light on an interface induces a time delay, as predicted by Wigner's scattering theory. A differential femtosecond technique is used to directly isolate this delay, associated with the Goos-Hanchen spatial shift produced by a grating near a resonant Wood anomaly. A delay of 4.4 fs is observed between TE and TM pulses, in agreement with the expected Wigner delay obtained from phase shift dispersion measurements.

Temporal behavior of an unstable optical cavity.

The relaxation of a geometrically unstable Fabry-Perot cavity is theoretically and experimentally investigated. It is observed that the usual sum of the exponential decays of the intensities in the different transverse modes of the cavity is replaced by a more complex behavior. In particular, light couplings into the fundamental mode of the cavity with initial wave excitation factors larger than unity, i.e., larger than in the case of mode-matched injection, are directly observed. The influence of the cavity Fresnel number and of transverse mode crossings and anticrossings on these cavity decays is isolated.

Self-mode-locked pulsed monomode laser.

We predict the existence of a new pulsed-laser operation regime, when the phases and polarizations of the two coupled cold-cavity eigenstates of a monomode solid-state laser are taken into account in the derivation of the Maxwell-Bloch equations. This monomode pulsed regime is experimentally observed, without any normal mode locking or Q switching occurring inside the cavity. We obtain close agreement between experiments and theory, even in the simple case of a Nd:YAG microchip laser, for which sech(2) pulses at nearly megahertz repetition rates are readily observed.

Rotating polarization imaging in turbid media.

It is shown experimentally that one can image an object embedded in a turbid medium by probing the medium with light with a rotating linear polarization. This method permits the ballistic photons to be isolated from the large background of photons that have been multiply scattered by optically dense anisotropic scatterers. This technique achieves a good signal-to-noise ratio even with a low-power continuous laser, leading to images with a diffraction-limited resolution comparable with that obtained in optically homogeneous media.