ABSTRACT
Percutaneous, catheter-mediated lysis was performed on 56 patients with acute to subacute thrombosis of the superficial femoral artery (Fontaine stage IIb to IV). One half of the patients received rt-PA, the other half urokinase. The clinical parameters of the two groups of patients were largely the same. The therapeutical results were, at about the same treatment costs, better in the rt-PA patients group, in particular with regard to the considerably shorter average treatment period, which lasted on the average for 2 hours in the rt-PA group, vs. 6 hours in the urokinase group. The recanalisation rate was also higher in the rt-PA group (86%) vs. 75% in the urokinase group.
Subject(s)
Femoral Artery , Thrombolytic Therapy/methods , Thrombosis/drug therapy , Tissue Plasminogen Activator/therapeutic use , Urokinase-Type Plasminogen Activator/therapeutic use , Aged , Aged, 80 and over , Catheterization, Peripheral/methods , Drug Evaluation , Femoral Artery/diagnostic imaging , Humans , Middle Aged , Popliteal Artery/diagnostic imaging , Radiography, Interventional , Recombinant Proteins/therapeutic use , Thrombosis/diagnostic imagingABSTRACT
For a sample of 8 men and 3 women, 47-80 years old, closed-eye-EEGs were registered for the first time in the morning before hemofiltration treatment, again thereafter at 1 p.m., and a third time at 7 p.m. The day after treatment EEG-registrations were conducted at the same times. Apart from traditional visual evaluation every EEG was recorded on tape for computer processing. Simultaneously with every EEG-registration the body temperature was measured. For comparison served corresponding data of 17 hemodialysis patients, and of 10 healthy old and 12 healthy young volunteers. The peak-frequency of the hemofiltration patients turned out significantly slower than that of the healthy persons and of the hemodialysis patients. While in the healthy volunteers the peak-frequency increased corresponding with the body temperature from the morning to the evening, the hemofiltration patients lacked such a correlation, although their temperature ascended in the normal way. As to the circadian variations of the activity in the diverse frequency-bands, the hemofiltration patients, and to a less degree the hemodialysis patients, showed especially in the day after treatment distinct deviations from the healthy volunteers.
