1.
Org Biomol Chem
; 13(8): 2255-9, 2015 Feb 28.
Article
in English
| MEDLINE
| ID: mdl-25588099
ABSTRACT
Natural product discovery arises through a unique interplay between chromatographic purification and biological assays. Currently, most techniques used for natural product purification deliver leads without a defined biological action. We now describe a technique, referred to herein as functional chromatography, that deploys biological affinity as the matrix for compound isolation.