ABSTRACT
Metastases from urologic neoplasms often occur to the central nervous system or surrounding bony structures. Usually these metastases are discovered after the primary tumor has been identified. However, these tumors may present primarily with only manifestations of their central nervous system metastases. Five cases of different urologic tumors presenting as neurosurgical masses are presented, along with a brief review of the pertinent literature.
Subject(s)
Brain Neoplasms/secondary , Skull Neoplasms/secondary , Spinal Neoplasms/secondary , Urologic Neoplasms/diagnosis , Adult , Aged , Humans , Male , Middle AgedABSTRACT
The association of nodular renal blastema, renal dysplasia and duplicated collecting systems may represent more than a histopathological observation. Based on the "double hit" theory of oncogenesis, the appearance of this histologic pattern in kidneys with other developmental alterations may account for an increased risk of neoplasia.
