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1.
Article in English | MEDLINE | ID: mdl-23888231

ABSTRACT

Patients with heart failure symptoms due to ischemic cardiomyopathy face a poor prognosis without adequate treatment. In these patients with viable ischemic myocardium, revascularization surgery is not a new but an established treatment concept. the CASS study, published in 1983, was already able to document the superiority of coronary artery revascularization in patients with poor left ventricular function. It is of utmost importance to predict regional functional recovery in order to assess viability and, thus, the indication for revascularization. Late gadoliniium enhancement cardiovascular magnetic resonance is the new gold standard. By applying this technique, it can be demonstrated that the transmural extent of a scar predicts segmental functional recovery. Numerous studies describe the predictors of survival of surgical revascularization, the indication and impact of medical antiarrhythmic treatment or choice of graft. In addition to conventional surgery, off-pump procedures, minimal extracorporeal circulation and hybrid revascularization have a special role in the treatment of patients with ischemic cardiomyopathy. Surgical techniques and medical therapies continue to improve. The future revascularization in these patients will focus on improving results and making coronary artery bypass grafting for elective revascularization less invasive and safer. Technical evolution, including the use of robotics and anastomotic connectors, intraoperative imaging and protein enzyme therapies, have to be defined concerning their special impact in these patients.

2.
Pathologe ; 34(4): 343-6, 2013 Jul.
Article in German | MEDLINE | ID: mdl-23306533

ABSTRACT

Within a few months a 31-year-old female patient was diagnosed with a psammomatous melanotic schwannoma, an atrial myxoma and microfollicular adenomas in both thyroid lobes. Therefore, sufficient diagnostic criteria of a Carney complex were fulfilled. The Carney complex is an inherited autosomal dominant disorder with highly variable phenotypes, which was initially described by Carney in 1985 as a complex of myxomas, spotty skin pigmentation and endocrine overactivity. Pathologists should consider this differential diagnosis in reports when confronted with a psammomatous melanotic schwannoma.


Subject(s)
Adenoma/pathology , Carney Complex/pathology , Heart Neoplasms/pathology , Myxoma/pathology , Neoplasms, Multiple Primary/pathology , Neurilemmoma/pathology , Thyroid Neoplasms/pathology , Adenoma/genetics , Adult , Carney Complex/genetics , Cyclic AMP-Dependent Protein Kinase RIalpha Subunit/genetics , DNA Mutational Analysis , Diagnosis, Differential , Female , Head and Neck Neoplasms/genetics , Head and Neck Neoplasms/pathology , Heart Atria/pathology , Heart Neoplasms/genetics , Humans , Myxoma/genetics , Neoplasms, Multiple Primary/genetics , Neurilemmoma/genetics , Phenotype , Signal Transduction/genetics , Thyroid Gland/pathology , Thyroid Neoplasms/genetics
3.
Article in English | MEDLINE | ID: mdl-23439278

ABSTRACT

In coronary artery surgery the superiority of the internal mammary artery graft in 10-year survival was documented in 1986. In 1999 it was demonstrated that death, reoperation and percutaneous transluminary coronary angioplasty were more frequent in patients undergoing single rather than bilateral internal mammary artery grafting. Today coronary artery bypass grafting surgery is challenged by the success story of modern interventional cardiology. The Syntax Study, however, clearly underlined the better outcome for patients with triple-vessel and/or left main disease undergoing coronary artery bypass grafting in terms of repeat revascularization. Another point of ongoing discussion is the comparison between on-pump and off-pump coronary artery revascularization techniques. Even if mixed results exists in the literature, in experienced hands the combination of aortic no-touch and total arterial revascularization, probably leads to the superiority in off pump coronary artery bypass grafting in terms of significantly decreased rates of mortality, stroke, major adverse cardiac and cerebral vascular events. Coronary artery surgery in the next decade will be influenced by the further progression of minimally invasive surgical principles and by a variety of other factors. The role of robotics and hybrid surgery has yet to be defined. Alternatives within surgery will not only need to move to a less disruptive strategy (e.g. from on-pump to off-pump bypass) but also have to secure sustained innovation, as we can be sure that the current coronary artery bypass grafting activity will change substantially.

4.
Article in English | MEDLINE | ID: mdl-23439488

ABSTRACT

With an incidence rate of 1-4%, mediastinitis following cardiac surgery is a rarely occurring complication, but may show a mortality rate of up to 50%. Risk factors for sternal instability are insulin-dependent diabetes mellitus, obesity, immunosuppressed state, chronic obstructive pulmonary disease, osteoporosis, history of radiation, renal failure, body height, smoking and nutritional state. The aim of this paper is to show an overview of this clinical picture, present the risk factors and elucidate the therapy options chronologically. As a result of interdisciplinary cooperation, a therapy concept has developed which is adapted to the patient individually. Therapy begins with the simplest measures and, if deemed necessary, this is then escalated step by step. The aim of the treatment is to bring the infection under control, which requires radical surgical debridement, removal of infected and necrotic tissue, removal of all foreign bodies (including wires and osteosynthesis material) and the removal of all infected, necrotic osseous material if necessary followed by vacuum-assisted closure therapy. The reconstruction of defects of the anterior chest wall is achievable using different muscle flaps. Mostly the muscle pectoralis major is used unilaterally or bilaterally with or without disinsertion of the tendon. Other options are the omental flap, the muscle latissimus dorsi flap or the muscle rectus abdominis flap. A combined approach comprising surgical debridement, short-term vacuum therapy and subsequent myoplastic coverage has proved successful and can be carried out with a high standard of safety.

5.
Article in English | MEDLINE | ID: mdl-23439732

ABSTRACT

The design of stentless valve prostheses is intended to achieve a more physiological flow pattern and superior hemodynamics in comparison to stented valves. First - generation stentless bioprosthesis were the Prima valve, the Freestyle valve and the Toronto stentless porcine valve. The second generation of stentless valves, as the Super stentless aortic porcine valve, need only one suture line. The Sorin Pericarbon Freedom and the Equine 3F heart Valve belong to the third generation of stentless valve pericardial bioprostheses. A stentless valve to replace a full root can be implanted by several surgical techniques: complete or modified subcoronary, root inclusion and full root. The full root technique is accompanied by the lowest incidence of patient-prothesis mismatch. Our own clinical experience reflects more than 3000 stentless valve implantations since April 1996. Randomized study trials showed a hemodynamic advantage for stentless valves, but several could not reach a significant level. Also reported was a significant advantage of stentless bioprostheses concerning transvalvular gradients, effective valve area and quicker regression of the left ventricular mass 6 months after the operation, but at 12 months. Advantages are obvious in patients with a decreased left ventricle ejection fraction of less than 50% and in smaller implanted valve size, concomitant aortic root pathology (e.g. dissection) and aortic valve endocarditis. A survival advantage for stentless bioprostheses in comparison to stented ones has been reported by all studies in the literature. Stentless valves enrich the surgical armamentarium. Time will define the place of stentless valves in the future.

6.
Zentralbl Chir ; 137(3): 257-61, 2012 Jun.
Article in German | MEDLINE | ID: mdl-22194084

ABSTRACT

BACKGROUND: Each and every hospital of any kind is forced, due to increased cost pressure, to work as economically and as efficiently as possible. This even applies when the operational orientations of the hospitals institutions are different. In the present article an analysis of the repercussions of the treatment of postoperative complications in terms of entrepreneurial practice is given. Our focus is on the opportunity cost. METHOD: A theoretical calculation of opportunity costs is made based on the example of postoperative infections following cardiac surgery and the resulting treatment. The bases of the examinations are the results collected at the hospital Mediclin Herzentrum Lahr / Baden in 2008. The wound healing disorders were recorded from November 2004 until November 2007 and include 3675 patients who were operated on using a median sternotomy. Out of the 3675 patients 45 (1.2 %) were affected. Various treatment options are at hand. The used therapy algorithm in our practice is dependent on the stage and the development of the infection. RESULTS: If the high trim point, the medial trim point and the low trim point of the mediastinitis patients, as well as the average revenue and the surcharge omission on exceeding the high trim point (these data can be found in the annual accounts) and knowledge of the actual length of stay of the mediastinitis patient are known, the opportunity cost, respectively potential turnover increases, can be calculated. Reducing the medial trim point from 48.43 to, for example, 36.37 days could potentially produce a turnover increase of as much as 10 633.41 €. CONCLUSION: Keeping patient safety in mind, significant turnover increases can be achieved with adequate planning. The considered sales situation, however, can only be achieved under the same terms: these being free operating room and bed capacities, available personnel, equal cost of materials as well as enough patients. The consideration of opportunity costs could be important for entrepreneurs if staff shortage continues and, in economical terms, non-expendable capacities are created.


Subject(s)
Cost-Benefit Analysis , Heart Diseases/economics , Heart Diseases/surgery , Hospital Costs/statistics & numerical data , Mediastinitis/economics , Postoperative Complications/economics , Sternotomy/economics , Surgical Wound Infection/economics , Diagnosis-Related Groups/economics , Entrepreneurship/economics , Female , Germany , Humans , Length of Stay/economics , Male , Mediastinitis/surgery , Models, Economic , National Health Programs/economics , Patient Care Planning/economics , Postoperative Complications/surgery , Reimbursement Mechanisms/economics , Surgical Wound Infection/surgery
7.
Thorac Cardiovasc Surg ; 59(8): 454-9, 2011 Dec.
Article in English | MEDLINE | ID: mdl-21544790

ABSTRACT

INTRODUCTION: We wanted to answer the question whether biological heart valves are inferior compared to mechanical heart valves in end-stage renal disease (ESRD) patients. METHODS: Between 01/1996 und 12/2006, 44 of 3293 patients undergoing aortic valve replacement (AVR) in a single institution suffered from dialysis-dependent ESRD and underwent a follow-up investigation after 1.9 years (median). Twelve (28.9 %) of these patients received a biological, 32 (71.1 %) of these patients a mechanical aortic valve prosthesis. To evaluate a possible influence of the valve type (biological/mechanical) on survival, uni- and multivariate logistic regression was used. RESULTS: ESRD patients after AVR had a relatively poor short-term (30-day mortality: 22.7 %) and long-term survival (median survival time: 24.7 months; 95 % CI: 0.2-47.7 months), irrespective of the type of heart valve prosthesis (hazard ratio for mortality depending on heart valve type in dialysis patients: 1.31, P = 0.400). Dialysis-dependent patients were not reoperated due to valve-related reasons. CONCLUSIONS: The long-term survival of dialysis-dependent patients after AVR is low (5-year survival: 29.5 %) irrespective of the type of heart valve prosthesis. Therefore, the use of biological AVR is not contraindicated in this group of patients.


Subject(s)
Aortic Valve Stenosis/surgery , Aortic Valve/surgery , Bioprosthesis , Heart Valve Prosthesis Implantation , Heart Valve Prosthesis , Kidney Failure, Chronic , Renal Dialysis , Aged , Analysis of Variance , Aortic Valve Stenosis/mortality , Female , Follow-Up Studies , Germany/epidemiology , Heart Valve Diseases/surgery , Heart Valve Prosthesis Implantation/methods , Heart Valve Prosthesis Implantation/mortality , Humans , Kidney Failure, Chronic/mortality , Kidney Failure, Chronic/therapy , Male , Middle Aged , Multivariate Analysis , Prognosis , Prosthesis Design , Prosthesis Failure , Survival Rate
8.
Thorac Cardiovasc Surg ; 59(1): 15-20, 2011 Feb.
Article in English | MEDLINE | ID: mdl-21243566

ABSTRACT

Poststernotomy mediastinitis following median sternotomy procedures such as open heart surgery is a rare complication which nevertheless has a mortality rate of up to 50 %. Several treatment options are currently available; however, none of them are standardized. Based on the experience gained from open heart surgery performed at the MediClin Heart Institute Lahr/Baden, a therapeutic algorithm was developed. The treatment steps consist of repeated radical surgical debridement, sternal restabilization, vacuum-assisted closure therapy (VAC) as well as a surgical reconstruction via M. pectoralis plasty (MPP). This approach had a 30-day mortality of 0 % and a hospital mortality of 10.4 %. The approach proved to be safe and advantageous for specific patient groups operated on at the MediClin Heart Institute Lahr/Baden.


Subject(s)
Bacterial Infections/complications , Mediastinitis/microbiology , Sternotomy/adverse effects , Surgical Wound Infection/microbiology , Aged , Algorithms , Anti-Bacterial Agents/therapeutic use , Bacterial Infections/diagnosis , Bacterial Infections/mortality , Bacterial Infections/therapy , Case-Control Studies , Debridement , Drainage , Female , Humans , Inpatients , Male , Mediastinitis/diagnosis , Mediastinitis/mortality , Mediastinitis/surgery , Mediastinitis/therapy , Negative-Pressure Wound Therapy/methods , Pectoralis Muscles/transplantation , Plastic Surgery Procedures/methods , Reference Standards , Reoperation , Risk Factors , Surgical Wound Infection/complications , Surgical Wound Infection/diagnosis , Surgical Wound Infection/mortality , Surgical Wound Infection/therapy , Survival Analysis , Treatment Outcome , Wound Healing
9.
Thorac Cardiovasc Surg ; 58(7): 403-7, 2010 Oct.
Article in English | MEDLINE | ID: mdl-20922623

ABSTRACT

INTRODUCTION: Female gender has been identified as an independent risk factor for perioperative mortality in several risk scores for cardiac surgery. Since no explanation has been given for this, this study aimed to evaluate potential differences in the distribution of other risk factors between the genders. PATIENTS AND METHODS: 10 714 consecutive coronary bypass patients were analyzed retrospectively. The distribution of the risk factors as used in the EuroSCORE was evaluated. Diabetes mellitus was added to the analysis as an additional risk factor. Patients aged between 60 and 70 years without any additional risk factors were directly compared in a subgroup analysis. Statistical analysis was done using the T-test or chi-square test where appropriate. RESULTS: Female patients were significantly older compared to male ones (69.1 ± 8.5 vs. 65.4 ± 4 years, P < 0.05). The distribution of the analyzed risk factors did not differ except for diabetes mellitus: female patients were more likely to present with diabetes (42 % vs. 29 %, P < 0.05) and in diabetic patients, the incidence of insulin dependency was higher in female patients (50 % vs. 33 %, P < 0.05). Overall perioperative mortality was higher in female patients (2.7 % vs. 1.8 %, P < 0.05). This difference increased when diabetes was present (3.9 % vs. 1.8 %, P < 0.05) and was even higher in insulin-dependent patients (4.9 % vs. 1.9 %, P < 0.05). However, when adjusting for age and diabetes, the differences were reduced. This was most evident when subgroups of age-adjusted patients without any additional risk factors were analyzed: no gender-specific difference in perioperative mortality was observed. CONCLUSIONS: Female gender itself did not present as an independent risk factor. The presence of diabetes mellitus increased the risk in female patients significantly more than in male patients. The higher prevalence of diabetes in female patients in combination with the older age at presentation might result in the higher overall mortality observed in female patients compared to men.


Subject(s)
Coronary Artery Bypass/mortality , Age Factors , Aged , Chi-Square Distribution , Diabetes Mellitus, Type 1/complications , Diabetes Mellitus, Type 1/mortality , Female , Germany , Hospital Mortality , Humans , Male , Middle Aged , Prevalence , Retrospective Studies , Risk Assessment , Risk Factors , Sex Factors , Time Factors , Treatment Outcome
10.
Dtsch Med Wochenschr ; 134 Suppl 6: S188-9, 2009 Oct.
Article in German | MEDLINE | ID: mdl-19834836

ABSTRACT

Annually about 100,000 acute cardiac deaths occur in Germany. For this reason, there is the obvious need, from a public health perspective, to inform the population about possible measures of their prevention and treatment. Ultimately every patient or admission referring doctor can be thought of as a recipient of "marketing". Other than within the context of economics, in medicine the subject of marketing is likely to produce a negative response. Any doctor engaging in marketing is quickly considered to be engaging in unfair competition at the expense of colleagues ("economic competitors"). However, despite some reservations it would seem sensible to provide transparency concerning the results of treatment. If the manner of competition is the right one, i.e. one that has as its aim to improve patient care, it can at the same time improve such care, motivate doctors and frequently also reduce costs. Transparency of the various aspects of improved medical care in this way represent a "pay-back" to everyone working in the health services. It is desirable to establish an external process of assessing any published data and, as far as possible, exclude all incorrect data from relevant measures of comparison. Competition can then be to the patient's benefit.


Subject(s)
Ethics, Medical , Moral Obligations , Cardiac Surgical Procedures/standards , Humans , New York , Risk Assessment , Thoracic Surgery/standards
11.
Dtsch Med Wochenschr ; 134 Suppl 6: S214-9, 2009 Oct.
Article in German | MEDLINE | ID: mdl-19834846

ABSTRACT

The strength of coronary bypass operations depends on the preservation of their benefits regarding freedom of symptoms, quality of life and survival, over decades. Significant variability of the results of an operative intervention according to the hospital or the operating surgeon is considered a weakness in the procedure. The external quality insurance tries to reach a transparent service providing market through hospital ranking comparability. Widely available information and competition will promote the improvement of the whole quality. The structured dialog acts as a control instrument for the BQS (Federal Quality Insurance). It is launched in case of deviations from the standard references or statistically significant differences between the results of the operations in any hospital and the average notational results. In comparison to the external control the hospital internal control has greater ability to reach a medically useful statement regarding the results of the treatment and to correct the mistakes in time. An online information portal based on a departmental databank (DataWarehouse, DataMart) is an attractive solution for the physician in order to get transparently and timely informed about the variability in the performance.The individual surgeon significantly influences the short- and long-term treatment results. Accordingly, selection, targeted training and performance measurements are necessary.Strict risk management and failure analysis of individual cases are included in the methods of internal quality control aiming to identify and correct the inadequacies in the system and the course of treatment. According to the international as well as our own experience, at least 30% of the mortalities after bypass operations are avoidable. A functioning quality control is especially important in minimally invasive interventions because they are often technically more demanding in comparison to the conventional procedures. In the field of OPCAB surgery, the special advantages of the procedure can be utilised to reach a nearly complete avoidance of postoperative stroke through combining the procedure with aorta no-touch technique. The long-term success of the bypass operation depends on the type of bypass material in additions to many other factors. Both internal mammary arteries are considered the most durable.Using an operation preparation check contributes to the operative success.


Subject(s)
Coronary Artery Bypass/methods , Coronary Artery Bypass/standards , Coronary Artery Bypass/mortality , Follow-Up Studies , Germany , Humans , Internet , Postoperative Complications/mortality , Postoperative Period , Quality Assurance, Health Care , Time Factors
12.
Dtsch Med Wochenschr ; 134 Suppl 6: S222-4, 2009 Oct.
Article in German | MEDLINE | ID: mdl-19834848

ABSTRACT

In Anesthesia, especially in Cardiac Anesthesia in germany exist a lots of standards, that define good quality. For external quality assurance and analysis there is a core data set defined with an extension for cardiac anesthesia for a survey of patient risk factors und complications. Because there is no obligation only a minority of hospitals take an active part and only few data exists. No external structures exist to initiate quality improvements in the participating hospitals. Furthermore there is no external quality assurance to address patient satisfaction. The German Association for Anaesthesiology and Intensive Care has established the requirements for external quality analysis. The hospitals should use these possibilities to prevent external specifications. Structures to fulfil the last step of the Demming Cycle (ACT) should be added.


Subject(s)
Anesthesia/standards , Cardiac Surgical Procedures/standards , Anesthesia/adverse effects , Anesthesia/methods , Blood Transfusion/standards , Cardiac Surgical Procedures/legislation & jurisprudence , Germany , Hospitals/standards , Humans , Monitoring, Physiologic/standards , Preoperative Care/standards , Quality Assurance, Health Care , Risk Factors
13.
Thorac Cardiovasc Surg ; 57(1): 18-21, 2009 Feb.
Article in English | MEDLINE | ID: mdl-19169991

ABSTRACT

INTRODUCTION: Platelet inhibition is thought to increase perioperative blood loss in patients with planned coronary artery bypass grafting (CABG). This retrospective study reviews the results of over 10 000 patients with CABG, comparing continued platelet inhibition with preoperative disruption of this therapy. PATIENTS AND METHODS: From 1995 to 2007, 12 023 patients underwent isolated CABG and were included in this study. The data were evaluated with regard to preoperative aspirin therapy, EuroScore relevant risk factors, and the operative results. Parameters of the operative outcome were in-hospital mortality, perioperative infarctions, reexploration rate, strokes, pericardial tamponade, blood transfusions, and perioperative drainage loss. RESULTS: The patients were divided into two groups: group A (continuous aspirin therapy till surgery [n = 2519]), and group B (patients with preoperative interruption of their aspirin therapy for at least five days [n = 9504]). There was no difference between the groups with regard to age, EuroScore (4.3 +/- 2.8 vs. 4.2 +/- 2.9), emergency cases (8.8 % vs. 8.7 %), left main stenoses (17.9 % vs. 17.6 %), duration of surgery (198 +/- 53 vs. 198 +/- 52 min.) and sex distribution. The postoperative drainage loss did not differ between groups A and B (834 +/- 781 ml vs. 902 +/- 811 ml), nor did the number of postoperatively administered red cell packages (0.88 +/- 2.7 vs. 1.01 +/- 2.9). When analyzing the three subgroups "on-pump primary CABG", "OPCAB procedures", and "redo CABG", again no difference was found in the main outcome parameters. Only the redo CABG of group B had a higher reexploration rate compared to group A (5 % vs. 3.3 %, P < 0.05). CONCLUSION: Preoperative aspirin therapy does not seem to influence the operative outcome of isolated CABG. Therefore, the often given recommendation to stop this therapy prior to elective CABG procedures should be abandoned.


Subject(s)
Aspirin/administration & dosage , Coronary Artery Bypass/adverse effects , Platelet Aggregation Inhibitors/administration & dosage , Postoperative Hemorrhage/prevention & control , Aged , Aspirin/adverse effects , Coronary Artery Bypass, Off-Pump/adverse effects , Drug Administration Schedule , Female , Humans , Male , Middle Aged , Platelet Aggregation Inhibitors/adverse effects , Postoperative Hemorrhage/etiology , Practice Guidelines as Topic , Preoperative Care , Reoperation , Retrospective Studies , Risk Assessment , Time Factors , Treatment Outcome
14.
J Plast Reconstr Aesthet Surg ; 62(11): 1479-83, 2009 Nov.
Article in English | MEDLINE | ID: mdl-18996074

ABSTRACT

In cardiac surgery poststernotomy mediastinitis continues to be a serious cause of morbidity and mortality. We report our experience with vacuum-assisted closure (VAC) therapy followed by reconstruction with M. pectoralis muscle flaps as treatment for deep sternal wound infections. Our group performed a retrospective analysis of 3630 consecutive cardiac surgical patients using median sternotomy from 11/2004 to 11/2007. After removing sternal wires, necrotic debris and potentially infective material, restabilisation of the sternum was performed and VAC therapy was employed. Wound closure and subsequent reconstruction were performed using a bilateral pectoralis muscle plasty. Of the analysed patients 16 female and 29 male patients suffered from deep sternal wound infections and were treated with VAC. The most common risk factors were diabetes mellitus odds ratio (OR 3.5), chronic obstructive pulmonary disease (COPD) (OR 2.9), use of bilateral mammarian artery (OR 2.0) and obesity (1.8). The median age of patients with deep sternal infections was similar to control patients. Staphylococcus epidermis was the most common pathogen (37.8%) followed by Enterococcus faecilis (22.2%) and Staphylococcus aureus (17.8). In 22.2% no pathogen could be detected. The 30 day mortality was 0%, the in-hospital mortality was 15.6%. The results of our studies demonstrate that vacuum therapy in conjunction with early and aggressive debridement is an effective strategy for treating poststernotomy mediastinitis. We consider pectoralis major muscle flap reconstruction as a safe technique and regard it as the primary choice for wound closure in poststernotomy mediastinitis.


Subject(s)
Mediastinitis/surgery , Negative-Pressure Wound Therapy/methods , Plastic Surgery Procedures/methods , Sternotomy/adverse effects , Surgical Flaps/blood supply , Surgical Wound Infection/surgery , Aged , Chi-Square Distribution , Cohort Studies , Debridement/methods , Female , Follow-Up Studies , Humans , Male , Mediastinitis/etiology , Middle Aged , Multivariate Analysis , Pectoralis Muscles/blood supply , Pectoralis Muscles/transplantation , Probability , ROC Curve , Retrospective Studies , Risk Assessment , Sternotomy/methods , Surgical Wound Infection/diagnosis , Survival Rate , Thoracic Surgical Procedures/adverse effects , Thoracic Surgical Procedures/methods , Treatment Outcome , Wound Healing/physiology
15.
Dtsch Med Wochenschr ; 133(46): 2393-402; quiz 2403-6, 2008 Nov.
Article in German | MEDLINE | ID: mdl-18988132

ABSTRACT

Caused by the age-dependent prevalence of cardiac diseases, the number of cardiac surgical interventions to geriatric patients is increasing. High life quality and life expectancy can be reached by cardiac operations. The advantage of cardiac surgical interventions is the decade's long positive effect. Accordingly also elderly benefit from complete revascularisation and from aortic valve replacement with biological prosthesis, which rarely degenerate in old age. A weak point is the surgical trauma, which can be reduced by less-invasive methods, such as OPCAB with aortic non-touch-technique, resulting in less than 1 % stroke. The indications for heart operations will be based on age-independent evidence-based guidelines. The decision for surgery is influenced by the expectation of the risk. This is defined by the co-morbidities and to lesser extent by the age per se. The operation risk can be calculated by risk-scores and hospital-specific data. The patient's expectations from the operation and his ability to overcome the accompanying stress must be thoroughly assessed. The operation must take place electively and at the right time. A good nutritional status and preoperative optimization of the organ functions are decisive for the prognosis. The blood-sugar-level must be optimized; thyroid function, (hidden) infections, anaemia and depression must be excluded or treated. The required screening tests should have been done already by the family doctor. The elderly are postoperatively susceptible to complications; especially low cardiac output, renal failure, respiratory insufficiency and stroke. Subsequently they need more intensive care.


Subject(s)
Aortic Valve Stenosis/surgery , Cardiac Surgical Procedures/methods , Cardiac Surgical Procedures/standards , Perioperative Care/standards , Aged , Aged, 80 and over , Aortic Valve Stenosis/diagnosis , Cardiac Surgical Procedures/psychology , Heart Valve Prosthesis Implantation/methods , Heart Valve Prosthesis Implantation/standards , Humans , Male , Perioperative Care/methods , Postoperative Complications/etiology , Postoperative Complications/therapy , Risk Factors
16.
Thorac Cardiovasc Surg ; 56(8): 461-6, 2008 Dec.
Article in English | MEDLINE | ID: mdl-19012210

ABSTRACT

BACKGROUND: When composite arterial T-grafts are used, uncertainty persists as to whether the RIMA will be long enough to reach the RCA. We present a formula for the preoperative estimation of the required conduit length. METHODS: The following formula was created to estimate the required conduit length for a sequential graft, starting from the proximal RIMA-LIMA T-graft anastomosis, passing the PLA, and ending at the PDA: 2.14 x ([2 x LV wall thickness [WT]) + end-diastolic diameter (EDD)]. The estimated length was compared to the measured length in 100 patients undergoing off-pump revascularisation with BIMA T-grafts. RESULTS: There were no hospital deaths, no major infarctions and no wound complications. The required conduit length varied from 11.5 cm to 19 cm (average 14.9 +/- 1.4 cm) and was excellently predicted by the formula (paired T-test: P < 0.001, r = 0.86, average overestimation: 0.55 cm). CONCLUSION: The formula reliably determines the minimum required conduit length. We recommend this formula for preoperative decision making when considering the choice of graft and the length of RIMA harvesting. To facilitate calculation a simplified version is useful: 2 x EDD + 4 x WD + 1. Avoiding uncertainty about the sufficiency of the RIMA length may contribute to the spread of this technique.


Subject(s)
Internal Mammary-Coronary Artery Anastomosis/methods , Aged , Coronary Artery Bypass, Off-Pump , Female , Humans , Male , Mammary Arteries/surgery
17.
Clin Res Cardiol ; 97(3): 176-80, 2008 Mar.
Article in English | MEDLINE | ID: mdl-18193375

ABSTRACT

INTRODUCTION: The number of patients with an indication for cardiac surgery in their ninth decade of life is increasing. This study analyses the single-center results with combined and redo cardiac surgical procedures in octogenarians retrospectively. PATIENTS AND METHODS: Three groups were evaluated: (I) Two hundred and thirty six patients with combined cardiac surgical procedures, mean age 83.1 +/- 2.5 years, 107 male (129 female). Combined aortic valve replacement (AVR) and aorto coronary bypass (ACB) was done in 215, double valve replacement (DVR) in 21. (II) AVR + ACB-group: 215 patients out of group I. (III) Control group consisting of 124 patients with a mean age of 74.1 +/- 2.8 years (range 70-79.9 years) who received combined AVR and ACB. Risk stratification was done using the additive and logistic Euro-score; values are given as mean +/- standard deviation and were compared using either the t-test or the Chi-square test. RESULTS: The observed mortality in group I was 9.3%. Re-intubation was observed in 10.2% and was one major risk factor for in-hospital mortality. As second risk factor, DVR could be identified. 14.8% required hemodialysis postoperatively, but this affected only the length of stay on intensive care unit (ICU) but not mortality. When comparing group II with group III, mortality was higher (10% vs. 4%), the need for hemodialysis was more frequent (16.3% vs. 4.9%), and the incidence of postoperative psycho-syndromes was also higher (26% vs. 8.1%, all: P < 0.05). The duration of ventilation (2.7 +/- 7.7 vs. 1.6 +/- 4.3 days) and the length of stay on ICU (8.2 +/- 8.8 vs. 5.7 +/- 6.4) were longer without reaching statistical significance (P > 0.05). The Euro-score overestimated the real mortality in all groups. CONCLUSIONS: Octogenarians requiring combined cardiac surgical procedures required more resources and had a higher in-hospital mortality compared to younger patients. The observed in-hospital mortality was much lower than the predicted justifying the indication for surgical therapy in these patients. Patient selection, however, seems to be important but the Euro-score alone was rather ineffective in predicting poor outcome.


Subject(s)
Aged, 80 and over , Cardiac Surgical Procedures/methods , Aged , Aortic Valve/surgery , Cardiac Surgical Procedures/adverse effects , Cardiac Surgical Procedures/mortality , Coronary Artery Bypass , Female , Hospital Mortality , Humans , Length of Stay , Longitudinal Studies , Male , Patient Selection , Postoperative Complications , Respiration, Artificial , Retrospective Studies , Risk Assessment , Risk Factors , Treatment Outcome
18.
Thorac Cardiovasc Surg ; 55(8): 494-9, 2007 Dec.
Article in English | MEDLINE | ID: mdl-18027335

ABSTRACT

INTRODUCTION: The operative results of cardiac surgical procedures performed either by staff surgeons or trainees were compared to evaluate whether there is any additional risk to the patient in operations carried out by trainees. PATIENT AND METHODS: Between 1994 and 2006, 13 197 operations were done by 9 staff surgeons (S-group) and were compared to 1925 operations performed by 10 residents during their training program (R-group). In both groups, subgroups were defined in which patients either underwent isolated coronary artery bypass grafting (CABG) or aortic valve replacement (AVR). Isolated CABG was performed in 8725 cases (S-group) and 1706 cases (R-group). AVR was done in 1273 patients (S-group) and 191 patients in the R-group. The groups were compared with regard to length of surgery, in-hospital mortality, reexploration for bleeding, sternal wound complications, preoperative infarction and stroke. For overall risk stratification, the EuroSCORE was used. In the CABG groups, the KCH score was additionally used. RESULTS: Overall mortality was 0.5 % in the R-group (predicted mortality: 4.6 +/- 5 %) compared to 2 % in the S-group (predicted mortality: 6.9 +/- 7.9 %). Analyzing the CABG groups, mortality was 0.7 % in the R-group (predicted: 1.9 +/- 1.8 %) compared to 1.3 % in the S-group (predicted: 2.1 +/- 2.3 %). The rate of reexplorations for bleeding was 1 % in the R-group compared to 2 % in the S-group ( P < 0.05). Duration of extracorporeal circulation (ECC) was slightly longer in the R-group (95.8 +/- 33 compared to 85.5 +/- 28.3 minutes) without reaching statistical significance ( P > 0.05). Analyzing the AVR group, there was a 0.6 % mortality in the R-group (predicted: 6.5 +/- 6 %) compared to 3.1 % in the S-group (predicted: 8.8 +/- 8 %). Again, there were significantly more reexplorations for bleeding in the S-group (0.6 % vs. 2.8 %, P < 0.05). Time on ECC was longer in the R-group (101.6 +/- 21.6 vs. 96.6 +/- 35 minutes) with a resulting longer cross-clamping time (71.2 +/- 17.1 vs. 63.5 +/- 21 minutes). CONCLUSIONS: Training in cardiac surgery can be done with excellent results and no additional risk to the patients. Both groups performed similarly and had outcomes better than the predicted mortality. Training was mostly performed with isolated coronary artery bypass grafting procedures, resulting in only a small surgical spectrum at the time of board certification.


Subject(s)
Cardiac Surgical Procedures/education , Cardiac Surgical Procedures/standards , Cardiology/education , Education, Medical, Continuing/trends , General Surgery/education , Heart Diseases/surgery , Program Evaluation/standards , Aged , Female , Follow-Up Studies , Humans , Male , Program Evaluation/trends , Retrospective Studies , Time Factors , Treatment Outcome
19.
Versicherungsmedizin ; 59(3): 123-8, 2007 Sep 01.
Article in German | MEDLINE | ID: mdl-17912886

ABSTRACT

BACKGROUND: Lengthy recovery and treatment times following cardiosurgical interventions were the motivation for introducing a pilot procedure to integrate acute and rehabilitative treatment structures. The advantage of such a pilot procedure is the medico-economic link between direct transition from acute care to rehabilitation treatment and cutting average case costs. With this in mind, shared case fees for patients following cardiosurgery are being agreed in a pilot project between health insurance companies, acute-care hospitals and rehabilitation clinics. The aim of this study was thus to investigate whether rehabilitation directly after cardiosurgery without prior transferral to an acute-care hospital is comparable with the conventional procedure involving acute care. METHODS: A total of 221 patients were included in the investigation. The pilot project group comprised 159 patients (mean age 70 +/- 6 yrs, 117 men and 42 women) who were transferred directly to rehabilitation following cardiosurgery. The control group, comprising 62 patients (mean age = 71 +/- 6 yrs, 42 men and 20 women), was transferred to an acute-care hospital following cardiosurgery before commencing rehabilitation. Sociodemographic and clinical data were comparable between the two groups. RESULTS: At the end of rehabilitation, the mean maximum ergometric performance in the pilot group was 96 +/- 33 W, significantly higher than the control group's performance of 81 +/- 31 W. One difference between the two groups related to complications. During rehabilitation, complications occurred more frequently within the pilot group. In the pilot group, compared to the control group, postcardiotomy syndrome occurred in 45.3 versus 25.8% and impaired wound healing in 10.1 versus 4.8% of cases. Despite these results, the pilot group demonstrated a significantly shorter overall hospital stay of 39.5 +/- 7.5 days compared to the control group stay of 45.7 +/- 9.7 days. CONCLUSION: Compared to the control group, the pilot group was at no disadvantage with regard to clinical or performance data by the end of rehabilitation. Cardiac complications occur more often during rehabilitation taking place directly after cardiosurgery than with the conventional procedure. These can be viewed, however, as complications occurring directly in temporal conjunction with the operation and as to be expected. Complications attributed directly to fast-track rehabilitation can be excluded. In the pilot group the overall hospital stay was thus shortened. In an environment of legislative restructuring within the healthcare sector, this shows that adequate treatment of cardiosurgical patients is still guaranteed with fast-track rehabilitation.


Subject(s)
Cardiovascular Surgical Procedures/economics , Cardiovascular Surgical Procedures/rehabilitation , Delivery of Health Care, Integrated/economics , Fee-for-Service Plans/organization & administration , Fee-for-Service Plans/statistics & numerical data , Rehabilitation/economics , Rehabilitation/statistics & numerical data , Aged , Capitation Fee/legislation & jurisprudence , Cardiovascular Surgical Procedures/statistics & numerical data , Delivery of Health Care, Integrated/methods , Delivery of Health Care, Integrated/statistics & numerical data , Germany , Humans , Male , Pilot Projects , Recovery of Function , Treatment Outcome
20.
Cardiovasc J S Afr ; 17(5): 257-8, 2006.
Article in English | MEDLINE | ID: mdl-17117232

ABSTRACT

Dextrocardia associated with situs inversus totalis is a rare condition and there are few reports of myocardial revascularisation in such patients. An 82-year-old woman with dextrocardia and situs inversus totalis underwent successful off-pump coronary artery bypass grafting using internal mammary arteries. The operative technique was similar to that of off-pump coronary artery bypass grafting for situs solitus. However, for a right-handed surgeon the operation was easier standing on the left side of the patient.


Subject(s)
Coronary Artery Bypass, Off-Pump , Coronary Stenosis/surgery , Dextrocardia/surgery , Situs Inversus/surgery , Aged, 80 and over , Coronary Stenosis/diagnostic imaging , Coronary Stenosis/etiology , Dextrocardia/complications , Dextrocardia/diagnostic imaging , Female , Humans , Radiography , Situs Inversus/complications , Situs Inversus/diagnostic imaging
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