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Arch Oral Biol ; 54(10): 970-5, 2009 Oct.
Article in English | MEDLINE | ID: mdl-19698936

ABSTRACT

OBJECTIVE: To find out whether the stimulated saliva flow rate (SSFR) is a variable and unpredictable characteristic as healthy children grow-up. DESIGN: Seven-year-old school children (53 boys and 57 girls) were recruited to measure their SSFR in mL/min. Paraffin-stimulated saliva was collected from each child at baseline and once annually, over six years. Forty-four boys and 46 girls remained in the cohort (dropout rate 18%). Cluster analysis was applied to evaluate the natural grouping of individuals according to their SSFR. Partition analysis was applied to calculate the SSFR cut-off value to predict a child's salivation trend. RESULTS: Cluster analysis revealed that as they grew-up these children consistently showed one of three different SSFR patterns. The cut-off values to predict a child's salivation trend were 1.76 mL/min for the high SSFR cluster, and 0.5 mL/min for the low SSFR cluster. CONCLUSIONS: These findings indicate that a high or low SSFR is a constant individual trait in children.


Subject(s)
Saliva/metabolism , Salivation/physiology , Child , Cluster Analysis , Female , Humans , Logistic Models , Longitudinal Studies , Male , Reference Values , Secretory Rate , Stimulation, Chemical
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