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Health Phys ; 104(4): 366-78, 2013 Apr.
Article in English | MEDLINE | ID: mdl-23439140

ABSTRACT

A new modification of the prior human lung compartment plutonium model, Doses-2005, has been described. The modified model was named "Mayak Worker Dosimetry System-2008" (MWDS-2008). In contrast to earlier models developed for workers at the Mayak Production Association (Mayak PA), the new model more correctly describes plutonium biokinetics and metabolism in pulmonary lymph nodes. The MWDS-2008 also provides two sets of doses estimates: one based on bioassay data and the other based on autopsy data, where available. The algorithm of internal dose calculation from autopsy data will be described in a separate paper. Results of comparative analyses of Doses-2005 and MWDS-2008 are provided. Perspectives on the further development of plutonium dosimetry are discussed.


Subject(s)
Lung/metabolism , Lymph Nodes/metabolism , Models, Biological , Occupational Exposure/adverse effects , Plutonium/urine , Power Plants , Radiation Monitoring , Autopsy , Biological Assay , Female , Humans , Lung/radiation effects , Lymph Nodes/radiation effects , Male , Plutonium/pharmacokinetics , Tissue Distribution
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