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1.
Circulation ; 134(21): 1655-1663, 2016 Nov 22.
Article in English | MEDLINE | ID: mdl-27754882

ABSTRACT

BACKGROUND: Because of its low prevalence, data on atypical atrioventricular nodal reentrant tachycardia (AVNRT) are scarce, and the optimal ablation method has not been established. Our study aimed at assessing the efficacy and safety of conventional slow pathway ablation, as applied for typical cases, in atypical AVNRT. METHODS: We studied 2079 patients with AVNRT subjected to slow pathway ablation. In 113 patients, mean age 48.5±18.1 years, 68 female, atypical AVNRT or coexistent atypical and typical AVNRT without other concomitant arrhythmia was diagnosed. Ablation data and outcomes were compared with a group of age- and sex-matched control patients with typical AVNRT. RESULTS: Fluoroscopy and radiofrequency current delivery times were not different in the atypical and typical groups, 20.3±12.2 versus 20.8±12.9 minutes (P=0.730) and 5.9±5.0 versus 5.5±4.5 minutes (P=0.650), respectively. Slow pathway ablation was accomplished from the right septum in 110 patients, and from the left septum in 3 patients, in the atypical group. There was no need for additional ablation lesions at other anatomic sites, and no cases of atrioventricular block were encountered. Recurrence rates of the arrhythmia were 5.6% in the atypical (6/108 patients) and 1.8% in the typical (2/111 patients) groups in the next 3 months following ablation (P=0.167). CONCLUSIONS: Conventional ablation at the anatomic area of the slow pathway is the therapy of choice for symptomatic AVNRT, regardless of whether the typical or atypical form is present.


Subject(s)
Catheter Ablation/methods , Electrocardiography/methods , Tachycardia, Atrioventricular Nodal Reentry/physiopathology , Female , Humans , Male , Middle Aged
2.
Circ Arrhythm Electrophysiol ; 4(4): 486-93, 2011 Aug.
Article in English | MEDLINE | ID: mdl-21562203

ABSTRACT

BACKGROUND: A left bundle-branch block (LBBB)-like pattern with a dominant S-wave in V(1) is common in idiopathic ventricular arrhythmias (VA). Discrimination between idiopathic and scar-related LBBB pattern VA has important clinical implications. We hypothesized that the VA QRS morphology is influenced by the presence of ventricular scar, allowing ECG discrimination of VA arising from structurally normal versus scarred myocardium. METHODS AND RESULTS: Twelve-lead ECGs of 297 LBBB pattern monomorphic VA were recorded during catheter ablation procedures. QRS morphology characteristics associated with scar-related VA were identified in retrospective analysis of 118 LBBB pattern VA (95 scar-related, 23 idiopathic) to develop a stepwise algorithm that was prospectively tested in 179 LBBB pattern VA (120 scar-related, 59 idiopathic). The diagnosis of scar was based on sinus rhythm surface ECG, cardiovascular imaging, and electroanatomic catheter mapping. A precordial transition beyond V4, notching of the S-wave downstroke in lead V1 or V2, and a duration from the onset of QRS to the S-nadir in V1 >90 ms were independent predictors for scar-related VA. The proposed algorithm classified a VA as scar-related if any of these criteria was met. If none of the criteria was present, a VA was classified as idiopathic. In prospective validation, the algorithm was highly sensitive (96%) and specific (83%) for the identification of scar-related LBBB pattern VA. CONCLUSIONS: The QRS morphology of VA is different between scar-related and idiopathic VA. A simple ECG algorithm is sensitive for identifying scar-related LBBB VA, which could be helpful in guiding further evaluation of these patients.


Subject(s)
Bundle-Branch Block/diagnosis , Bundle-Branch Block/physiopathology , Cicatrix/complications , Cicatrix/diagnosis , Electrocardiography , Tachycardia, Ventricular/etiology , Tachycardia, Ventricular/physiopathology , Adult , Aged , Algorithms , Bundle-Branch Block/epidemiology , Catheter Ablation , Comorbidity , Diagnosis, Differential , Electrocardiography/methods , Electrophysiologic Techniques, Cardiac , Female , Humans , Logistic Models , Male , Middle Aged , Prospective Studies , Retrospective Studies , Sensitivity and Specificity , Tachycardia, Ventricular/epidemiology
3.
Pacing Clin Electrophysiol ; 31(1): 131-4, 2008 Jan.
Article in English | MEDLINE | ID: mdl-18181924

ABSTRACT

A case of successful laser extraction of a defibrillator lead with baffle stenting in a 15-year-old boy with dextrocardia, L-transposition, ventricular septal defect, and pulmonic stenosis status-post Senning/Rastelli repair is presented. Six-month follow-up revealed a significant increase in exercise tolerance and maximum oxygen consumption (VO(2)max).


Subject(s)
Defibrillators, Implantable , Lasers , Stents , Tachycardia, Ventricular/therapy , Transposition of Great Vessels/therapy , Adolescent , Coronary Angiography , Device Removal/methods , Humans , Male , Retreatment , Transposition of Great Vessels/surgery
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