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Psychiatry Res ; 58(3): 247-57, 1995 Oct 16.
Article in English | MEDLINE | ID: mdl-8570780

ABSTRACT

Quantitative electroencephalographic (QEEG) analyses are presented for a group of 90 subjects recovering from polysubstance abuse (median = 90 days abstinent) who preferentially used cocaine. QEEGs showed significant decreases from normal in both absolute and relative delta power and decreased theta power in both absolute and relative power. Significantly increased relative but not absolute alpha and beta power was found. Asymmetry of frontal delta, theta, and alpha power differed from normal with right power greater than left. Globally, reduced interhemispheric coherence was found in delta and theta bands and frontally in the beta band. An atypical EEG pattern was observed in about half of the subjects. This was a paroxysmal-like EEG alpha pattern reminiscent of vertex waves typically associated with drowsiness but lacking the waxing and waning of alpha and the slow lateral eye drift associated with drowsiness.


Subject(s)
Cocaine/adverse effects , Electroencephalography/drug effects , Illicit Drugs/adverse effects , Psychotropic Drugs/adverse effects , Substance Withdrawal Syndrome/physiopathology , Substance-Related Disorders/physiopathology , Adult , Alcoholism/physiopathology , Alcoholism/rehabilitation , Brain Mapping , Cerebral Cortex/drug effects , Cerebral Cortex/physiology , Female , Humans , Male , Marijuana Abuse/physiopathology , Marijuana Abuse/rehabilitation , Middle Aged , Signal Processing, Computer-Assisted , Substance Withdrawal Syndrome/rehabilitation , Substance-Related Disorders/rehabilitation
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