ABSTRACT
In 2012, an unprecedented number of four distinct, partially overlapping filovirus-associated viral hemorrhagic fever outbreaks were detected in equatorial Africa. Analysis of complete virus genome sequences confirmed the reemergence of Sudan virus and Marburg virus in Uganda, and the first emergence of Bundibugyo virus in the Democratic Republic of the Congo.
Subject(s)
Disease Outbreaks , Filoviridae Infections/epidemiology , Filoviridae/genetics , Filoviridae/isolation & purification , Genome, Viral , Hemorrhagic Fevers, Viral/epidemiology , RNA, Viral/genetics , Democratic Republic of the Congo/epidemiology , Filoviridae/classification , Filoviridae Infections/virology , Hemorrhagic Fevers, Viral/virology , Humans , Molecular Sequence Data , Sequence Analysis, DNA , Uganda/epidemiologyABSTRACT
Surveillance work was initiated to study the presence of highly infectious diseases like Ebola-Reston, Marburg, Nipah and other possible viruses that are known to be found in the bat species and responsible for causing diseases in humans. A novel adenovirus was isolated from a common species of fruit bat (Rousettus leschenaultii) captured in Maharashtra State, India. Partial sequence analysis of the DNA polymerase gene shows this isolate to be a newly recognized member of the genus Mastadenovirus (family Adenoviridae), approximately 20% divergent at the nucleotide level from Japanese BatAdV, its closest known relative.
