ABSTRACT
Prevention, early detection, morbidity, and survival issues continue to challenge health professionals involved in the care of women with ovarian cancer. While advances in diagnosis, staging, and treatment have been made, survival rates remain grim. Continuing research in the areas of screening, diagnosis, and treatment is the key to improved survival. The hope of new drug therapy, such as cisplatin-taxol regimens, intraperitoneal therapy, immunotherapy, and bone marrow transplantation, needs further investigation to become reality. As new and potentially more toxic regimens are developed, the nurse must be knowledgeable about the therapies and adverse effects, and maintain a high level of clinical expertise in order to teach the patient, reinforce information, clarify misconceptions, and provide the patient with supportive physical and emotional care.
Subject(s)
Carcinoma/therapy , Ovarian Neoplasms/therapy , Carcinoma/classification , Carcinoma/pathology , Combined Modality Therapy/methods , Female , Humans , Laparotomy , Neoplasm Staging , Neoplasms, Germ Cell and Embryonal/classification , Neoplasms, Germ Cell and Embryonal/therapy , Nursing Care , Ovarian Neoplasms/classification , Ovarian Neoplasms/pathologySubject(s)
Ascorbic Acid/adverse effects , Tooth Erosion/etiology , Adult , Ascorbic Acid/administration & dosage , Humans , Male , TabletsABSTRACT
Temperature rise on the surface of extracted human premolar roots was recorded during root canal preparation using a thermo-couple. It was found that time, pressure exerted on the reamer, type of reamer and rotational speed influenced the temperature rise. Starting from about 30 degrees C temperatures up to 87 degrees C were recorded, generally in less than 50 seconds' working time, using routine instrument and technique. Possible effects of this temperature rise on tooth substance, periodontal membrane and supporting bone are discussed.
Subject(s)
Periodontium/injuries , Root Canal Therapy/adverse effects , Temperature , Tooth Injuries , Dental Instruments , Humans , In Vitro Techniques , Pressure , Root Canal Therapy/instrumentation , Root Canal Therapy/methods , Time Factors , Tooth Root/injuriesABSTRACT
Two doublebling placebo controlled experiments designed to elucidate the alleged narcotic blocking effect of propranolol wer performed. In the first experiment, propranolol 40 mg or 20 mg was given together with methadone during the acute withdrawal phase of opiate addiction. The second experiment assessed whether 10 mg of propranolol, given 2 hrs before 30 mg of morphine i.v., reduced the euphoric effects of the latter drug. In none of the experiments could narcotic blocking effects be detected. The group receiving 40 mg propranolol during detoxification exhibited the highest proportion of patients staying for the whole prescribed detoxification period.
