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1.
Can J Ophthalmol ; 47(2): 107-12, 2012 Apr.
Article in English | MEDLINE | ID: mdl-22560413

ABSTRACT

OBJECTIVE: To investigate the effectiveness of information transfer by the pediatric cataract surgeon to the parents or guardians of children during the informed-consent process. DESIGN: Prospective observational case series. PARTICIPANTS: Parents of 31 children undergoing cataract surgery. METHODS: Parents were enrolled from the clinical practice of 1 pediatric cataract surgeon. Using a checklist developed in consultation with other pediatric cataract surgeons, the surgeon discussed the nature of the disease, the course without surgical intervention, the surgical procedure, the risks and benefits, and the postoperative care. Immediately after the discussion, parents were invited to complete a questionnaire assessing information recall. Analysis of variance and the t test were used to determine associations between questionnaire scores and demographic variables. The surgeon subsequently called parents and discussed again the issues that they had not remembered correctly, as identified by the questionnaire responses. The study and data accumulation were carried out with the approval of the Research Ethics Board at The Hospital for Sick Children, Toronto, Ont. Informed consent for the research was obtained from the parents or legal guardians of the children enrolled in the study. The study adhered to the tenets of the Declaration of Helsinki. RESULTS: Of 31 parents, 18 (58%) overestimated their understanding of the informed-consent discussion. Parents scored well on questions about the nature of the disease and the postoperative follow-up but scored lower on questions regarding surgical risks and outcomes. Parents identified several barriers to understanding, including the large amount of information, stress, and preoccupation with the child. No association was noted between the level of understanding and demographic factors. CONCLUSIONS: Parents may overestimate their understanding of informed-consent discussions. Some parents may be overly optimistic about risks and outcomes. The surgeon's follow-up communication with parents that addressed aspects insufficiently understood during the initial discussion provided a way of improving comprehension.


Subject(s)
Cataract Extraction , Comprehension , Informed Consent/legislation & jurisprudence , Legal Guardians , Parents , Pediatrics/legislation & jurisprudence , Adult , Child, Preschool , Communication , Health Knowledge, Attitudes, Practice , Humans , Lens Implantation, Intraocular , Professional-Family Relations , Prospective Studies , Risk Assessment , Surveys and Questionnaires
2.
Can J Ophthalmol ; 46(5): 425-7, 2011 Oct.
Article in English | MEDLINE | ID: mdl-21995986

ABSTRACT

OBJECTIVE: To evaluate macular and peripapillary retinal nerve fiber layer (RNFL) thickness in amblyopic eyes compared to the fellow eye. DESIGN: Cross-sectional study. PARTICIPANTS: 30 patients (60 eyes) older than 18 years of age with amblyopia. METHODS: Inclusion criteria included individuals older than 18 years, amblyopia, and best-corrected visual acuity (BCVA) ≤ 20/40. A complete medical history was taken and an eye examination carried out. Optical coherence tomography (OCT) was carried out on both eyes of all patients. Exclusion criteria included intraocular pressure (IOP) >23 mm Hg and eye pathology that may affect OCT measurements. The primary outcome measures were foveal thickness and average peripapillary RNFL thickness, which were compared using a paired t test. Quadrants in peripapillary scans and concentric rings in macular scans were analyzed. RESULTS: The average age was 56 years (range = 33-82 years). Visual acuity ranged from 20/40 to 20/4000 (mean = 20/275). The average peripapillary RNFL thickness was 90.6 µm (SD = 9.6 µm) in the amblyopic eye and 90.1 µm (SD = 12.1 µm) in the fellow eye (p = 0.64). The average macular thickness in amblyopic eyes was 260.1 µm (SD = 32.0 µm), and 254.7 µm (SD = 32.5 µm) in fellow eyes (p = 0.10). No statistical difference existed between peripapillary quadrants or macular concentric rings. These differences were smaller when the strabismic amblyopes were isolated. CONCLUSIONS: There does not seem to be a difference in peripapillary RNFL or macular thickness between the amblyopic eye and fellow eye.


Subject(s)
Amblyopia/diagnosis , Macula Lutea/pathology , Nerve Fibers/pathology , Optic Disk/pathology , Retinal Ganglion Cells/pathology , Adult , Aged , Aged, 80 and over , Cross-Sectional Studies , Humans , Middle Aged , Tomography, Optical Coherence , Visual Acuity/physiology
3.
J AAPOS ; 10(6): 528-33, 2006 Dec.
Article in English | MEDLINE | ID: mdl-17189146

ABSTRACT

PURPOSE: To ascertain the interobserver agreement among various specialists when analyzing images of the optic nerve head taken with the RetCam 120 (Clarity Medical Systems, Inc., Pleasanton, CA) for assessing the progression of optic disk cupping in pediatric glaucoma. METHODS: Five observers compared pairs of RetCam 120 two-dimensional photographs from 64 eyes to identify whether or not changes in the optic disk had occurred. Observers included a pediatric glaucoma specialist, pediatric neurophthalmologist, strabismologist, pediatric ophthalmic imaging specialist, and pediatric ophthalmology fellow. Each was masked to the patient identity and clinical course. For each patient, the observers reviewed the photographs taken prior to therapy and at a minimum of 6 months following initiation of therapy. Interobserver variability was calculated and analysis conducted to identify influential variables. RESULTS: Poor agreement was noted between the observers. No significant association was obtained between agreement level and variables affecting photographic quality: variability of contrast and illumination, exposure and magnification, image clarity, presence of fluorescein on the cornea, and pixelation of the image with poor resolution. Raters noted problems with these image variables in 75.6% of the observations. The Kappa statistic obtained was kappa = 0.29 with overall proportion of agreement of p = 0.69, suggesting a fair agreement but not a moderate agreement. CONCLUSIONS: Comparison of RetCam 120 pediatric optic nerve head photographs, when performed subjectively by observers with different perspectives, and in isolation from clinical information, may not be a reliable indicator of cupping change. In addition, variations in image contrast, luminance, color, and pixelation pose significant challenges to agreement between observers. Comparison of RetCam 120 images should not be considered the sole criterion for monitoring pediatric glaucoma.


Subject(s)
Diagnostic Techniques, Ophthalmological/instrumentation , Glaucoma/diagnosis , Optic Disk/pathology , Optic Nerve Diseases/diagnosis , Adolescent , Child , Child, Preschool , Follow-Up Studies , Glaucoma/pathology , Humans , Infant , Intraocular Pressure , Observer Variation , Optic Nerve Diseases/etiology , Photography/instrumentation , ROC Curve , Severity of Illness Index
4.
Invest Ophthalmol Vis Sci ; 46(11): 4107-13, 2005 Nov.
Article in English | MEDLINE | ID: mdl-16249487

ABSTRACT

PURPOSE: To examine the association between metabolic control (HbA(1c)) and the chromatic mechanisms of children with type 1 diabetes (T1D), by using the color visual evoked potential (VEP). METHODS: Fifty children with T1D (age range, 6-12.9 years) and 33 age-matched control subjects were tested. VEPs were recorded by placing five electrodes on the scalp according to the International 10/20 System of Electrode Placement. Active electrodes O1, O2, and Oz were placed over the visual cortex. Short-wavelength (S), and long- and medium-wavelength (LM) color stimuli consisted of vertical, photometric isoluminant (1 cyc/deg) gratings presented in a pattern onset (100 ms)-offset (400 ms) mode. Achromatic vertical gratings were presented at 3 cyc/deg. Primary outcome measure was VEP latency. The relationship between S, LM, and achromatic VEP latency, and HbA(1c) was determined by ANCOVA regression. RESULTS: S-, LM-, achromatic VEP latencies were not associated significantly with HbA(1c). Pubertal status, however, was associated significantly (P = 0.0114) and selectively with S-VEP latency. Pubertal children with T1D had delayed (mean delay, 9.5 ms) S-VEP latencies when compared with the prepubertal children with T1D. However, there was no statistically significant difference (P = 0.1573) in the effect of pubertal status on S-VEP latency between the T1D and control groups. CONCLUSIONS: Pubertal status rather than HbA(1c) appears to affect selectively the S-VEP latency of preteen children with T1D. Further study is warranted to determine whether the delay in S-VEP latency in pubertal children with T1D changes over time and whether this change could be a predictive marker for future development of background diabetic retinopathy.


Subject(s)
Color Perception/physiology , Diabetes Mellitus, Type 1/metabolism , Evoked Potentials, Visual/physiology , Glycated Hemoglobin/metabolism , Blood Glucose/metabolism , Child , Female , Humans , Male , Puberty/physiology
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