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Eur J Med Chem ; 41(6): 773-8, 2006 Jun.
Article in English | MEDLINE | ID: mdl-16563569

ABSTRACT

3-Arylamino-2-phenylsulfinylnaphthoquinones, 2,3-diarylthio-naphthoquinones and 2-phenylsulfinyl-3-arylthio-1,4-dihydronaphtalenes are synthesized and tested against five fungi. The activities of these products were better than amphotericine B against all the strains except for Candida albicans.


Subject(s)
Antifungal Agents/chemical synthesis , Antifungal Agents/pharmacology , Fungi/drug effects , Naphthoquinones/chemical synthesis , Naphthoquinones/pharmacology , Drug Evaluation, Preclinical , Microbial Sensitivity Tests , Species Specificity
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