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1.
Clin Neurol Neurosurg ; 210: 107011, 2021 11.
Article in English | MEDLINE | ID: mdl-34741975

ABSTRACT

Cerebral Proliferative Angiopathy (CPA) is a rare vascular malformation that is distinguished from classical brain arteriovenous malformations (AVM) in its imaging findings and clinical progression but more importantly in its pathophysiology. Here we report the case of a 37-year-old male patient with CPA accompanied by Cerebral Cavernous Malformation (CCM) in hopes to expand the inquiry into the pathophysiology of this rare lesion. A patient with progressive headache, right-sided weakness, and impaired speech were evaluated at our medical center. Neuroimaging studies were performed, and the patient was diagnosed with CPA. The patient has been followed up with conservative management and periodic neuroradiological evaluation for 5 years. Digital subtraction angiography (DSA) showed a vascular malformation diffusely covering the left hemisphere that is consistent with CPA. In addition, 2 sequential CCMs were detected in the right hemisphere. Also, the patients' familial history included two brothers with CCMs. The coexistence of CPA with CCM and patients' familial history of CCM could suggest the possibility of a common pathophysiological element.


Subject(s)
Cerebral Small Vessel Diseases/complications , Cerebral Small Vessel Diseases/diagnostic imaging , Hemangioma, Cavernous, Central Nervous System/complications , Hemangioma, Cavernous, Central Nervous System/diagnostic imaging , Adult , Anticonvulsants/therapeutic use , Antipsychotic Agents/therapeutic use , Cerebral Small Vessel Diseases/drug therapy , Gabapentin/therapeutic use , Haloperidol/therapeutic use , Hemangioma, Cavernous, Central Nervous System/drug therapy , Humans , Male
2.
Infez Med ; 27(1): 85-92, 2019 Mar 01.
Article in English | MEDLINE | ID: mdl-30882385

ABSTRACT

Invasive aspergillosis is a severe infection that generally involves the lungs. Primary gastrointestinal aspergillosis is the least common form of invasive aspergillosis. A patient aged 65 years developed a febrile neutropenic episode following an autologous stem cell transplant for plasmacytoid variant diffuse large B-cell gastric non-Hodgkin's lymphoma. He had abdominal pain on the second day of the febrile neutropenic episode and ileus occurred on the sixth day. His general condition deteriorated despite broad spectrum antibiotics and caspofungin treatment, and intestinal perforation occurred on the nineteenth day of the febrile neutropenic episode. Pathological examination of the resected jejunum and ileum revealed mould hyphae compatible with aspergillus. The patient died due to massive gastrointestinal bleeding on the fifth post-operative day. Although a rare condition, primary gastrointestinal aspergillosis should be kept in mind while treating neutropenic patients with gastrointestinal symptoms.


Subject(s)
Aspergillosis/complications , Febrile Neutropenia/microbiology , Gastrointestinal Diseases/microbiology , Hematopoietic Stem Cell Transplantation , Invasive Fungal Infections/microbiology , Aged , Antineoplastic Combined Chemotherapy Protocols/adverse effects , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Aspergillosis/diagnostic imaging , Fatal Outcome , Gastrointestinal Diseases/diagnostic imaging , Humans , Ileus/etiology , Immunocompromised Host , Invasive Fungal Infections/diagnostic imaging , Lymphoma, Large B-Cell, Diffuse/therapy , Male , Stomach Neoplasms/therapy
3.
Euroasian J Hepatogastroenterol ; 7(2): 178-180, 2017.
Article in English | MEDLINE | ID: mdl-29201804

ABSTRACT

AIM: A case of asymptomatic aneurysm of spontaneous portosystemic venous fistula (SPVF) with the radiologic findings is described. BACKGROUND: Although advances and more widespread use of ultrasound (US) and computed tomog -raphy angiography (CTA) have enabled more detection of SPVF in the liver, it is a rare entity. CASE REPORT: A 49-year-old male was referred to our hospital's nephrology outpatient clinic due to hypertension. Abdominal sonography examination detected a well-defined cystic lesion adjacent to the middle hepatic vein in the liver. The lesion showed venous flow in the color Doppler US examination. Computed tomography angiography examination revealed an aneurysm of the fistula. CONCLUSION: Radiologists should be aware of this vascular anomaly and cyst-like lesions in the liver should be examined with color Doppler ultrasonography for possible vascularization, and be differentiated with CTA if necessary. CLINICAL SIGNIFICANCE: This condition is usually encountered incidentally and patients usually have no symptoms. However, severe complications, such as hepatopulmonary syndrome, liver tumors, encephalopathy, and heart failure can be seen.How to cite this article: Ulus S, Akan GE, Erol C. Aneurysm of Portosystemic Fistula: A Case Report and Review of Literature. Euroasian J Hepato-Gastroenterol 2017;7(2):178-180.

4.
Spine J ; 16(10): e671-e672, 2016 Oct.
Article in English | MEDLINE | ID: mdl-26968239
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