1.
Prostaglandins Med
; 5(4): 255-8, 1980 Oct.
Article
in English
| MEDLINE
| ID: mdl-7443871
ABSTRACT
The effects of PGE2 and F2 alpha have been studied on E-rosette forming activity of normal human peripheral blood lymphocytes. Addition of both PGs into the incubation medium caused a significant and concentration - dependent inhibition of E-rosette formation. The minimum effective concentration of both PGs was found to be 10(-9) M and complete inhibition was obtained when the concentration was increased to 10(-7) M. Possible mechanisms of the action of PGs on E-rosette formation are discussed.