1.
J Am Acad Dermatol
; 88(6): 1370-1372, 2023 06.
Article
in English
| MEDLINE
| ID: mdl-36739902
2.
Dermatol Online J
; 26(1)2020 Jan 15.
Article
in English
| MEDLINE
| ID: mdl-32155033
ABSTRACT
Toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) are life-threatening, cutaneous reactions often associated with culprit drugs. A growing body of knowledge has deepened our understanding of the pathophysiology and clarified mechanisms such as drug-specific cytotoxicity mediated by T-cells, genetic linkage with HLA and non-HLA genes, TCR restriction, and cytotoxicity mechanisms. Physicians should broadly consider the etiology of SJS/TEN in order to better understand treatment strategies as well as identify which patients may be at risk for developing this condition. Mechanisms for how radiotherapy and rare malignancies may contribute to the development of TEN and SJS have been proposed.
Subject(s)
Liposarcoma/radiotherapy , Radiotherapy/adverse effects , Stevens-Johnson Syndrome/etiology , Humans , Male , Middle Aged , Radiation Injuries , Skin/pathology , Stevens-Johnson Syndrome/pathology
3.
4.
Pediatr Dermatol
; 36(5): 711-712, 2019 Sep.
Article
in English
| MEDLINE
| ID: mdl-31529633
5.