ABSTRACT
Propósito: Evaluar la eficacia de la biopsia del ganglio centinela (BGC), sin utilizar colorante azul, en pacientes con melanoma cutáneo. Material y métodos: Estudio prospectivo llevado a cabo sobre 42 pacientes consecutivos con melanomas primarios en estadio I-II según la AJCC. La BGC ha sido realizada mediante la combinación de linfogammagrafía preoperatoria y localización intraoperatoria del GC usando exclusivamente un detector manual de rayos gamma. Resultados: Se extirparon un total de 43 melanomas primarios en 42 pacientes. De los 46 GC identificados mediante la gammagrafia preoperatoria se consiguieron encontrar 45 durante la intervención, alcanzando un éxito en la técnica del 97,8 por ciento . Entre las 36 regiones ganglionares con BGC negativa ha aparecido una recidiva local, la cual ha sido considerada como un probable falso negativo (2,7 por ciento). Conclusiones: 1 ) La BGC es útil en el estadiaje y como factor pronóstico del melanoma cutáneo. 2) La inyección de colorante azul perdesional podría llegar a ser innecesaria en la BGC si se obtienen buenos resultados con la linfogammagrafía + detector manual de rayos gamma (AU)
Subject(s)
Adult , Female , Male , Humans , Biopsy , Ganglia , Melanoma , Prospective StudiesABSTRACT
UNLABELLED: The aim of this study is to characterise benign from malignant breast lesions by using 99mTc-Tetrofosmin. MATERIALS: Fifteen female patients with suspected breast lesions and ten normal controls underwent breast scintigraphy with 99mTc-Tetrofosmin. All patients had conventional mammography. Breast imaging begun 20 minutes after i.v. injection of 740 MBq 99mTc-Tetrofosmin. Patients were imaged in supine and prone position. Results of the 15 patients with suspected breast lesions, 13 showed breast uptake, and 6 of them had suspicious lesions on mammography. Surgery confirmed 10 carcinomas and 3 benign lesions. Two patients demonstrated no abnormal accumulation or suspicious findings in mammography. None of the normal controls had breast uptake or mammographic abnormalities. Our study has a sensibility of 100% and 60%, and a specificity of 80% and 100% in scintigraphy and mammography respectively. CONCLUSION: Our findings suggest that 99m Tc-Tetrofosmin may play a role in evaluating breast masses and that can differentiate benign from malignant lesions.
Subject(s)
Breast Diseases/diagnostic imaging , Breast Neoplasms/diagnostic imaging , Organophosphorus Compounds , Organotechnetium Compounds , Adolescent , Adult , Aged , Breast Diseases/pathology , Breast Diseases/surgery , Breast Neoplasms/surgery , Carcinoma/diagnostic imaging , Carcinoma/surgery , Diagnosis, Differential , Female , Gamma Cameras , Humans , Mammography , Middle Aged , Radionuclide Imaging , Radiopharmaceuticals , Sensitivity and SpecificityABSTRACT
We report the case of a 57-year-old woman with celiac disease of long standing, who developed episodes of intestinal obstruction during two months. They were misdiagnosed as intestinal obstructions caused by adhesions. The barium meal and follow-through examination disclosed several jejunal stenoses. Therefore, the patient underwent early surgery where an intestinal resection was carried out. The histological examination showed the presence of benign ulcers at the stenoses. After surgery, the patient began to gain weight and her nutritional state improved remarkably.
