Subject(s)
AIDS-Related Opportunistic Infections/pathology , Bronchial Diseases/pathology , Fistula/pathology , Lymph Nodes/pathology , Mycobacterium bovis , Tuberculosis, Pulmonary/pathology , AIDS-Related Opportunistic Infections/diagnostic imaging , Adult , Antitubercular Agents/therapeutic use , Bronchial Diseases/diagnostic imaging , Fatal Outcome , Fistula/diagnostic imaging , Humans , Male , Mediastinum , Mycobacterium bovis/isolation & purification , Mycobacterium tuberculosis/isolation & purification , Rupture, Spontaneous , Tomography, X-Ray Computed , Tuberculosis, Pulmonary/diagnostic imagingABSTRACT
OBJECTIVE: To determine the accuracy of fine needle aspiration (FNA) and intraoperative frozen section examination (IFSE) on thyroid nodules. STUDY DESIGN: The study group consisted of 470 patients who underwent thyroidectomy. FNA was performed on 289 patients and IFSE on 326. The FNA and IFSE results were compared with the final histologic diagnosis obtained after examination of permanent sections. RESULTS: The overall FNA sensitivity was 65%, specificity 88% and positive predictive value 61%. The IFSE sensitivity was 50%, and the specificity and positive predictive value were 100%. When both procedures were used together, FNA identified 16 of 45 (36%) carcinomas as malignant and an additional 13 (29%) as follicular proliferative lesions; IFSE correctly identified only 23 of 45 (51%) carcinomas. CONCLUSION: FNA provides enough information for determining the extent of thyroid surgery when a diagnosis of cancer is made. However, IFSE should be considered a supplementary procedure when FNA is not positive for cancer.
Subject(s)
Biopsy, Needle , Frozen Sections , Thyroid Nodule/diagnosis , Cytological Techniques , Histological Techniques , Humans , Sensitivity and SpecificitySubject(s)
Giardiasis/diagnosis , Intestinal Diseases, Parasitic/diagnosis , Jejunal Diseases/diagnosis , Mesenteric Lymphadenitis/diagnosis , Adult , Diagnosis, Differential , Enteritis/complications , Enteritis/diagnosis , Female , Giardiasis/complications , Humans , Intestinal Diseases, Parasitic/complications , Jejunal Diseases/complications , Jejunum/pathology , Mesenteric Lymphadenitis/etiologySubject(s)
Leiomyoma/complications , Pleural Effusion/etiology , Uterine Neoplasms/complications , Female , Humans , Middle AgedABSTRACT
The case of a 50-year-old woman with a retroperitoneal paraganglioma and nephrotic syndrome is presented. After the tumor was removed deposits of amyloid material were observed in the paraganglioma, kidneys, and liver. There was no thrombosis of the renal vein. The clinical picture (fever and nephrotic syndrome) was similar to that of patients with amyloidosis associated with neoplasms. The nephrotic syndrome disappeared 8 months after the operation. The patient has not had fever or nephrotic manifestations over the past 4 years and is asymptomatic at the present time. We believe this to be the first reported case of paraganglioma associated with amyloidosis. Nor have we found any references to clinical and biological remission of the nephrotic syndrome following surgical removal of the concomitant neoplasm.
