ABSTRACT
In the original publication [...].
ABSTRACT
The paper presents a traceability framework founded upon a methodological approach specifically designed for the integration of the IOTA-based distributed ledger within the mining industry. This framework constitutes an initial stride towards the certification and labelling of sustainable material production. The efficacy of this methodology is subject to real-world evaluation within the framework of the European Commission funded project DIG_IT. Within the architectural framework, the integration of decentralized identifiers (DIDs) and the IOTA network are instrumental in effecting the encryption of data records, with associated hashes securely anchored on the explorer. Recorded environmental parameters, encompassing metrics such as pH level, turbidity, electrical conductivity, and emissions, serve as tangible evidence affirming their adherence to prevailing regulatory standards. The overarching system architecture encompasses a sophisticated Industrial Internet of Things platform (IIoTp), facilitating the seamless connection of data from a diverse array of sensors. End users, including governmental entities, mining managers, and the general public, stand to derive substantial benefits from tailored dashboards designed to facilitate the validation of data for emission compliance.
ABSTRACT
Primary care antimicrobial stewardship program (ASP) interventions can reduce the over-prescription of unnecessary antibiotics, but the impact on the reduction in bacterial resistance is less known, and there is a lack of available data. We implemented a prolonged educational counseling ASP in a large regional outpatient setting to assess its feasibility and effectiveness. Over a 5-year post-implementation period, which was compared to a pre-intervention period, a significant reduction in antibiotic prescriptions occurred, particularly those associated with greater harmful effects and resistance selection. There was also a decrease in methicillin-resistant Staphylococcus aureus (MRSA) strains and in their co-resistance to other antibiotics, particularly those with an ecological impact.
ABSTRACT
Antimicrobial stewardship programs (ASPs) are a central component in reducing the overprescription of unnecessary antibiotics, with multiple studies showing benefits in the reduction of bacterial resistance. Less commonly, ASPs have been performed in outpatient settings, but there is a lack of available data in these settings. We implemented an ASP in a large regional outpatient setting to assess its feasibility and effectiveness. Over a 5-year post-implementation period, compared to the pre-intervention period, a significant reduction in antibiotic prescription occurred, with a reduction in resistance in E. coli urinary isolates. ASP activities also were found to be cost-effective, with a reduction in medication prescription.
