ABSTRACT
BACKGROUND: Atrial fibrillation (AF) is one of the most common complications after coronary artery bypass grafting (CABG). This study was designed to evaluate whether the levels of preoperative and postoperative N-terminal pro-brain natriuretic peptide (NT-proBNP) are predictors of postoperative paroxysmal atrial fibrillation in patients who undergo coronary artery bypass surgery. METHODS: A total of 117 patients were prospectively evaluated for new-onset AF after coronary operation. Plasma NT-proBNP values in all patients were measured at five different time points. RESULTS: AF occurred during the hospitalization period in 33 patients (28.2 %). Significantly higher NT-proBNP levels in the preoperative examination were recorded in patients who developed AF postoperatively compared with patients without postoperative AF (329.36 ± 82.93 vs. 230.67 ± 59.93 pg/ml, P < 0.05). Although we detected some higher values in the other group of patients with AF (at T1, T2, T3, T4), the difference was not statistically significant compared to the normal rhythm group. CONCLUSION: The main finding of the current study is a positive correlation between high levels of preoperative NT-proBNP and the risk of new-onset AF after CABG surgery.
Subject(s)
Atrial Fibrillation/etiology , Coronary Artery Bypass/adverse effects , Coronary Artery Disease/surgery , Natriuretic Peptide, Brain/blood , Peptide Fragments/blood , Aged , Atrial Fibrillation/blood , Atrial Fibrillation/diagnosis , Biomarkers/blood , Coronary Artery Disease/blood , Electrocardiography , Female , Humans , Male , Middle Aged , Predictive Value of Tests , Preoperative Period , Prospective Studies , ROC Curve , Risk Assessment , Risk Factors , Time Factors , Treatment Outcome , Turkey , Up-RegulationABSTRACT
AIM: Chronic venous insufficiency and the development of venous ulceration, as a result of this condition affects quality of life. In order to avoid skin changes and allow for quick remedy, subfacial endoscopic perforator surgery (SEPS) has been suggested and gained some popularity. The purpose of this study was to assess the healing rate of venous ulcers in patients undergoing SEPS. METHODS: The SEPS procedure by using two ports was applied in 20 patients with active venous ulceration (CEAP-C6). The results were evaluated by Doppler findings, Venous Disability Score (VDS) and Venous Clinical Severity Score (VCSS) before and after the operation. Patients with prior deep vein thrombosis were excluded from this study. RESULTS: The ulcers healed in all patients. Significant clinical improvement according to VDS and VCSS values was obtained in all patients after the procedures. There was no mortality or any other major complication during the follow up period. CONCLUSION: The advantages of using two-port, video-controlled SEPS procedure may provide freedom from the skin complications that can be seen after Linton operation with quick and sustainable ulcer healing.
