ABSTRACT
The algorithm for the Dexcom G6 CGM System was enhanced to retain accuracy while reducing the frequency and duration of sensor error. The new algorithm was evaluated by post-processing raw signals collected from G6 pivotal trials (NCT02880267) and by assessing the difference in data availability after a limited, real-world launch. Accuracy was comparable with the new algorithm-the overall %20/20 was 91.7% before and 91.8% after the algorithm modification; MARD was unchanged. The mean data gap due to sensor error nearly halved and total time spent in sensor error decreased by 59%. A limited field launch showed similar results, with a 43% decrease in total time spent in sensor error. Increased data availability may improve patient experience and CGM data integration into insulin delivery systems.
Subject(s)
Blood Glucose Self-Monitoring , Diabetes Mellitus, Type 1 , Algorithms , Blood Glucose , Blood Glucose Self-Monitoring/methods , Diabetes Mellitus, Type 1/drug therapy , Humans , Insulin/therapeutic use , Insulin Infusion Systems , Reproducibility of ResultsABSTRACT
We improve the overall rate-distortion performance of distributed video coding by efficient techniques of correlation noise estimation and key frame encoding. In existing transform-domain Wyner-Ziv video coding methods, blocks within a frame are treated uniformly to estimate the correlation noise even though the success of generating side information is different for each block. We propose a method to estimate the correlation noise by differentiating blocks within a frame based on the accuracy of the side information. Simulation results show up to 2 dB improvement over conventional methods without increasing encoder complexity. Also, in traditional Wyner-Ziv video coding, the intercorrelation of key frames is not exploited since they are simply intracoded. In this paper, we propose a frequency band coding mode selection for key frames to exploit similarities between adjacent key frames at the decoder. Simulation results show significant improvement especially for low-motion and high frame rate sequences. Furthermore, the advantage of applying both schemes in a hierarchical order is investigated. This method achieves additional improvement.
