ABSTRACT
OBJECTIVES: To determine the prevalence of dementia and to measure the monetary impact and health resources utilization of vascular dementia (VD) compared to Alzheimer's dementia (AD) in persons aged over 64 years in a population setting. METHODS: Retrospective, cross-sectional study. In the initial phase, information was obtained on specific clinical characteristics from the subjects with an active diagnosis of dementia. The second phase consisted of a clinical evaluation and validation of the cases. Mini-Mental State Examination was used to assess cognitive impairment. Dementia and its subtypes were determined using established diagnostic criteria. Information was obtained on the use of health care resources (direct costs) and the number of hours devoted by the primary caregiver (indirect costs) for patients with a documented diagnosis of AD or VD within the last 6 months prior to the interview. A multiple logistic regression analysis was performed to correct the model. RESULTS: A total of 6,004 subjects were analyzed, 258 with diagnosis of dementia (overall prevalence: 4.3%). An evaluation was made of 224 patients, and gross prevalence of AD and VD was 2.4 and 1.0%, respectively. Cost per patient per semester was EUR 8,086 for AD and EUR 11,039 for VD (p = 0.016). 85.5% of the cost was attributable to primary caregiver time in AD and 84.4% in VD. CONCLUSIONS: The prevalence of AD and VD increases with age. No sociodemographic differences were seen between AD and VD. Costs associated with health care resource and primary caregiver utilization were high, being higher in VD than in AD.
Subject(s)
Alzheimer Disease/economics , Alzheimer Disease/epidemiology , Dementia, Vascular/economics , Dementia, Vascular/epidemiology , Health Services for the Aged/statistics & numerical data , Age Distribution , Aged , Aged, 80 and over , Alzheimer Disease/therapy , Cross-Sectional Studies , Dementia, Vascular/therapy , Female , Health Care Costs/statistics & numerical data , Health Expenditures , Health Services for the Aged/economics , Humans , Male , Prevalence , Retrospective Studies , Spain/epidemiologyABSTRACT
No disponible
Subject(s)
Adult , Male , Humans , Tomography, X-Ray Computed , Neurocysticercosis , Seizures , Magnetic Resonance ImagingSubject(s)
Bacteremia/microbiology , Vibrio Infections/diagnosis , Vibrio cholerae , Aged , Humans , MaleSubject(s)
Amyloidosis/diagnosis , Pleural Effusion/diagnosis , Aged , Fatal Outcome , Female , Humans , RecurrenceSubject(s)
Actinomycetales Infections/diagnosis , HIV Infections/complications , HIV-1 , Pneumonia, Bacterial/diagnosis , Actinomycetales Infections/complications , Adult , HIV Infections/microbiology , HIV Infections/pathology , Humans , Lung/pathology , Male , Pneumonia, Bacterial/complications , Rhodococcus equiABSTRACT
The purpose of this study is to contrast a sampling of 20 patients diagnosed as suffering from "Idiopathic Parkinson's Disease" (mean age, 54; schooling, 8.5 years; length of disease, 6.07 years) with a healthy control group, in order to detect possible correlation between intellectual impairment and depression in the individuals affected by Parkinsonism. An integrated battery of neuropsychological testing (PIEN-Test Barcelona. Peña, 1990) was used, in conjunction with "Beck's Depression Inventory". The results show significant differences in the following areas: expressive language, complex language comprehension, motor coordination, complex visuospatial factors, verbal memory and WAIS-type intelligence factors. Discriminant analysis was performed to select the most discriminating variables. The results were as follows, beginning with the most discriminating factor: motor coordination, complex comprehension, complex visuospatial factors, math skills and an overall slowing down. The patients with the highest depression levels were found to have the greatest impairment in mental control/attention and complex comprehension.
Subject(s)
Cognition Disorders/etiology , Parkinson Disease/psychology , Aged , Dementia/epidemiology , Dementia/etiology , Depression/etiology , Depression/psychology , Female , Humans , Male , Middle Aged , Neuropsychological Tests , Parkinson Disease/complications , PrevalenceABSTRACT
The neuropsychological battery PIENC-BARCELONA-86, in experimental phase, is being presented. The study is being done with 37 patients with Alzheimer's disease and 37 control subjects. The selection of the battery's subtests that differ more significantly the pathologies from the control subjects, give us a neuropsychological outline typical in dementia patients and specially in the Alzheimer's disease. The sensitivity and specificity of this battery is of a 67.6% and 92.6%, respectively, that improves up to 100%, when you differ inside the pathological group two subgroups: mild and moderate.
Subject(s)
Alzheimer Disease/diagnosis , Dementia/diagnosis , Neuropsychological Tests , Aged , Aged, 80 and over , Alzheimer Disease/epidemiology , Dementia/epidemiology , Discriminant Analysis , Female , Humans , Male , Middle Aged , Predictive Value of TestsABSTRACT
The evaluation of language in 27 patients with Alzheimer's disease (AD) and 34 normal control individuals disclosed abnormalities in all the patients. An aphasic profile was found, although it was difficult to adscribe to any definite form of aphasia, as, while abnormalities were characteristic of transcorticalism, they also were of anomic type; this suggests a specific AD profile. This type of language abnormality did not correlate with patient's age or sex, the months of evolution of the disease, the years of schooling, or the age at the onset of the disease. There was, however, a close correlation with the degree of dementia.
