ABSTRACT
This is a case report article describing a patient receiving treatment for alopecia with Diane-35, in whom a recruited dominant follicle and a cumulus oophorus were detected by ultrasound. The current perspectives in the detection and control of fertility are discussed and subjected to critical analysis, with emphasis on some results concerning artificial birth control. The recognition of the ovulatory period through physiological changes, the detection of estrogeno-3-glucuronide (E3G) and the luteinizing hormone (LH) is discussed. These methods increase the possibility of understanding the detection of the fertile phase in women, are simple to use, are not invasive, do not have secondary effects, and are not abortive.
Subject(s)
Androgen Antagonists/pharmacology , Contraception , Cyproterone Acetate/pharmacology , Ethinyl Estradiol/pharmacology , Ovulation/drug effects , Adult , Alopecia/drug therapy , Drug Combinations , Female , HumansABSTRACT
A propósito de un caso: Se trata de una paciente en tratamiento poralopecia con Diane-35, en la cual se detecta un folículo dominantereclutado y un cumulus oophorus diagnosticado mediante ecografía. Secomentan las perspectivas actuales en la detección y control de la fertilidadmediante análisis crítico, resaltando algunos resultados relacionadoscon el control artificial de la fertilidad, el reconocimiento del periodoovulatorio mediante la detección de cambios fisiológicos en los órganosdiana del aparato genital femenino, la detección de metabolitosestrógeno-3-glucuronido (E3G) y la hormona luteinizante (LH). Estosúltimos métodos aumentan la disponibilidad de comprender la detecciónde la fase fértil en la mujer, son sencillos de usar, no invasivos,carecen de efectos secundarios y no son abortivos
This is a case report article describing a patient receiving treatment foralopecia with Diane-35, in whom a recruited dominant follicle and acumulus oophorus were detected by ultrasound. The current perspectivesin the detection and control of fertility are discussed and subjected tocritical analysis, with emphasis on some results concerning artificialbirth control. The recognition of the ovulatory period through physiologicalchanges, the detection of estrogeno-3-glucuronide (E3G) and theluteinizing hormone (LH) is discussed. These methods increase thepossibility of understanding the detection of the fertile phase in women,are simple to use, are not invasive, do not have secondary effects, andare not abortive
Subject(s)
Female , Adult , Humans , Androgen Antagonists/pharmacology , Contraception , Cyproterone Acetate/pharmacology , Ethinyl Estradiol/pharmacology , Ovulation , Alopecia/drug therapy , Drug CombinationsABSTRACT
An epidemiologic study has been performed on the relation between the mortality rates from multiple sclerosis for the period 1983-1989 obtained for 36 countries, dietary fat, and latitude. By stepwise multiple regression analysis, saturated fatty acids, animal fat, animal minus fish fat, and latitude correlated independently and positively with multiple sclerosis mortality (p < 0.01-0.001 for fat consumption, and p < 0.05-0.01 for latitude). The ratio of polyunsaturated fatty acids to saturated fatty acids (P/S ratio) and the ratio of unsaturated fatty acids (monounsaturated and polyunsaturated fatty acids) to saturated fatty acids (U/S ratio) correlated independently and negatively with multiple sclerosis mortality (p < 0.05-0.001). These findings support the hypothesis linking dietary fat intake and latitude to multiple sclerosis mortality.
Subject(s)
Dietary Fats/adverse effects , Geography , Multiple Sclerosis/mortality , Developed Countries , Fatty Acids/adverse effects , Female , Humans , Linear Models , Male , Multiple Sclerosis/etiology , Nutrition Surveys , Population Surveillance , Prevalence , Sex DistributionABSTRACT
The effects of two different sources of protein: peas (Pisum sativum var. Belinda) and casein on immunocompetence, nutritional utilization and growth performance have been investigated in recently weaned mice. Feeding these animals on a pea diet resulted in an impairment in growth and significant decreases in the weights of liver, muscle, kidneys and femur, while intestine weights increased. No differences in food consumption were observed, but food conversion efficiency (food intake: weight gain) was increased in pea-fed animals compared with those offered the casein diet. Packed cell volume and serum Fe and Zn levels fell significantly after legume-protein intake, and, by contrast, Cu values increased slightly. Serum albumin levels showed a statistically significant reduction in mice fed on the diet containing peas. However, gamma-globulins and immunoglobulin G titres were markedly increased. The characterization of spleen-cell subsets using monoclonal antibodies revealed a significantly higher percentage of T-lymphocytes in the pea group compared with casein-fed animals, while no changes were observed in the proportions of B-lymphocytes and macrophages. In vitro mitogenic responses to phytohaemagglutinin, concanavalin A and Escherichia coli lipopolysaccharide S were slightly, but not significantly, lower in the pea-fed animals. Our results describe, apparently for the first time in mice, some immunological disturbances after peak intake. These results may lead to a better understanding of the possible role of antigenic proteins in gastrointestinal disorders and the poor individual performance after legume intake.
