ABSTRACT
PURPOSE: To evaluate the effect of the hyperhomocysteinemia on pregnancy rate, implantation rate and abortion rate after IVF. METHOD: Data from a total of 48 infertile couples with hyperhomocysteinemia were prospectively collected for this study. All patients underwent a standard down regulation protocol for ovarian stimulation. Oocytes recovery was performed at 36 h after hCG administration. Embryo transfer took place at 48 h after insemination. The patients were matched in two groups that received or did not receive therapy (group A and B respectively) to normalize homocysteine plasma level. RESULTS: Pregnancy rate, implantation rate and abortion rate varied significantly (pSubject(s)
Abortion, Spontaneous/etiology
, Embryo Implantation
, Fertilization in Vitro
, Hyperhomocysteinemia/complications
, Pregnancy Rate
, Adult
, Female
, Humans
, Pregnancy
, Pregnancy Outcome