ABSTRACT
PURPOSE: Periodic limb movements (PLMs) can be found isolated or related to other sleep disorders, as Obstructive Sleep Apnea (OSA). Nevertheless, this association was described before the proposal for modification of the World Association of Sleep Medicine (WASM), which incorporated major changes modifying the definition of respiratory-related leg movements (RRLM) so that the relationship between OSA and PLM could be affected. METHODS: A total of 131 PSG were studied (children with ages from 5 to 12 years old), all referred because of a suspicion of sleep-disordered breathing (65 children were diagnosed of OSA, and 66 presented snoring but no sleep apnea). Leg movements were manually scored according to both 2006 and 2016 WASM/IRLSSG criteria. RESULTS: According to 2006 WASM rules, statistical differences were found, not only for PLM index (p 0.002), but all indexes. Nevertheless, according to new 2016 WASM rules, no statistical differences were found for PLM index (p 0.677), non-REM PLM index (p 0.299), REM PLM index (P 0.511) or PLM with arousal index (p 0.180), between OSA and non-OSA group. Positive correlation between PLM and RRLM have been found with both set of rules. The percentage of children with PLM>5/h is higher when using the prior PLM scoring criteria developed in 2006 (38.93%) versus the updated PLM scoring criteria (19.08%). CONCLUSION: The lack of association when using the new WASM/IRLSSG scoring rules together with the absence of a previous clear etiopathology explanation may suggest that the association between OSA and PLM might be indeed overestimated and that, perhaps, it really did not exist.
Subject(s)
Sleep Apnea Syndromes , Sleep Apnea, Obstructive , Child , Humans , Child, Preschool , Polysomnography , Movement , LegABSTRACT
INTRODUCTION: Lung transplantation is the final treatment option in patients with respiratory failure. Morbidity and mortality rates associated with the management of complications is high despite advances. Postoperative complications include acute transplant rejection, bronchiolitis obliterans, and infections. Because of that, the success of this treatment option depends on the correct choice of donor and candidates to receive a transplant. OBJECTIVE: This study aims to perform a survival analysis of transplanted patients in our center and determine predictive variables of mortality. PATIENTS AND METHODS: This study is a retrospective assessment of data collected from 510 patients at the Hospital University Reina Sofía from October 1993 to December 31, 2016. Patients who were retransplanted were excluded. We collected data regarding basal characteristics of the donors and candidates to receive a transplant. We analyzed the impact in terms of future survival of basal variables from donor and donor recipients. RESULTS: Five hundred ten patients were included (average age 44 ± 17 years, 69% male), with a maximum follow-up period of 21.6 years (average follow-up 4.52 years, interquartile ratio: 0.13 to 6.97 years). Two hundred twenty-seven patients died (54.3% of the total amount). The influence of donor's basal characteristics on mortality was analyzed; moreover, the relationship between basal variables and survival were analyzed using univariate analysis. Available variables were analyzed through multivariate analysis. CONCLUSION: Lung transplantation is a treatment option with an acceptable risk of morbidity and mortality. Increased awareness of features of evolution could help to reduce postoperative complications.
Subject(s)
Lung Transplantation/mortality , Postoperative Complications/epidemiology , Adolescent , Adult , Female , Graft Rejection/epidemiology , Humans , Kaplan-Meier Estimate , Lung Transplantation/adverse effects , Male , Middle Aged , Multivariate Analysis , Prognosis , Retrospective Studies , Survival AnalysisABSTRACT
INTRODUCCIÓN: Como fase inicial de un proyecto para elaborar una guía clínica sobre neumonía adquirida en la comunidad, se plantea conocer la situación de partida en nuestro centro. OBJETIVO: Evaluar el abordaje diagnóstico y terapéutico en pacientes hospitalizados por neumonía, analizando en los informes clínicos de alta parámetros de calidad previamente publicados. PACIENTES Y MÉTODOS: Estudio observacional, retrospectivo de pacientes ingresados por neumonía en el Hospital Universitario Reina Sofía, de Córdoba, en los últimos 5 años (2010 - 2014). La fuente de información han sido los informes de alta hospitalaria y su correspondiente episodio de urgencias. Se estudiaron variables generales, clínicas e indicadores de calidad, medidos mediante proporciones. RESULTADOS: El total de pacientes ingresados por neumonía fue de 884, seleccionándose aleatoriamente 196 de ellos, 131 hombres (66,8 %) y 65 mujeres (33,2 %), con una edad media de 58 años y una estancia media de 11,56 días. Cumplimiento de los indicadores de calidad: Cualquier tipo de cultivo 70,4%; hemocultivos antes del tratamiento antibiótico 32,7%; determinación antígeno de Legionella y S. Pneumoniae 60,2%; cultivo de esputo 40,8%; broncoaspirado 8,7%; realización de radiografía de tórax al 99%; realización de gasometría arterial 82,1%; tratamiento empírico de acuerdo a las guías 94,9%; pruebas complementarias (hemograma y bioquímica) 99,5%; índices de gravedad PSI/CURB65 0%. CONCLUSIONES: Se reflejan de manera adecuada en un alto porcentaje de pacientes los criterios de calidad indicados en las guías, aunque un claro punto a mejorar es hacer referencia a los índices de gravedad (PSI y CURB65) como criterios de hospitalización
INTRODUCTION: As a project initial stage to draw up a practical guide about Community-Adquired Pneumonia, to know the initial situation in our centre it is approached. OBJECTIVE: To evaluate the diagnostic and therapeutic approach between hospital patients due to pneumonia by analysing quality indicators previously published. METHODS AND MATERIALS: Retrospective observational study of hospitalized patients with pneumonia in University Hospital Reina Sofía, located in Córdoba in the last 5 years (2010- 2014). The source of information was the medical history. General and clinical variable were studied just like quality parameters both measures in proportion. RESULTS: The total amount of hospitalized patients due to pneumonia was 884, chosen at random 196, 131 men (66,8%) and 65 women (33,2%) an average age of 58 and an hospitalized period of 11,56 days. Fulfilment of the quality parameters: any kind of culture 70,4%; blood culture before antibiotic treatment 32,7%; determining Legionella antigen and S. Pneumoniae antigem 60,2%; sputum culture 40,8%; bronchial suction 8,7%; chest X-Ray 99%; arterial blood gas analysis 82,1%; empirical treatment according to regulations 94,9%; additional evidences (blood count and biochemistry) 99,5%; severity rates PSI/CURB65 0%. CONCLUSIONS: It is showed a high rate of patient's percentage quality parameters reordered in regulations, however it is necessary to improve severity rates (PSI and CURB65) such as medical criteria for hospitalization
