Dark Antibacterial Activity of Rose Bengal.

The global spread of bacterial resistance to antibiotics promotes a search for alternative approaches to eradication of pathogenic bacteria. One alternative is using photosensitizers for inhibition of Gram-positive and Gram-negative bacteria under illumination. Due to low penetration of visible light into tissues, applications of photosensitizers are currently limited to treatment of superficial local infections. Excitation of photosensitizers in the dark can be applied to overcome this problem. In the present work, dark antibacterial activity of the photosensitizer Rose Bengal alone and in combination with antibiotics was studied. The minimum inhibitory concentrations (MIC) value of Rose Bengal against S. aureus dropped in the presence of sub-MIC concentrations of ciprofloxacin, levofloxacin, methicillin, and gentamicin. Free Rose Bengal at sub-MIC concentrations can be excited in the dark by ultrasound at 38 kHz. Rose Bengal immobilized onto silicon showed good antibacterial activity in the dark under ultrasonic activation, probably because of Rose Bengal leaching from the polymer during the treatment. Exposure of bacteria to Rose Bengal in the dark under irradiation by electromagnetic radio frequency waves in the 9 to 12 GHz range caused a decrease in the bacterial concentration, presumably due to resonant absorption of electromagnetic energy, its transformation into heat and subsequent excitation of Rose Bengal.

Millimeter Wave High Resolution Radar Accuracy in Fog Conditions-Theory and Experimental Verification.

Attenuation and group delay effects on millimeter wave (MMW) propagation in clouds and fog are studied theoretically and verified experimentally using high resolution radar in an indoor space filled with artificial fog. In the theoretical analysis, the frequency-dependent attenuation and group delay were derived via the permittivity of the medium. The results are applied to modify the millimeter-wave propagation model (MPM) and employed to study the effect of fog and cloud on the accuracy of the Frequency-Modulated Continuous-Wave (FMCW) radar operating in millimeter wavelengths. Artificial fog was generated in the experimental study to demonstrate ultra-low visibility in a confined space. The resulted attenuation and group delay were measured using FMCW radar operating at 320⁻330 GHz. It was found that apart from the attenuation, the incremental group delay caused by the fog also played a role in the accuracy of the radar. The results were compared to the analytical model. It was shown that although the artificial fog has slight different characteristics compare to the natural fog and clouds, in particle composition, size, and density, the model predictions were good, pointing out that the dispersive effects should be considered in the design of remote sensing radars operating in millimeter and sub-millimeter wavelengths.

Multi Ray Model for Near-Ground Millimeter Wave Radar.

A quasi-optical multi-ray model for a short-range millimeter wave radar is presented. The model considers multi-path effects emerging while multiple rays are scattered from the target and reflected to the radar receiver. Among the examined scenarios, the special case of grazing ground reflections is analyzed. Such a case becomes relevant when short range anti-collision radars are employed in vehicles. Such radars operate at millimeter wavelengths, and are aimed at the detection of targets located several tens of meters from the transmitter. Reflections from the road are expected to play a role in the received signal strength, together with the direct line-of-sight beams illuminated and scattered from the target. The model is demonstrated experimentally using radar operating in the W-band. Controlled measurements were done to distinguish between several scattering target features. The experimental setup was designed to imitate vehicle near-ground millimeter wave radars operating in vehicles. A comparison between analytical calculations and experimental results is made and discussed.